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Overview

Victoria R. Polonis is affiliated with the Walter Reed Army Institute of Research in the United States. Their research spans multiple disciplines within medicine and immunology, particularly focusing on infectious diseases and virology.

The primary fields of study for Victoria R. Polonis include Medicine and Immunology and Microbiology, with notable contributions in the subfields of Infectious Diseases, Virology, Immunology, Molecular Biology, and Epidemiology.

The main topics addressed in their research cover HIV Research and Treatment, SARS-CoV-2 and COVID-19 Research, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Monoclonal and Polyclonal Antibodies Research, COVID-19 Clinical Research Studies, and SARS-CoV-2 detection and testing.

Their recent publications demonstrate a focus on vaccine development and immune response to viral infections. Selected papers include:

  • SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity, 2021, Cell Reports
  • A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates, 2022, Science Translational Medicine
  • Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption, 2020, Nature Medicine
  • A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge, 2021, npj Vaccines
  • Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques, 2021, Proceedings of the National Academy of Sciences

Frequent co-authors who have collaborated with Victoria R. Polonis include Lindsay Wieczorek, Nelson L. Michael, Shelly J. Krebs, Michelle Zemil, and Vincent Dussupt.

Their work has been published regularly in specific scientific venues, reflecting an ongoing engagement with the immunology and virology research communities. Common publication venues include bioRxiv (Cold Spring Harbor Laboratory), PLoS Pathogens, Frontiers in Immunology, Nature Communications, and Journal of Virology.

Best Publications

  • Human Immunodeficiency Virus Type 1 env Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

    Ming Li;Feng Gao;John R. Mascola;Leonidas Stamatatos

  • Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies.

    Michael S. Seaman;Holly Janes;Natalie Hawkins;Lauren E. Grandpre

  • Genetic and Neutralization Properties of Subtype C Human Immunodeficiency Virus Type 1 Molecular env Clones from Acute and Early Heterosexually Acquired Infections in Southern Africa

    Ming Li;Jesus F. Salazar-Gonzalez;Cynthia A. Derdeyn;Lynn Morris

  • Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

    David C. Montefiori;Chitraporn Karnasuta;Ying Huang;Hasan Ahmed

  • Recommendations for the design and use of standard virus panels to assess neutralizing antibody responses elicited by candidate human immunodeficiency virus type 1 vaccines.

    John R. Mascola;Patricia D'Souza;Peter Gilbert;Beatrice H. Hahn

  • A Phase I Evaluation of the Safety and Immunogenicity of Vaccination with Recombinant gp160 in Patients with Early Human Immunodeficiency Virus Infection

    Redfield Rr;Birx Dl;Ketter N;Tramont E

  • Human Monoclonal Antibodies Specific for Conformation-Sensitive Epitopes of V3 Neutralize Human Immunodeficiency Virus Type 1 Primary Isolates from Various Clades

    Miroslaw K. Gorny;Constance Williams;Barbara Volsky;Kathy Revesz

  • Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC

    Tar A. G. Edmonds;Haitao Ding;Xing Yuan;Qing Wei

  • A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

    Unknown

  • Biologic and Genetic Characterization of a Panel of 60 Human Immunodeficiency Virus Type 1 Isolates, Representing Clades A, B, C, D, CRF01_AE, and CRF02_AG, for the Development and Assessment of Candidate Vaccines

    Bruce K. Brown;Janice M. Darden;Sodsai Tovanabutra;Tamara Oblander

  • Safety and immunogenicity of an HIV subtype B and E prime-boost vaccine combination in HIV-negative Thai adults

    Sorachai Nitayaphan;Punnee Pitisuttithum;Chitraporn Karnasuta;Chirapa Eamsila

  • Recent advances in the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination.

    Victoria R. Polonis;Bruce K. Brown;Andrew Rosa Borges;Susan Zolla-Pazner

  • Development of Calibrated Viral Load Standards for Group M Subtypes of Human Immunodeficiency Virus Type 1 and Performance of an Improved AMPLICOR HIV-1 MONITOR Test with Isolates of Diverse Subtypes

    Nelson L. Michael;Steven A. Herman;Shirley Kwok;Kimberly Dreyer

  • SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

    Unknown

  • Differential role of V3-specific antibodies in neutralization assays involving primary and laboratory-adapted isolates of HIV type 1

    T.C. Vancott;V.R. Polonis;L.D. Loomis;N.L. Michael

  • Dissociation rate of antibody-gp120 binding interactions is predictive of V3-mediated neutralization of HIV-1.

    T C VanCott;F R Bethke;V R Polonis;M K Gorny

  • International network for comparison of HIV neutralization assays: the NeutNet report.

    Eva Maria Fenyö;Alan Heath;Stefania Dispinseri;Harvey Holmes

  • A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine: ALVAC-HIV (vCP1521) prime with oligomeric gp160 (92TH023/LAI-DID) or bivalent gp120 (CM235/SF2) boost.

    Prasert Thongcharoen;Vinai Suriyanon;Robert M Paris;Chirasak Khamboonruang

  • Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1.

    Shengqiang Li;Victoria Polonis;Hidecki Isobe;Habib Zaghouani

  • Cross-clade neutralization patterns among HIV-1 strains from the six major clades of the pandemic evaluated and compared in two different models.

    Bruce K. Brown;Lindsay Wieczorek;Eric Sanders-Buell;Andrew Rosa Borges

  • Broad and potent immune responses to a low dose intradermal HIV-1 DNA boosted with HIV-1 recombinant MVA among healthy adults in Tanzania.

    Muhammad Bakari;Said Aboud;Said Aboud;Charlotta Nilsson;Joel Francis

  • In-Depth Analysis of a Heterosexually Acquired Human Immunodeficiency Virus Type 1 Superinfection: Evolution, Temporal Fluctuation, and Intercompartment Dynamics from the Seronegative Window Period through 30 Months Postinfection

    F. E. McCutchan;M. Hoelscher;S. Tovanabutra;S. Piyasirisilp

Frequent Co-Authors

Nelson L. Michael
Nelson L. Michael Walter Reed Army Institute of Research
David C. Montefiori
David C. Montefiori Duke University
Merlin L. Robb
Merlin L. Robb Walter Reed Army Institute of Research
Deborah L. Birx
Deborah L. Birx Centers for Disease Control and Prevention
Jerome H. Kim
Jerome H. Kim Walter Reed Army Institute of Research
Carl R. Alving
Carl R. Alving Walter Reed Army Institute of Research
M. Gordon Joyce
M. Gordon Joyce Henry M. Jackson Foundation
Alexander R. A. Anderson
Alexander R. A. Anderson Moffitt Cancer Center
Morgane Rolland
Morgane Rolland Henry M. Jackson Foundation
John C. Kappes
John C. Kappes University of Alabama at Birmingham

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