World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
125
Citations
58684
World Ranking
282
National Ranking
181

Medicine

D-Index
125
Citations
58692
World Ranking
3094
National Ranking
1709

Research.com Recognitions

  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Norman L. Letvin was affiliated with Beth Israel Deaconess Medical Center in the United States. Their research domains primarily encompassed Immunology and Microbiology and Medicine, with a significant focus on subfields including Virology, Immunology, Epidemiology, Emergency Medicine, and Infectious Diseases.

The scientist's scholarly output showcased a concentration on HIV research, immune responses, and herpesvirus infections. Main topics of their work included:

  • HIV Research and Treatment
  • Cytomegalovirus and herpesvirus research
  • HIV-related health complications and treatments
  • Interferon and immune responses
  • Immune Cell Function and Interaction
  • Herpesvirus Infections and Treatments
  • Immunotherapy and Immune Responses

Norman L. Letvin collaborated frequently with several researchers, notable among them:

  • Barton F. Haynes
  • Myron S. Cohen
  • Kathryn L. Furr
  • Michelle A. Lifton
  • Georgia D. Tomaras

The scientist published in various venues, with multiple contributions to UNC Libraries. Other frequent publication venues included:

  • Nature Immunology
  • PLoS Pathogens
  • npj Vaccines

Examples of recent papers authored or co-authored by Norman L. Letvin include:

  • "The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination," 2021, Nature Immunology
  • "Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes," 2021, PLoS Pathogens
  • "Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center," 2021, npj Vaccines
  • "Recurrent Signature Patterns in HIV-1 B Clade Envelope Glycoproteins Associated with either Early or Chronic Infections," 2021, UNC Libraries
  • "Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population," 2020, UNC Libraries

The scientist was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2006 and held membership in the Association of American Physicians. Norman L. Letvin is deceased.

Best Publications

  • Control of Viremia in Simian Immunodeficiency Virus Infection by CD8+ Lymphocytes

    Jörn E. Schmitz;Marcelo J. Kuroda;Sampa Santra;Vito G. Sasseville

  • Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity.

    John W. Shiver;Tong-Ming Fu;Ling Chen;Danilo R. Casimiro

  • A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1

    Jacques Fellay;Kevin V. Shianna;Dongliang Ge;Sara Colombo

  • Isolation of T-cell tropic HTLV-III-like retrovirus from macaques

    Daniel;NL Letvin;NW King;M Kannagi

  • Sexual transmission and propagation of SIV and HIV in resting and activated CD4+ T cells.

    Z. Q. Zhang;T. Schuler;M. Zupancic;Stephen W Wietgrefe

  • Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augmented DNA Vaccination

    Dan H. Barouch;Sampa Santra;Jörn E. Schmitz;Marcelo J. Kuroda

  • The isolation and characterization of the human suppressor inducer T cell subset.

    C Morimoto;N L Letvin;J A Distaso;W R Aldrich

  • Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

    Dan H. Barouch;Jennifer Kunstman;Marcelo J. Kuroda;Jörn E. Schmitz

  • The isolation and characterization of the human helper inducer T cell subset.

    C Morimoto;N L Letvin;A W Boyd;M Hagan

  • Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III

    N L Letvin;M D Daniel;P K Sehgal;R C Desrosiers

  • The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

    Nilu Goonetilleke;Michael K.P. Liu;Jesus F. Salazar-Gonzalez;Guido Ferrari

  • A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys.

    K A Reimann;J T Li;R Veazey;M Halloran

  • Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants.

    Will Fischer;Simon Perkins;James Theiler;Tanmoy Bhattacharya;Tanmoy Bhattacharya

  • Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys.

    Norman L. Letvin;John R. Mascola;Yue Sun;Darci A. Gorgone

  • Focal mycobacterial lymphadenitis following initiation of protease-inhibitor therapy in patients with advanced HIV-1 disease

    Elizabeth M Race;Jennifer Adelson-Mitty;Gila R Kriegel;Tamar F Barlam

  • Adaptive Immune Response of Vγ2Vδ2+ T Cells During Mycobacterial Infections

    Yun Shen;Dejiang Zhou;Liyou Qiu;Xioamin Lai

  • Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination.

    Norman L. Letvin;David C. Montefiori;Yasuhiro Yasutomi;Helen C. Perry

  • Immunogenicity of Recombinant Adenovirus Serotype 35 Vaccine in the Presence of Pre-Existing Anti-Ad5 Immunity

    Dan H. Barouch;Maria G. Pau;Jerome H. H. V. Custers;Wouter Koudstaal

  • Common genetic variation and the control of HIV-1 in humans.

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

  • Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

    Hua Xin Liao;Mattia Bonsignori;S. Munir Alam;Jason S. McLellan

  • Vaccine protection against simian immunodeficiency virus infection.

    R C Desrosiers;M S Wyand;T Kodama;D J Ringler

  • Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex.

    Marcelo J. Kuroda;Jörn E. Schmitz;Dan H. Barouch;Abie Craiu

  • Common Genetic Variation and the Control of HIV-1 in Humans

    Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

Frequent Co-Authors

Barton F. Haynes
Barton F. Haynes Duke University
Jörn E. Schmitz
Jörn E. Schmitz Harvard Medical School
Michelle A. Lifton
Michelle A. Lifton Beth Israel Deaconess Medical Center
David C. Montefiori
David C. Montefiori Duke University
Dan H. Barouch
Dan H. Barouch Harvard Medical School
Bette T. Korber
Bette T. Korber Los Alamos National Laboratory
Sampa Santra
Sampa Santra Beth Israel Deaconess Medical Center
Keith A. Reimann
Keith A. Reimann Harvard Medical School
Gary J. Nabel
Gary J. Nabel ModeX Therapeutics
John R. Mascola
John R. Mascola ModeX Therapeutics

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Best Scientists Citing Norman L. Letvin