D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Molecular Biology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best Scientists D-index 175 Citations 110,781 553 World Ranking 515 National Ranking 346
Molecular Biology D-index 174 Citations 110,117 541 World Ranking 20 National Ranking 16

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in United States Leader Award

2022 - Research.com Best Scientist Award

2021 - Kyoto Prize in Life sciences Discovery of the Principle of Gene Transcription Mechanisms in Eukaryotes

2012 - Albany Medical Center Prize in Medicine and Biomedical Research

2003 - Albert Lasker Award for Basic Medical Research, Lasker Foundation

2000 - Canada Gairdner International Award

1999 - Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation

1999 - Louisa Gross Horwitz Prize, Columbia University

1995 - Fellow of the American Academy of Arts and Sciences

1992 - Fellow of the American Association for the Advancement of Science (AAAS)

1988 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Transcription factor

His primary areas of investigation include Molecular biology, Cell biology, RNA polymerase II, Genetics and Transcription. His Molecular biology research is multidisciplinary, incorporating elements of RNA, Thyroid hormone receptor, Psychological repression, PCAF and RNA polymerase I. His studies deal with areas such as Coactivator, MED1, Chromatin and P300-CBP Transcription Factors as well as Cell biology.

His RNA polymerase II research includes elements of RNA-dependent RNA polymerase, Transcription factor II D, Transcription factor II H, Eukaryotic transcription and General transcription factor. His work carried out in the field of Transcription factor II D brings together such families of science as Transcription factor II A, Sigma factor and RNA polymerase II holoenzyme. He focuses mostly in the field of Transcription, narrowing it down to matters related to Transcription factor and, in some cases, Promoter, Histone H2B and Histone octamer.

His most cited work include:

  • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei (9623 citations)
  • Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain (2255 citations)
  • The role of general initiation factors in transcription by RNA polymerase II. (945 citations)

What are the main themes of his work throughout his whole career to date?

Molecular biology, Cell biology, Transcription factor, Transcription and RNA polymerase II are his primary areas of study. His Molecular biology study combines topics in areas such as RNA, RNA polymerase III, Promoter, Transcription factor II D and RNA polymerase I. His Cell biology research incorporates themes from MED1, Coactivator, Genetics and Chromatin.

Robert G. Roeder has included themes like Regulation of gene expression and Histone octamer in his Transcription factor study. The Transcription study combines topics in areas such as Gene expression and DNA. His studies deal with areas such as Protein subunit, RNA polymerase, Transcriptional regulation and Eukaryotic transcription as well as RNA polymerase II.

He most often published in these fields:

  • Molecular biology (53.19%)
  • Cell biology (38.80%)
  • Transcription factor (29.51%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (38.80%)
  • Histone (9.47%)
  • Transcription (28.05%)

In recent papers he was focusing on the following fields of study:

Robert G. Roeder mainly focuses on Cell biology, Histone, Transcription, Transcription factor and RNA polymerase II. His work carried out in the field of Cell biology brings together such families of science as Chromatin, Genetics, Regulation of gene expression and Transcriptional regulation. His study looks at the relationship between Transcription and topics such as Fusion protein, which overlap with Plasma protein binding.

His research in Transcription factor intersects with topics in Molecular biology and Ternary complex. His Molecular biology research is multidisciplinary, incorporating perspectives in Haematopoiesis, Response element, DNA and Stromal cell. Robert G. Roeder interconnects Cell, Cyclin-dependent kinase 9, Transcription factor II B, General transcription factor and Transcription factor II D in the investigation of issues within RNA polymerase II.

Between 2012 and 2021, his most popular works were:

  • Coactivator condensation at super-enhancers links phase separation and gene control (699 citations)
  • Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation (266 citations)
  • H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation (260 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Transcription factor

His main research concerns Cell biology, Transcription factor, Genetics, Histone and Regulation of gene expression. The various areas that he examines in his Cell biology study include Chromatin, Gene silencing, Cellular differentiation and Transcription factor II A. His study looks at the relationship between Histone and fields such as Acetylation, as well as how they intersect with chemical problems.

His Regulation of gene expression research is multidisciplinary, incorporating elements of Enhancer, Gene expression, Cancer research and Coactivator. His RNA polymerase II research integrates issues from Transcription factor II E, General transcription factor, Core mediator complex, Mediator and Transcription factor II D. His study brings together the fields of Molecular biology and Histone methyltransferase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam;Russell M. Lebovitz;Robert G. Roeder.
Nucleic Acids Research (1983)

12934 Citations

Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

Wei Gu;Robert G Roeder.
Cell (1997)

3296 Citations

The role of general initiation factors in transcription by RNA polymerase II.

Robert G. Roeder.
Trends in Biochemical Sciences (1996)

1533 Citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

Michèle Sawadogo;Robert G. Roeder.
Cell (1985)

1395 Citations

Coactivator condensation at super-enhancers links phase separation and gene control

Benjamin R. Sabari;Alessandra Dall’Agnese;Ann Boija;Isaac A. Klein;Isaac A. Klein.
Science (2018)

1255 Citations

Multiple Forms of DNA-dependent RNA Polymerase in Eukaryotic Organisms

Robert G. Roeder;Robert G. Roeder;William J. Rutter;William J. Rutter.
Nature (1969)

1194 Citations

Human PAD4 regulates histone arginine methylation levels via demethylimination.

Yanming Wang;Joanna Wysocka;Joyce Sayegh;Young-Ho Lee.
Science (2004)

1113 Citations

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

Assam El-Osta;Daniella Brasacchio;Dachun Yao;Alessandro Pocai.
Journal of Experimental Medicine (2008)

1113 Citations

Eukaryotic gene transcription with purified components.

John D. Dignam;Paul L. Martin;Barkur S. Shastry;Robert G. Roeder.
Methods in Enzymology (1983)

1108 Citations

BIOCHEMISTRY AND STRUCTURAL BIOLOGY OF TRANSCRIPTION FACTOR IID (TFIID)

S. K. Burley;R. G. Roeder.
Annual Review of Biochemistry (1996)

999 Citations

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