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Genetics

D-Index
103
Citations
46844
World Ranking
673
National Ranking
341

Research.com Recognitions

  • 2019 - Fellow of the American Academy of Arts and Sciences
  • 2014 - Member of the National Academy of Sciences
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert B. Darnell is affiliated with Rockefeller University in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with additional work in Medicine. Key subfields for their studies include Molecular Biology, Cancer Research, Rheumatology, Infectious Diseases, and Genetics.

The research topics Robert B. Darnell focuses on include:

  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • MicroRNA in disease regulation
  • RNA regulation and disease
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Rheumatoid Arthritis Research and Therapies

Frequent co-authors collaborating with Robert B. Darnell are:

  • Caryn Hale
  • John J. Fak
  • Mayu O. Frank
  • Dana E. Orange
  • Nathalie E. Blachère

Publication venues where Robert B. Darnell has frequently published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • New England Journal of Medicine
  • Science Translational Medicine
  • Nature Communications

Recent papers authored or co-authored by Robert B. Darnell feature the following titles, years, and publication venues:

  • "Vaccine Breakthrough Infections with SARS-CoV-2 Variants," 2021, New England Journal of Medicine
  • "Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs," 2020, Cell
  • "RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares," 2020, New England Journal of Medicine
  • "Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk," 2021, Nature Genetics
  • "Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis," 2023, Science Translational Medicine

Among awards received by Robert B. Darnell are:

  • Fellow of the American Academy of Arts and Sciences, 2019
  • Member of the National Academy of Sciences, 2014
  • Fellow of the American Association for the Advancement of Science (AAAS), 2010

Best Publications

  • FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

    Jennifer C. Darnell;Sarah J. Van Driesche;Chaolin Zhang;Ka Ying Sharon Hung

  • Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

    Sung Wook Chi;Julie B. Zang;Aldo Mele;Robert B. Darnell

  • De Novo Gene Disruptions in Children on the Autistic Spectrum

    Ivan Iossifov;Michael Ronemus;Dan Levy;Zihua Wang

  • HITS-CLIP yields genome-wide insights into brain alternative RNA processing

    Donny D. Licatalosi;Aldo Mele;John J. Fak;Jernej Ule

  • Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome

    Victoria Brown;Victoria Brown;Peng Jin;Peng Jin;Stephanie Ceman;Stephanie Ceman;Jennifer C. Darnell

  • CLIP identifies Nova-regulated RNA networks in the brain.

    Jernej Ule;Kirk B. Jensen;Kirk B. Jensen;Matteo Ruggiu;Matteo Ruggiu;Aldo Mele;Aldo Mele

  • A call for transparent reporting to optimize the predictive value of preclinical research

    Story C. Landis;Susan G. Amara;Khusru Asadullah;Chris P. Austin

  • Paraneoplastic Syndromes Involving the Nervous System

    Robert B Darnell;Jerome B Posner

  • Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function

    Jennifer C. Darnell;Kirk B. Jensen;Peng Jin;Victoria Brown

  • Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues

    Hong Fei;Hirotaka J. Okano;Cai Li;Gwo-Hwa Lee

  • RNA processing and its regulation: global insights into biological networks

    Donny D. Licatalosi;Robert B. Darnell

  • A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation

    Shengdong Ke;Endalkachew A. Alemu;Claudia Mertens;Emily Conn Gantman

  • Vaccine Breakthrough Infections with SARS-CoV-2 Variants.

    Ezgi Hacisuleyman;Caryn Hale;Yuhki Saito;Nathalie E. Blachere

  • CLIP: a method for identifying protein-RNA interaction sites in living cells.

    Jernej Ule;Kirk Jensen;Aldo Mele;Robert B. Darnell

  • An RNA map predicting Nova-dependent splicing regulation

    Jernej Ule;Giovanni Stefani;Giovanni Stefani;Aldo Mele;Matteo Ruggiu

  • Nova regulates brain-specific splicing to shape the synapse

    Jernej Ule;Aljaž Ule;Joanna Spencer;Alan Williams

  • Dendritic cell maturation is required for the cross-tolerization of CD8+ T cells

    Matthew L. Albert;Mithila Jegathesan;Robert B. Darnell

  • Tumor-specific killer cells in paraneoplastic cerebellar degeneration

    Matthew L. Albert;Jennifer C. Darnell;Armin Bender;Loise M. Francisco

  • Assembly and diploid architecture of an individual human genome via single-molecule technologies

    Matthew Pendleton;Robert Sebra;Andy Wing Chun Pang;Ajay Ummat

  • Nova-1 Regulates Neuron-Specific Alternative Splicing and Is Essential for Neuronal Viability

    Kirk B Jensen;B.Kate Dredge;Giovanni Stefani;Ru Zhong

Frequent Co-Authors

Hirotaka James Okano
Hirotaka James Okano Jikei University School of Medicine
Jernej Ule
Jernej Ule The Francis Crick Institute
Kiran Musunuru
Kiran Musunuru University of Pennsylvania
Jerome B. Posner
Jerome B. Posner Memorial Sloan Kettering Cancer Center
Michael C. Zody
Michael C. Zody New York Genome Center
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Stephen K. Burley
Stephen K. Burley Rutgers, The State University of New Jersey
Olga G. Troyanskaya
Olga G. Troyanskaya Princeton University
Charles M. Rice
Charles M. Rice Rockefeller University

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