World's Best Scientists 2026 revealed!
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Immunology
USA
2026

D-Index & Metrics

Immunology

D-Index
163
Citations
102518
World Ranking
70
National Ranking
48

Medicine

D-Index
163
Citations
102518
World Ranking
685
National Ranking
395

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2017 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

John R. Mascola is affiliated with ModeX Therapeutics in the United States and has contributed extensively to research in medicine, immunology, and microbiology. Their work spans multiple subfields including infectious diseases, virology, immunology, epidemiology, and radiology, nuclear medicine, and imaging.

The scientist's research covers a range of main topics such as HIV research and treatment, SARS-CoV-2 and COVID-19 research, monoclonal and polyclonal antibodies research, HIV/AIDS drug development and treatment, immune cell function and interaction, viral gastroenteritis research and epidemiology, and studies on animal virus infections.

Frequently publishing in venues recognized in the scientific community, John R. Mascola has contributed to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Science Translational Medicine
  • Cell Reports
  • Nature Communications

Their collaborative work includes frequent co-authorship with researchers such as Peter D. Kwong, Barney S. Graham, Nicole A. Doria-Rose, Tongqing Zhou, and Adrian B. McDermott.

Notable recent publications include:

  • An mRNA Vaccine against SARS-CoV-2 - Preliminary Report, 2020, New England Journal of Medicine
  • SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness, 2020, Nature
  • Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates, 2020, New England Journal of Medicine
  • Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination, 2020, New England Journal of Medicine
  • Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19, 2021, New England Journal of Medicine

John R. Mascola has been recognized with memberships in professional organizations including the National Academy of Medicine (NAM) since 2017 and the Association of American Physicians.

Best Publications

  • Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.

    Lindsey R. Baden;Hana M El Sahly;Brandon J Essink;Karen Kotloff

  • An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

    Lisa A. Jackson;Evan J. Anderson;Nadine G. Rouphael;Paul C. Roberts

  • Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.

    Pengfei Wang;Manoj S. Nair;Lihong Liu;Sho Iketani;Sho Iketani

  • Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

    Xueling Wu;Zhi Yong Yang;Yuxing Li;Carl Magnus Hogerkorp

  • Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies

    John R. Mascola;Gabriela Stiegler;Thomas C. VanCott;Hermann Katinger

  • SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

    Kizzmekia S. Corbett;Darin K. Edwards;Sarah R. Leist;Olubukola M. Abiona

  • Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.

    Tongqing Zhou;Ivelin Georgiev;Xueling Wu;Zhi Yong Yang

  • Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

    Ming Li;Feng Gao;John R. Mascola;Leonidas Stamatatos

  • Protection of Macaques against Pathogenic Simian/Human Immunodeficiency Virus 89.6PD by Passive Transfer of Neutralizing Antibodies

    John R. Mascola;Mark G. Lewis;Gabriela Stiegler;Dawn Harris

  • Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

    Hua-Xin Liao;Rebecca Lynch;Tongqing Zhou;Feng Gao;Feng Gao

  • Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates.

    Kizzmekia S Corbett;Barbara Flynn;Kathryn E Foulds;Joseph R Francica

  • Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

    Jason S. McLellan;Marie Pancera;Chris Carrico;Jason Gorman

  • Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

    Johannes F. Scheid;Hugo Mouquet;Niklas Feldhahn;Michael S. Seaman

  • Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

    Jinghe Huang;Gilad Ofek;Leo Laub;Mark K. Louder

  • Human skin Langerhans cells are targets of dengue virus infection.

    Shuenn-Jue L. Wu;Geraldine Grouard-Vogel;Wellington Sun;John R. Mascola

  • Structure and immune recognition of trimeric pre-fusion HIV-1 Env

    Marie Pancera;Tongqing Zhou;Aliaksandr Druz;Ivelin S. Georgiev

  • Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.

    Nicole A. Doria-Rose;Chaim A. Schramm;Jason Gorman;Penny L. Moore

  • Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination.

    Alicia T. Widge;Nadine G. Rouphael;Lisa A. Jackson;Evan J. Anderson

  • Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection

    Hadi M. Yassine;Jeffrey C. Boyington;Patrick M. McTamney;Patrick M. McTamney;Chih Jen Wei;Chih Jen Wei

  • Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies.

    Michael S. Seaman;Holly Janes;Natalie Hawkins;Lauren E. Grandpre

  • Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19.

    Nicole Doria-Rose;Mehul S. Suthar;Mat Makowski;Sarah O’Connell

  • Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization

    Pengfei Wang;Manoj S Nair;Lihong Liu;Sho Iketani;Sho Iketani

Frequent Co-Authors

Peter D. Kwong
Peter D. Kwong Columbia University Medical Center
Gary J. Nabel
Gary J. Nabel ModeX Therapeutics
Barney S. Graham
Barney S. Graham Morehouse School of Medicine
Mark K. Louder
Mark K. Louder National Institute of Allergy and Infectious Diseases
Sijy O'Dell
Sijy O'Dell National Institute of Allergy and Infectious Diseases
Robert T. Bailer
Robert T. Bailer National Institute of Allergy and Infectious Diseases
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
David C. Montefiori
David C. Montefiori Duke University
Nicole A. Doria-Rose
Nicole A. Doria-Rose National Institute of Allergy and Infectious Diseases
Tongqing Zhou
Tongqing Zhou National Institutes of Health

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