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Biology and Biochemistry

D-Index
67
Citations
25155
World Ranking
8062
National Ranking
3652

Overview

Robyn L. Stanfield is affiliated with the Scripps Research Institute in the United States and has contributed extensively to the fields of medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their research spans multiple subfields including molecular biology, immunology, infectious diseases, radiology, nuclear medicine and imaging, and virology.

Stanfield's work focuses on several main topics such as monoclonal and polyclonal antibodies research, glycosylation and glycoproteins research, HIV research and treatment, immune cell function and interaction, viral infections and outbreaks research, amyloidosis diagnosis, treatment and outcomes, as well as viral gastroenteritis research and epidemiology.

Frequent publication venues for their research include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Science Advances
  • Journal of the American Chemical Society

Stanfield's recent papers reflect a diverse range of topics in immunology and infectious diseases. These include:

  • "Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines" (2021), published in Nature Communications
  • "Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins" (2024), published in Science Translational Medicine
  • "Structural basis of broad HIV neutralization by a vaccine-induced cow antibody" (2020), published in Science Advances
  • "An alternate conformation of HCV E2 neutralizing face as an additional vaccine target" (2020), published in Science Advances
  • "50 Years of structural immunology" (2021), published in Journal of Biological Chemistry

Collaborating frequently with other researchers, Stanfield has worked alongside:

  • Ian A. Wilson
  • Andrew B. Ward
  • Linling He
  • Dennis R. Burton
  • Devin Sok

Best Publications

  • An αβ T cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex

    K. Christopher Garcia;Massimo Degano;Robyn L. Stanfield;Anders Brunmark

  • How TCRs Bind MHCs, Peptides, and Coreceptors

    Markus G. Rudolph;Robyn L. Stanfield;Ian A. Wilson

  • Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.

    Erica Ollmann Saphire;Paul W. H. I. Parren;Ralph Pantophlet;Michael B. Zwick

  • Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition

    Daniel A. Calarese;Christopher N. Scanlan;Michael B. Zwick;Songpon Deechongkit

  • Structure of a V3-Containing HIV-1 gp120 Core

    Chih-chin Huang;Min Tang;Mei-Yun Zhang;Shahzad Majeed

  • Crystal structure of a soluble cleaved HIV-1 envelope trimer.

    Jean-Philippe Julien;Jean-Philippe Julien;Albert Cupo;Devin Sok;Devin Sok;Robyn L. Stanfield;Robyn L. Stanfield

  • The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120

    Christopher N. Scanlan;Ralph Pantophlet;Mark R. Wormald;Erica Ollmann Saphire

  • A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

    Robert Pejchal;Katie J. Doores;Katie J. Doores;Laura M. Walker;Reza Khayat

  • Antibody-antigen interactions: new structures and new conformational changes

    Ian A. Wilson;Robyn L. Stanfield

  • Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

    Dennis R. Burton;Dennis R. Burton;Pascal Poignard;Robyn L. Stanfield;Ian A. Wilson

  • Broadly Neutralizing Anti-HIV Antibody 4E10 Recognizes a Helical Conformation of a Highly Conserved Fusion-Associated Motif in gp41

    Rosa M.F. Cardoso;Michael B. Zwick;Robyn L. Stanfield;Renate Kunert

  • Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4.

    Chih Chin Huang;Son N. Lam;Priyamvada Acharya;Min Tang

  • Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A

    Robyn L. Stanfield;Terry M. Fieser;Richard A. Lerner;Ian A. Wilson

  • Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

    Leopold Kong;Erick Giang;Travis Nieusma;Rameshwar U. Kadam

  • Antibody vs. HIV in a clash of evolutionary titans

    Dennis R. Burton;Robyn L. Stanfield;Ian A. Wilson

  • HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

    Jon M. Steichen;Daniel W. Kulp;Talar Tokatlian;Amelia Escolano

  • Antibody-antigen interactions

    Ian A. Wilson;Robyn L. Stanfield

  • Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

    Leopold Kong;Jeong Hyun Lee;Katie J Doores;Katie J Doores;Katie J Doores;Charles D Murin

  • Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.

    Jean-Philippe Julien;Devin Sok;Reza Khayat;Jeong Hyun Lee

  • Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12

    Daniel A. Calarese;Hing-Ken Lee;Cheng-Yuan Huang;Michael D. Best

Frequent Co-Authors

Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Andrew B. Ward
Andrew B. Ward Scripps Research Institute
Peter E. Wright
Peter E. Wright Scripps Research Institute
Jean-Philippe Julien
Jean-Philippe Julien University of Toronto
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Devin Sok
Devin Sok Scripps Research Institute
Enrico A. Stura
Enrico A. Stura University of Paris-Saclay
John P. Moore
John P. Moore Cornell University
Michael B. Zwick
Michael B. Zwick Scripps Research Institute

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