His primary areas of investigation include Virology, Virus, Viral replication, Antibody and Molecular biology. John C. Kappes studies Viral disease, a branch of Virology. His research on Virus often connects related topics like Gp41.
His Viral replication research is multidisciplinary, incorporating elements of Genome and Glycoprotein. His studies in Molecular biology integrate themes in fields like Mutation, Mutant protein, Codon usage bias, Protein folding and Messenger RNA. His Viral entry study combines topics from a wide range of disciplines, such as Wild type, Enfuvirtide and Viral load.
His main research concerns Virology, Virus, Antibody, Molecular biology and Immunology. His Virology study combines topics in areas such as Reverse transcriptase and Fusion protein. His biological study deals with issues like Glycoprotein, which deal with fields such as Gp41.
The Antibody study combines topics in areas such as Peripheral blood mononuclear cell and Antigen. His research in Molecular biology intersects with topics in Cell culture, Recombinant DNA, Mutant, Messenger RNA and Cell biology. The concepts of his Immunology study are interwoven with issues in Cytotoxic T cell and In vivo.
The scientist’s investigation covers issues in Virology, Glycoprotein, Immunology, Antibody and Cell biology. John C. Kappes has researched Virology in several fields, including Genetically modified mouse and Antibody-dependent cell-mediated cytotoxicity. He combines subjects such as Infectivity, Gp41 and Golgi apparatus with his study of Glycoprotein.
His study in Immunology is interdisciplinary in nature, drawing from both Cell culture and Transgene. His Antibody research integrates issues from Humanized mouse, In vivo and Antigen. His Virus research is multidisciplinary, incorporating perspectives in Consensus sequence, Dendritic cell and Flow cytometry.
John C. Kappes spends much of his time researching Immunology, Antibody, Virology, Epitope and In vivo. His work in Immunology covers topics such as Cell culture which are related to areas like NADPH Oxidase 1, Molecular biology, NADPH oxidase complex and Cell growth. His Antibody research incorporates elements of Downregulation and upregulation, Gene, NKG2D, Reporter gene and Cell biology.
A large part of his Virology studies is devoted to Virus latency. His research integrates issues of Glycosylation, Glycoprotein, Glycan, Virus and Peptide sequence in his study of Epitope. His study in Virus focuses on Neutralizing antibody in particular.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Antibody neutralization and escape by HIV-1
Xiping Wei;Julie M. Decker;Shuyi Wang;Huxiong Hui.
Nature (2003)
Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy
Xiping Wei;Julie M. Decker;Hongmei Liu;Zee Zhang.
Antimicrobial Agents and Chemotherapy (2002)
High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR
Piatak M;Saag Ms;Yang Lc;Clark Sj.
Science (1993)
High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection.
Stephen J. Clark;Michael S. Saag;W. Don Decker;Sherri Campbell-Hill.
The New England Journal of Medicine (1991)
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.
Jesus F. Salazar-Gonzalez;Maria G. Salazar;Brandon F. Keele;Gerald H. Learn.
Journal of Experimental Medicine (2009)
Sensitivity of Human Immunodeficiency Virus Type 1 to the Fusion Inhibitor T-20 Is Modulated by Coreceptor Specificity Defined by the V3 Loop of gp120
Cynthia A. Derdeyn;Julie M. Decker;Jeffrey N. Sfakianos;Xiaoyun Wu.
Journal of Virology (2000)
Oxidative Stress Induces Vascular Calcification Through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling
Chang Hyun Byon;Amjad Javed;Qun Dai;John C. Kappes.
Journal of Biological Chemistry (2008)
Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function
Cunren Liu;Shaohua Yu;Kurt Zinn;Jianhua Wang.
Journal of Immunology (2006)
Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes.
Yuexia Li;J. C. Kappes;J. A. Conway;R. W. Price.
Journal of Virology (1991)
Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains
Daniel Sauter;Michael Schindler;Anke Specht;Wilmina N. Landford.
Cell Host & Microbe (2009)
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