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Benjamin J. Blencowe

Benjamin J. Blencowe

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Molecular Biology
Canada
2025

D-Index & Metrics

Genetics

D-Index
95
Citations
44756
World Ranking
886
National Ranking
24

Molecular Biology

D-Index
95
Citations
44756
World Ranking
625
National Ranking
16

Research.com Recognitions

  • 2025 - Research.com Molecular Biology in Canada Leader Award
  • 2019 - Fellow of the Royal Society, United Kingdom
  • 2017 - Fellow of the Royal Society of Canada Academy of Science

Overview

Benjamin J. Blencowe is affiliated with the University of Toronto in Canada and focuses on research primarily within Biochemistry, Genetics, and Molecular Biology. Their work spans multiple subfields, prominently Molecular Biology, Infectious Diseases, Cancer Research, Immunology, and Genetics.

The scientist's research covers various interconnected topics including RNA Research and Splicing, RNA modifications and cancer, RNA and protein synthesis mechanisms, Genomics and Chromatin Dynamics, CRISPR and Genetic Engineering, SARS-CoV-2 and COVID-19 Research, and RNA regulation and disease.

Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Nature Communications
  • Cell Reports
  • Nature Biotechnology

Recent published papers are as follows:

  • Global detection of human variants and isoforms by deep proteome sequencing, 2023, Nature Biotechnology
  • Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform, 2020, Nature Biotechnology
  • Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2, 2020, Molecular Cell
  • Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions, 2020, Molecular Cell
  • SARS-CoV-2 nucleocapsid protein binds host mRNAs and attenuates stress granules to impair host stress response, 2021, iScience

Among frequent co-authors, the most noted are:

  • Ulrich Braunschweig
  • Shaghayegh Farhangmehr
  • Shuye Pu
  • Jack Greenblatt
  • Syed Nabeel-Shah

Benjamin J. Blencowe has received awards including Fellowship of the Royal Society of Canada in 2017, associated with the Academy of Science, and Fellowship of the Royal Society, United Kingdom, in 2019.

Best Publications

  • Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

    Qun Pan;Ofer Shai;Leo J Lee;Brendan J Frey

  • The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation.

    Vidisha Tripathi;Jonathan D. Ellis;Zhen Shen;David Y. Song

  • Transcriptomic analysis of autistic brain reveals convergent molecular pathology

    Irina Voineagu;Xinchen Wang;Patrick G Johnston;Jennifer K Lowe

  • A compendium of RNA-binding motifs for decoding gene regulation

    Debashish Ray;Hilal Kazan;Kate B. Cook;Matthew T. Weirauch;Matthew T. Weirauch

  • The human splicing code reveals new insights into the genetic determinants of disease

    Hui Y. Xiong;Babak Alipanahi;Babak Alipanahi;Leo J. Lee;Leo J. Lee;Hannes Bretschneider

  • Alternative Splicing: New Insights from Global Analyses

    Benjamin J. Blencowe

  • Regulation of Alternative Splicing by Histone Modifications

    Reini F. Luco;Qun Pan;Kaoru Tominaga;Benjamin J. Blencowe

  • The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

    Nuno L. Barbosa-Morais;Nuno L. Barbosa-Morais;Manuel Irimia;Qun Pan;Hui Y. Xiong

  • Deciphering the splicing code

    Yoseph Barash;John A. Calarco;Weijun Gao;Qun Pan

  • Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

    Benjamin J Blencowe

  • Widespread intron retention in mammals functionally tunes transcriptomes

    Ulrich Braunschweig;Nuno L. Barbosa-Morais;Nuno L. Barbosa-Morais;Qun Pan;Emil N. Nachman

  • Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism

    Neelroop N. Parikshak;Vivek Swarup;T. Grant Belgard;Manuel Irimia

  • An RNA map predicting Nova-dependent splicing regulation

    Jernej Ule;Giovanni Stefani;Giovanni Stefani;Aldo Mele;Matteo Ruggiu

  • A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

    Manuel Irimia;Manuel Irimia;Robert J. Weatheritt;Jonathan D. Ellis;Neelroop N. Parikshak

  • Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution

    Jernej Ule;Jernej Ule;Benjamin J. Blencowe

  • Most "dark matter" transcripts are associated with known genes.

    Harm van Bakel;Corey Nislow;Benjamin J. Blencowe;Timothy R. Hughes

  • Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins.

    Debashish Ray;Hilal Kazan;Esther T Chan;Lourdes Peña Castillo

  • Probing microRNAs with microarrays: Tissue specificity and functional inference

    Tomas Babak;Wen Zhang;Quaid Morris;Benjamin J. Blencowe

  • Using expression profiling data to identify human microRNA targets.

    Jim C Huang;Tomas Babak;Timothy W Corson;Timothy W Corson;Timothy W Corson;Gordon Chua

  • Dynamic integration of splicing within gene regulatory pathways.

    Ulrich Braunschweig;Serge Gueroussov;Alex M. Plocik;Brenton R. Graveley

Frequent Co-Authors

Manuel Irimia
Manuel Irimia Pompeu Fabra University
Brendan J. Frey
Brendan J. Frey University of Toronto
Quaid Morris
Quaid Morris Memorial Sloan Kettering Cancer Center
Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Nuno L. Barbosa-Morais
Nuno L. Barbosa-Morais University of Lisbon
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Christos A. Ouzounis
Christos A. Ouzounis Aristotle University of Thessaloniki
Angus I. Lamond
Angus I. Lamond University of Dundee
Jason Moffat
Jason Moffat University of Toronto

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