2023 - Research.com Molecular Biology in United States Leader Award
2022 - Research.com Best Scientist Award
2004 - US President's National Medal of Science "For his contributions to understanding the biochemical pathway of RNA interference phenomena and for his use of RNA interference techniques to perform genetic analyses in mammalian cells.", Presented by President George W. Bush in a White House East Room ceremony on February 13, 2006.
2002 - Fellow of the Royal Society of Edinburgh
1993 - Nobel Prize for their discoveries of split genes
1991 - Member of the National Academy of Medicine (NAM)
1988 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
1988 - Louisa Gross Horwitz Prize, Columbia University
1987 - Fellow of the American Association for the Advancement of Science (AAAS)
1986 - Canada Gairdner International Award
1986 - Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation
1983 - Fellow of the American Academy of Arts and Sciences
1983 - Member of the National Academy of Sciences
His main research concerns Molecular biology, Genetics, RNA, Gene and Cell biology. His studies deal with areas such as DNA, Endonuclease, RNA polymerase II and Transcription factor as well as Molecular biology. Phillip A. Sharp works mostly in the field of Genetics, limiting it down to topics relating to Computational biology and, in certain cases, Biological evolution.
His RNA research is multidisciplinary, relying on both Messenger RNA and splice. His Cell biology research incorporates elements of Cell, Cellular differentiation, Transfection, Argonaute and Protein biosynthesis. His RNA splicing research is multidisciplinary, incorporating elements of Intron and Small nuclear RNA.
His primary areas of investigation include Molecular biology, Cell biology, Gene, Genetics and RNA. His study in Molecular biology is interdisciplinary in nature, drawing from both DNA, Messenger RNA, RNA splicing, RNA polymerase II and Transcription. His Transcription research is multidisciplinary, incorporating perspectives in Promoter and Transcription factor.
His Cell biology study integrates concerns from other disciplines, such as microRNA, Argonaute and Binding site. Genetics is frequently linked to Computational biology in his study. His RNA study improves the overall literature in Biochemistry.
The scientist’s investigation covers issues in Genetics, Cell biology, Computational biology, Gene and microRNA. His Cell biology study combines topics in areas such as Messenger RNA, Alternative splicing, Enhancer, Transcription and Regulation of gene expression. His Computational biology research includes elements of Super-enhancer, Transcriptome, RNA-binding protein and RNA interference.
In his research, Metastasis and Cancer is intimately related to Cancer research, which falls under the overarching field of Gene. The various areas that Phillip A. Sharp examines in his microRNA study include Gene expression, Gene regulatory network, Argonaute, Gene silencing and Dicer. His study ties his expertise on Molecular biology together with the subject of RNA.
Phillip A. Sharp mainly investigates Genetics, Gene, Computational biology, Transcription and microRNA. His research in Gene intersects with topics in Molecular biology and Cancer research. His Molecular biology study incorporates themes from Cell culture, RNase P, Cell growth and Point mutation.
His Transcription research incorporates themes from Transcription factor, RNA polymerase II and Mediator, Cell biology. He has researched Cell biology in several fields, including RNA Splicing Factors, RNA splicing, Alternative splicing and Exon. His research integrates issues of Gene expression, Gene regulatory network, Gene expression profiling, Regulation of gene expression and Dicer in his study of microRNA.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
RNAi: Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals
Phillip D. Zamore;Thomas Tuschl;Phillip A. Sharp;David P. Bartel.
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids
Arnold J. Berk;Phillip A. Sharp.
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Menno P. Creyghton;Albert W. Cheng;G. Grant Welstead;Tristan G. Kooistra.
Proceedings of the National Academy of Sciences of the United States of America (2010)
In vivo genome editing using Staphylococcus aureus Cas9
F. Ann Ran;Le Cong;Winston X. Yan;David A. Scott.
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
Margaret S Ebert;Joel R Neilson;Phillip A Sharp.
Nature Methods (2007)
Gene silencing in mammals by small interfering RNAs
Michael T. McManus;Phillip A. Sharp.
Nature Reviews Genetics (2002)
Specificity of microRNA target selection in translational repression
John G. Doench;Phillip A. Sharp.
Genes & Development (2004)
Roles for MicroRNAs in Conferring Robustness to Biological Processes
Margaret S. Ebert;Phillip A. Sharp.
Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters
Andrea Ventura;Amanda G. Young;Monte M. Winslow;Laura Lintault.
Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis
Phillip A. Sharp;Bill Sugden;Joe Sambrook.
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: