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2025
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Molecular Biology
USA
2026

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Best Scientists

D-Index
188
Citations
126193
World Ranking
457
National Ranking
300

Molecular Biology

D-Index
190
Citations
130634
World Ranking
25
National Ranking
17

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2021 - Kyoto Prize in Life sciences Discovery of the Principle of Gene Transcription Mechanisms in Eukaryotes
  • 2012 - Albany Medical Center Prize in Medicine and Biomedical Research
  • 2003 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 2000 - Canada Gairdner International Award
  • 1999 - Louisa Gross Horwitz Prize, Columbia University
  • 1999 - Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation
  • 1995 - Fellow of the American Academy of Arts and Sciences
  • 1992 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1988 - Member of the National Academy of Sciences

Overview

Robert G. Roeder is affiliated with Rockefeller University in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial work related to medicine. Key subfields of study include molecular biology, immunology, hematology, oncology, and cancer research.

The scientist's research covers a range of topics, including:

  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • Protein Degradation and Inhibitors
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Acute Myeloid Leukemia Research
  • Ubiquitin and proteasome pathways

Frequent publication venues where Robert G. Roeder's work appears include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Molecular Cell
  • Nature Communications
  • Cell

Recent significant papers include:

  • "Functional partitioning of transcriptional regulators by patterned charge blocks" (2023, Cell)
  • "A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms" (2020, Cell)
  • "The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway" (2021, Science Advances)
  • "EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis" (2022, Nature Cell Biology)
  • "Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma" (2020, Cancer Discovery)

Robert G. Roeder has collaborated frequently with several researchers, including Chi-Shuen Chu, Keiichi Ito, Wei-Yi Chen, Sohail Malik, and Ari Melnick.

The scientist's professional recognition includes multiple awards:

  • Kyoto Prize in Life Sciences (2021) for the discovery of the principle of gene transcription mechanisms in eukaryotes
  • Albany Medical Center Prize in Medicine and Biomedical Research (2012)
  • Albert Lasker Award for Basic Medical Research (2003)
  • Canada Gairdner International Award (2000)
  • Louisa Gross Horwitz Prize, Columbia University (1999)
  • Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation (1999)
  • Fellow of the American Academy of Arts and Sciences (1995)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1992)
  • Member of the National Academy of Sciences (1988)

Best Publications

  • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

    John David Dignam;Russell M. Lebovitz;Robert G. Roeder

  • Metabolic regulation of gene expression by histone lactylation

    Di Zhang;Zhanyun Tang;He Huang;He Huang;Guolin Zhou

  • Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

    Wei Gu;Robert G Roeder

  • Coactivator condensation at super-enhancers links phase separation and gene control

    Benjamin R. Sabari;Alessandra Dall’Agnese;Ann Boija;Isaac A. Klein;Isaac A. Klein

  • The role of general initiation factors in transcription by RNA polymerase II.

    Robert G. Roeder

  • Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

    Michèle Sawadogo;Robert G. Roeder

  • Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms

    Robert G. Roeder;Robert G. Roeder;William J. Rutter;William J. Rutter

  • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

    Assam El-Osta;Daniella Brasacchio;Dachun Yao;Alessandro Pocai

  • Human PAD4 regulates histone arginine methylation levels via demethylimination.

    Yanming Wang;Joanna Wysocka;Joyce Sayegh;Young-Ho Lee

  • Eukaryotic gene transcription with purified components.

    John D. Dignam;Paul L. Martin;Barkur S. Shastry;Robert G. Roeder

  • Specific Inhibition of Nuclear RNA Polymerase II by α-Amanitin

    Thomas J. Lindell;Fanyela Weinberg;Paul W. Morris;Robert G. Roeder

  • BIOCHEMISTRY AND STRUCTURAL BIOLOGY OF TRANSCRIPTION FACTOR IID (TFIID)

    S. K. Burley;R. G. Roeder

  • WDR5 Associates with Histone H3 Methylated at K4 and Is Essential for H3 K4 Methylation and Vertebrate Development

    Joanna Wysocka;Tomek Swigut;Thomas A. Milne;Yali Dou

  • Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

    David R. Engelke;Sun Yu Ng;B. S. Shastry;Robert G. Roeder

  • Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna

    P. Anthony Weil;Donal S. Luse;Jacqueline Segall;Robert G. Roeder

  • Regulation of MLL1 H3K4 methyltransferase activity by its core components

    Yali Dou;Thomas A Milne;Alexander J Ruthenburg;Alexander J Ruthenburg;Seunghee Lee

  • Chromatin structure analyses identify miRNA promoters

    Fatih Ozsolak;Laura L. Poling;Zhengxin Wang;Hui Liu

  • Synergistic activation of transcription by CBP and p53

    Wei Gu;Xiao-Lu Shi;Robert G. Roeder

  • Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

    Joseph D. Fondell;Hui Ge;Robert G. Roeder

  • Crystal structure of a TFIIB-TBP-TATA-element ternary complex.

    Dimitar B. Nikolov;Hua Chen;Hua Chen;Elaine D. Halay;Elaine D. Halay;Anny A. Usheva

Frequent Co-Authors

Masami Horikoshi
Masami Horikoshi University of Tokyo
C. David Allis
C. David Allis Rockefeller University
Thomas A. Milne
Thomas A. Milne University of Oxford
Brian T. Chait
Brian T. Chait Rockefeller University
Ari Melnick
Ari Melnick Cornell University
Hua Xiao
Hua Xiao Michigan State University
Nathaniel Heintz
Nathaniel Heintz Rockefeller University
Stephen K. Burley
Stephen K. Burley Rutgers, The State University of New Jersey
Tom W. Muir
Tom W. Muir Princeton University
Ananda L. Roy
Ananda L. Roy Technical University of Munich

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