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Immunology

D-Index
106
Citations
56400
World Ranking
556
National Ranking
333

Medicine

D-Index
106
Citations
56400
World Ranking
6397
National Ranking
3408

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2012 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

Shane Crotty is affiliated with the La Jolla Institute For Allergy & Immunology in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with notable contributions in Immunology, Infectious Diseases, Molecular Biology, Virology, and Epidemiology.

Their body of work extensively covers topics including SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, T-cell and B-cell Immunology, HIV Research and Treatment, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, as well as vaccines and immunoinformatics approaches.

Key papers authored by Shane Crotty and collaborators include:

  • Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals, 2020, Cell
  • Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection, 2021, Science
  • Adaptive immunity to SARS-CoV-2 and COVID-19, 2021, Cell
  • Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity, 2020, Cell
  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans, 2020, Science

Frequent coauthors of Shane Crotty include:

  • Alessandro Sette
  • Jennifer M. Dan
  • William R. Schief
  • Daniela Weiskopf
  • Alba Grifoni

Their research has been published primarily in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Science Immunology
  • Science
  • SSRN Electronic Journal

Shane Crotty has been recognized with awards including the Fellow of the American Association for the Advancement of Science (AAAS) in 2019 and the AAI-BD Biosciences Investigator Award from the American Association of Immunologists in 2012.

Best Publications

  • Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.

    Alba Grifoni;Daniela Weiskopf;Sydney I. Ramirez;Sydney I. Ramirez;Jose Mateus

  • Follicular Helper CD4 T Cells (TFH)

    Shane Crotty

  • Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection.

    Jennifer M. Dan;Jennifer M. Dan;Jose Mateus;Yu Kato;Kathryn M. Hastie

  • Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation.

    Robert J. Johnston;Amanda C. Poholek;Daniel DiToro;Isharat Yusuf

  • T follicular helper cell differentiation, function, and roles in disease

    Shane Crotty

  • Adaptive immunity to SARS-CoV-2 and COVID-19.

    Alessandro Sette;Alessandro Sette;Shane Crotty;Shane Crotty

  • Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity.

    Carolyn Rydyznski Moderbacher;Sydney I. Ramirez;Sydney I. Ramirez;Jennifer M. Dan;Jennifer M. Dan;Alba Grifoni

  • T Follicular Helper Cell Biology: A Decade of Discovery and Diseases

    Shane Crotty

  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

    Jose Mateus;Alba Grifoni;Alison Tarke;John Sidney

  • ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6.

    Youn Soo Choi;Robin Kageyama;Danelle Eto;Tania C. Escobar

  • RNA virus error catastrophe: direct molecular test by using ribavirin.

    Shane Crotty;Craig E. Cameron;Raul Andino

  • The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen.

    Shane Crotty;David Maag;Jamie J. Arnold;Weidong Zhong

  • Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

    Michela Locci;Michela Locci;Colin Havenar-Daughton;Colin Havenar-Daughton;Elise Landais;Jennifer Wu

  • The Transcription Factor NFAT Promotes Exhaustion of Activated CD8+ T Cells

    Gustavo J. Martinez;Renata M. Pereira;Tarmo Äijö;Tarmo Äijö;Edward Y. Kim

  • Cutting Edge: Long-Term B Cell Memory in Humans after Smallpox Vaccination

    Shane Crotty;Phil Felgner;Huw Davies;John Glidewell

  • Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

    Luis J. Sigal;Shane Crotty;Raul Andino;Kenneth L. Rock

  • Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation

    Shane Crotty;Robert J Johnston;Robert J Johnston;Stephen P Schoenberger

  • Resolution of a chronic viral infection after interleukin-10 receptor blockade

    Mette Ejrnaes;Christophe M. Filippi;Marianne M. Martinic;Eleanor M. Ling

  • Runx3 programs CD8 + T cell residency in non-lymphoid tissues and tumours

    J. Justin Milner;Clara Toma;Bingfei Yu;Kai Zhang

  • IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

    Danelle Eto;Christopher Lao;Daniel DiToro;Burton Barnett

  • A brief history of T cell help to B cells.

    Shane Crotty

  • Impact of SARS-CoV-2 variants on the total CD4 + and CD8 + T cell reactivity in infected or vaccinated individuals.

    Alison Tarke;Alison Tarke;John Sidney;Nils Methot;Esther Dawen Yu

Frequent Co-Authors

Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology
Guido Silvestri
Guido Silvestri Emory University
William R. Schief
William R. Schief Scripps Research Institute
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Rafi Ahmed
Rafi Ahmed Emory University
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Daniel W. Kulp
Daniel W. Kulp The Wistar Institute
Darrell J. Irvine
Darrell J. Irvine Scripps Research Institute

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