D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 94 Citations 33,307 263 World Ranking 367 National Ranking 228

Overview

What is he best known for?

The fields of study he is best known for:

  • Antibody
  • Virus
  • Gene

Virology, Antibody, Immunology, Neutralization and Virus are his primary areas of study. His Virology study combines topics in areas such as Epitope, Gp41 and Lentivirus. His Epitope research is multidisciplinary, relying on both B cell, Immunogen, Recombinant DNA and Binding site.

His Antibody research is multidisciplinary, incorporating elements of Glycoprotein, Glycan and Antigen. He combines subjects such as Immunoglobulin G, Complementarity determining region, Peptide sequence, Potency and Molecular biology with his study of Neutralization. His Virus research includes themes of Innate immune system and Vaccine trial.

His most cited work include:

  • Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 (1410 citations)
  • An immunogenic personal neoantigen vaccine for patients with melanoma (1092 citations)
  • Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. (887 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Virology, Antibody, Immunology, Neutralization and Epitope. The study incorporates disciplines such as Monoclonal antibody, Immune system and Antigen in addition to Virology. His Antibody research integrates issues from Glycoprotein and Glycan.

His research in Neutralization intersects with topics in Recombinant DNA, Potency, Molecular biology, Viral entry and Protein structure. His Epitope research includes themes of Viral envelope, Glycosylation, Binding site and Immunoglobulin G. His study in Virus is interdisciplinary in nature, drawing from both Clade and Lentivirus.

He most often published in these fields:

  • Virology (87.08%)
  • Antibody (65.23%)
  • Immunology (43.69%)

What were the highlights of his more recent work (between 2017-2021)?

  • Antibody (65.23%)
  • Virology (87.08%)
  • Neutralization (33.54%)

In recent papers he was focusing on the following fields of study:

Michael S. Seaman mainly investigates Antibody, Virology, Neutralization, Epitope and Immune system. His research on Antibody concerns the broader Immunology. His work on Viremia, Virus and Viral load is typically connected to Macaque as part of general Virology study, connecting several disciplines of science.

His Neutralization research includes elements of In vitro, Potency and In vivo. His Epitope study combines topics in areas such as Transmembrane protein, Immunoglobulin G and Cell biology. Michael S. Seaman combines subjects such as Mutation and Recombinant DNA with his study of Immune system.

Between 2017 and 2021, his most popular works were:

  • Combination Therapy with anti-HIV-1 Antibodies Maintains Viral Suppression (193 citations)
  • Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host. (168 citations)
  • Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals. (111 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Virus

Michael S. Seaman mainly focuses on Antibody, Virology, Neutralization, Viremia and Virus. The concepts of his Antibody study are interwoven with issues in Immune system, Immunotherapy and Antigen. His Immune system study deals with the bigger picture of Immunology.

His Virology study combines topics from a wide range of disciplines, such as Priming, Immunogen and Fatal outcome. His research integrates issues of In vitro, Potency and In vivo in his study of Neutralization. As a part of the same scientific study, Michael S. Seaman usually deals with the Virus, concentrating on Immunization and frequently concerns with CRISPR.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

Xueling Wu;Zhi Yong Yang;Yuxing Li;Carl Magnus Hogerkorp.
Science (2010)

1612 Citations

An immunogenic personal neoantigen vaccine for patients with melanoma

Patrick A. Ott;Zhuting Hu;Derin B. Keskin;Derin B. Keskin;Sachet A. Shukla;Sachet A. Shukla.
Nature (2017)

1054 Citations

Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.

Johannes F. Scheid;Hugo Mouquet;Beatrix Ueberheide;Ron Diskin.
Science (2011)

1033 Citations

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Johannes F. Scheid;Hugo Mouquet;Niklas Feldhahn;Michael S. Seaman.
Nature (2009)

866 Citations

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

Dan H. Barouch;James B. Whitney;Brian Moldt;Florian Klein.
Nature (2013)

618 Citations

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies.

Michael S. Seaman;Holly Janes;Natalie Hawkins;Lauren E. Grandpre.
Journal of Virology (2010)

612 Citations

Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117

Marina Caskey;Florian Klein;Julio C. C. Lorenzi;Michael S. Seaman.
Nature (2015)

529 Citations

Immune Control of an SIV Challenge by a T Cell-Based Vaccine in Rhesus Monkeys

Jinyan Liu;Kara L. O’Brien;Diana M. Lynch;Nathaniel L. Simmons.
Nature (2009)

510 Citations

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

Florian Klein;Ariel Halper-Stromberg;Joshua A. Horwitz;Henning Gruell;Henning Gruell.
Nature (2012)

497 Citations

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.

Hugo Mouquet;Louise Scharf;Zelda Euler;Yan Liu.
Proceedings of the National Academy of Sciences of the United States of America (2012)

492 Citations

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