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Biology and Biochemistry

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196
Citations
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World Ranking
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Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2016 - Member of the National Academy of Sciences
  • 2008 - Fellow of the Royal Society of Edinburgh
  • 2002 - Fellow of the American Academy of Arts and Sciences
  • 2000 - Fellow of the Royal Society, United Kingdom

Overview

Ian A. Wilson is affiliated with the Scripps Research Institute in the United States. Their research primarily focuses on the field of medicine, encompassing several critical subfields and topics related to infectious diseases and molecular biology.

The scientist's main areas of study include:

  • Medicine
  • Infectious Diseases
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Immunology
  • Epidemiology

Wilson's research topics cover a wide spectrum within virology and immunology, with significant contributions to:

  • SARS-CoV-2 and COVID-19 Research
  • Monoclonal and Polyclonal Antibodies Research
  • HIV Research and Treatment
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Influenza Virus Research Studies
  • COVID-19 Clinical Research Studies

Their recent publications demonstrate involvement in high-impact research regarding viral immunology and structural biology. Some notable recent papers include:

  • A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV, 2020, Science
  • Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model, 2020, Science
  • Structural basis of a shared antibody response to SARS-CoV-2, 2020, Science
  • Design of protein-binding proteins from the target structure alone, 2022, Nature
  • Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections, 2020, Cell Reports

Wilson commonly collaborates with a set of frequent co-authors who contribute to significant research projects. These include:

  • Meng Yuan
  • Andrew B. Ward
  • Nicholas C. Wu
  • Xueyong Zhu
  • Hejun Liu

The main publication venues for Wilson's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Cell Reports
  • Science

Wilson has also contributed to book publications. One listed work is:

  • Praying to the Temple, published by Peeters in 2022

Awards received by Wilson recognize their contributions to scientific communities, including:

  • Member of the National Academy of Sciences, 2016
  • Fellow of the Royal Society of Edinburgh, 2008
  • Fellow of the American Academy of Arts and Sciences, 2002
  • Fellow of the Royal Society, United Kingdom, 2000

Best Publications

  • Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution.

    I. A. Wilson;J. J. Skehel;D. C. Wiley

  • Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

    D. C. Wiley;I. A. Wilson;J. J. Skehel

  • Glycosylation and the immune system

    Pauline M. Rudd;Tim Elliott;Peter Cresswell;Ian A. Wilson

  • An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex

    K. Christopher Garcia;Massimo Degano;Robyn L. Stanfield;Anders Brunmark

  • Broad neutralization coverage of HIV by multiple highly potent antibodies

    Laura M. Walker;Michael Huber;Michael Huber;Katie J. Doores;Katie J. Doores;Emilia Falkowska;Emilia Falkowska

  • New world bats harbor diverse influenza A viruses.

    Suxiang Tong;Xueyong Zhu;Yan Li;Mang Shi

  • How TCRs Bind MHCs, Peptides, and Coreceptors

    Markus G. Rudolph;Robyn L. Stanfield;Ian A. Wilson

  • A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV.

    Meng Yuan;Nicholas C. Wu;Xueyong Zhu;Chang Chun D. Lee

  • Antibody Recognition of a Highly Conserved Influenza Virus Epitope

    Damian C. Ekiert;Gira Bhabha;Marc-André Elsliger;Robert H. E. Friesen

  • Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.

    Thomas F. Rogers;Thomas F. Rogers;Fangzhu Zhao;Deli Huang;Nathan Beutler

  • Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

    Ola Blixt;Steve Head;Tony Mondala;Christopher Scanlan

  • The structure of an antigenic determinant in a protein

    Ian A. Wilson;Henry L. Niman;Richard A. Houghten;Andrew R. Cherenson

  • Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

    J. Field;J. Nikawa;D. Broek;B. MacDonald

  • Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus

    James Stevens;Ola Blixt;Terrence M. Tumpey;Jeffery K. Taubenberger

  • Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.

    Daved H. Fremont;Masazumi Matsumura;Enrico A. Stura;Per A. Peterson

  • Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.

    Erica Ollmann Saphire;Paul W. H. I. Parren;Ralph Pantophlet;Michael B. Zwick

  • HIV vaccine design and the neutralizing antibody problem

    Dennis R Burton;Ronald C Desrosiers;Robert W Doms;Wayne C Koff

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

    Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman

  • Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion.

    J J Skehel;P M Bayley;E B Brown;S R Martin

  • Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition

    Daniel A. Calarese;Christopher N. Scanlan;Michael B. Zwick;Songpon Deechongkit

Frequent Co-Authors

Scott A. Lesley
Scott A. Lesley Genomics Institute of the Novartis Research Foundation
Adam Godzik
Adam Godzik University of California, Riverside
Robyn L. Stanfield
Robyn L. Stanfield Scripps Research Institute
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Lukasz Jaroszewski
Lukasz Jaroszewski Discovery Institute
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Sanjay Krishna
Sanjay Krishna The Ohio State University
Keith O. Hodgson
Keith O. Hodgson Stanford University
Enrico A. Stura
Enrico A. Stura University of Paris-Saclay

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