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Immunology

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Overview

Nelson L. Michael is affiliated with the Walter Reed Army Institute of Research in the United States. Their research primarily focuses on infectious diseases, with significant contributions to medicine, immunology, and microbiology. Their work spans various subfields including infectious diseases, virology, immunology, epidemiology, and public health.

Their scientific output addresses multiple main topics such as HIV research and treatment, SARS-CoV-2 and COVID-19 research, immune cell function and interaction, HIV/AIDS interventions, T-cell and B-cell immunology, COVID-19 clinical studies, and animal virus infection studies.

Among their recent publications are:

  • "SARS-CoV-2 Variants in Patients with Immunosuppression" (2021, New England Journal of Medicine)
  • "A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants" (2020, Proceedings of the National Academy of Sciences)
  • "SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity" (2021, Cell Reports)
  • "A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates" (2022, Science Translational Medicine)
  • "Accelerating Development of SARS-CoV-2 Vaccines - The Role for Controlled Human Infection Models" (2020, New England Journal of Medicine)

Frequent collaborators include Merlin L. Robb, Sandhya Vasan, Kayvon Modjarrad, Shelly J. Krebs, and Sodsai Tovanabutra. These coauthors have contributed extensively to related research topics alongside Michael.

Their work has been published extensively in several venues related to infectious diseases and vaccine research. Notable frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • npj Vaccines
  • EBioMedicine
  • Journal of Virology

Michael's research integrates immunology and microbiology to explore disease mechanisms, vaccine development, and immune response modulation. The scientist's contributions to SARS-CoV-2 and HIV research reflect a broad and interdisciplinary approach to addressing global infectious health threats.

Best Publications

  • Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

    Supachai Rerks-Ngarm;Punnee Pitisuttithum;Sorachai Nitayaphan;Jaranit Kaewkungwal

  • Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

    Barton F. Haynes;Peter B. Gilbert;M. Juliana McElrath;Susan Zolla-Pazner

  • Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

    James B. Whitney;Alison L. Hill;Srisowmya Sanisetty;Pablo Penaloza-MacMaster

  • Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection

    Victor Valcour;Thep Chalermchai;Napapon Sailasuta;Mary Marovich

  • The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression

    N. L. Michael;G. Chang;L. G. Louie;J. R. Mascola

  • Vaccine protection against Zika virus from Brazil

    Rafael A. Larocca;Peter Abbink;Jean Pierre S. Peron;Paolo M. de A. Zanotto

  • GENETIC ACCELERATION OF AIDS PROGRESSION BY A PROMOTER VARIANT OF CCR5

    Maureen P. Martin;Michael Dean;Michael W. Smith;Cheryl Winkler

  • Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

    Peter Abbink;Rafael A. Larocca;Rafael A. De La Barrera;Christine A. Bricault

  • Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

    Dan H. Barouch;Dan H. Barouch;Jinyan Liu;Hualin Li;Lori F. Maxfield

  • Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2

    Morgane Rolland;Paul T. Edlefsen;Brendan B. Larsen;Sodsai Tovanabutra

  • Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination

    Nicole L. Yates;Nicole L. Yates;Hua Xin Liao;Hua Xin Liao;Youyi Fong;Allan DeCamp

  • A Recombinant Vesicular Stomatitis Virus Ebola Vaccine — Preliminary Report

    Jason A. Regules;John H. Beigel;Kristopher M. Paolino;Jocelyn Voell

  • Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family

    Mattia Bonsignori;Justin Pollara;M. Anthony Moody;Michael D. Alpert

  • Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG

    Georgia D. Tomaras;Guido Ferrari;Xiaoying Shen;S. Munir Alam

  • Polyfunctional Fc-Effector Profiles Mediated by IgG Subclass Selection Distinguish RV144 and VAX003 Vaccines

    Amy W. Chung;Musie Ghebremichael;Hannah Robinson;Eric Brown

  • SARS-CoV-2 Variants in Patients with Immunosuppression.

    Lawrence Corey;Chris Beyrer;Myron S Cohen;Nelson L Michael

  • Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

    Hua Xin Liao;Mattia Bonsignori;S. Munir Alam;Jason S. McLellan

  • Influence of HLA-C Expression Level on HIV Control

    Richard Apps;Richard Apps;Ying Qi;Ying Qi;Jonathan M. Carlson;Haoyan Chen;Haoyan Chen

  • Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data

    J. P.A. Ioannidis;P. S. Rosenberg;J. J. Goedert;L. J. Ashton

  • Protective Efficacy of a Global HIV-1 Mosaic Vaccine against Heterologous SHIV Challenges in Rhesus Monkeys

    Dan H. Barouch;Dan H. Barouch;Kathryn E. Stephenson;Erica N. Borducchi;Kaitlin Smith

  • Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.

    Amy W. Chung;Amy W. Chung;Manu P. Kumar;Kelly B. Arnold;Wen Han Yu;Wen Han Yu

  • Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

    David C. Montefiori;Chitraporn Karnasuta;Ying Huang;Hasan Ahmed

  • HIV-1 infection in a man homozygous for CCR5▵32

    Thomas R O'Brien;Cheryl Winkler;Michael Dean;Julie Ae Nelson

Frequent Co-Authors

Merlin L. Robb
Merlin L. Robb Walter Reed Army Institute of Research
Jerome H. Kim
Jerome H. Kim Walter Reed Army Institute of Research
Sorachai Nitayaphan
Sorachai Nitayaphan Armed Forces Research Institute of Medical Science
Punnee Pitisuttithum
Punnee Pitisuttithum Mahidol University
Dan H. Barouch
Dan H. Barouch Harvard Medical School
David C. Montefiori
David C. Montefiori Duke University
Morgane Rolland
Morgane Rolland Henry M. Jackson Foundation
Georgia D. Tomaras
Georgia D. Tomaras Duke University
Barton F. Haynes
Barton F. Haynes Duke University
Victoria R. Polonis
Victoria R. Polonis Walter Reed Army Institute of Research

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