What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Internal medicine
His scientific interests lie mostly in Immunology, Germinal center, Antigen, Interleukin 21 and CD40.
Matthew C. Cook studies Immunology, namely Naive B cell.
His Germinal center study combines topics in areas such as Molecular biology, Somatic hypermutation and Autoantibody.
His Antigen research is multidisciplinary, relying on both Interleukin, Immunoglobulin E, Innate immune system and Candida albicans.
His Interleukin 21 research integrates issues from Systemic lupus erythematosus, Adoptive cell transfer, Autoimmunity and BCL6.
His research investigates the connection between CD40 and topics such as B cell selection that intersect with issues in Antigen-presenting cell, Affinity maturation, Follicular dendritic cells and Interleukin 4.
His most cited work include:
- A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity (706 citations)
- Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3 (542 citations)
- Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3 (542 citations)
What are the main themes of his work throughout his whole career to date?
Matthew C. Cook mostly deals with Immunology, Immune system, Antigen, Cell biology and Antibody.
His study in Cellular differentiation extends to Immunology with its themes.
His Immune system research incorporates elements of Mutation, Effector and Vaccination.
In Antigen, Matthew C. Cook works on issues like CD40, which are connected to Bruton's tyrosine kinase.
His study looks at the intersection of Cell biology and topics like IL-2 receptor with Interleukin 10.
His studies in Interleukin 21 integrate themes in fields like Cancer research, BCL6, Interleukin 4 and CXCR5.
He most often published in these fields:
- Immunology (67.01%)
- Immune system (30.41%)
- Antigen (26.29%)
What were the highlights of his more recent work (between 2018-2021)?
- Antigen (26.29%)
- Whole genome sequencing (5.67%)
- Genetics (18.04%)
In recent papers he was focusing on the following fields of study:
Matthew C. Cook mainly investigates Antigen, Whole genome sequencing, Genetics, Immunology and Missense mutation.
His research integrates issues of Virology, Assay sensitivity, T cell, Antibody and Seroprevalence in his study of Antigen.
Matthew C. Cook works mostly in the field of T cell, limiting it down to topics relating to Cell biology and, in certain cases, Mutation, as a part of the same area of interest.
His Whole genome sequencing study integrates concerns from other disciplines, such as Strain, Genetic variation and Sequence.
In his work, Matthew C. Cook performs multidisciplinary research in Immunology and Antigen Sensitization.
His Missense mutation research includes elements of Lupus erythematosus, Short read and Allele frequency.
Between 2018 and 2021, his most popular works were:
- Hypomorphic caspase activation and recruitment domain 11 ( CARD11 ) mutations associated with diverse immunologic phenotypes with or without atopic disease (35 citations)
- Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus (28 citations)
- Regulatory roles of IL-10-producing human follicular T cells. (20 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Internal medicine
His main research concerns Antigen, Immunology, T cell, Immune system and Mutation.
The concepts of his Antigen study are interwoven with issues in Assay sensitivity, Seroepidemiologic Studies, Confidence interval and Virology.
Many of his studies involve connections with topics such as Penetrance and Immunology.
His T cell study incorporates themes from Immunoglobulin E, FOXP3, Interleukin 10 and B cell.
In the field of Immune system, his study on Keyhole limpet hemocyanin, Immunity and Immunization overlaps with subjects such as Antibody titer.
His Mutation research integrates issues from Cell, Cell biology, Mucosal associated invariant T cell and Ligand.
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