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Immunology

D-Index
72
Citations
25779
World Ranking
2178
National Ranking
1057

Overview

John C. Kappes is affiliated with the University of Alabama at Birmingham in the United States. Their research focuses primarily on medical and immunological fields, with a particular emphasis on HIV research and treatment.

The main fields of study in Kappes's work include:

  • Medicine
  • Immunology and Microbiology

They have contributed notably to several subfields such as:

  • Virology
  • Infectious Diseases
  • Molecular Biology
  • Immunology
  • Radiology, Nuclear Medicine and Imaging

The key research topics covered by their publications include:

  • HIV Research and Treatment
  • Monoclonal and Polyclonal Antibodies Research
  • HIV/AIDS drug development and treatment
  • Bacteriophages and microbial interactions
  • Cystic Fibrosis Research Advances
  • Immune Cell Function and Interaction
  • HIV/AIDS Research and Interventions

John C. Kappes has published extensively in several scientific venues, with a significant number of papers appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Nature Communications
  • Journal of Cystic Fibrosis
  • UNC Libraries

Their recent papers include:

  • Spike Glycoprotein and Host Cell Determinants of SARS-CoV-2 Entry and Cytopathic Effects (2020), Journal of Virology
  • Long-Acting BMS-378806 Analogues Stabilize the State-1 Conformation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins (2020), Journal of Virology
  • Dual Pathways of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trafficking Modulate the Selective Exclusion of Uncleaved Oligomers from Virions (2020), Journal of Virology
  • In vivo killing of primary HIV-infected cells by peripheral-injected early memory-enriched anti-HIV duoCAR T cells (2022), JCI Insight
  • Spike glycoprotein and host cell determinants of SARS-CoV-2 entry and cytopathic effects (2020), bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors working alongside Kappes include:

  • Joseph Sodroski
  • Shijian Zhang
  • Haitao Ding
  • Hanh T. Nguyen
  • Saumya Anang

Best Publications

  • Antibody neutralization and escape by HIV-1

    Xiping Wei;Julie M. Decker;Shuyi Wang;Huxiong Hui

  • Emergence of Resistant Human Immunodeficiency Virus Type 1 in Patients Receiving Fusion Inhibitor (T-20) Monotherapy

    Xiping Wei;Julie M. Decker;Hongmei Liu;Zee Zhang

  • High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR

    Piatak M;Saag Ms;Yang Lc;Clark Sj

  • High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection.

    Stephen J. Clark;Michael S. Saag;W. Don Decker;Sherri Campbell-Hill

  • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection.

    Jesus F. Salazar-Gonzalez;Maria G. Salazar;Brandon F. Keele;Gerald H. Learn

  • Sensitivity of Human Immunodeficiency Virus Type 1 to the Fusion Inhibitor T-20 Is Modulated by Coreceptor Specificity Defined by the V3 Loop of gp120

    Cynthia A. Derdeyn;Julie M. Decker;Jeffrey N. Sfakianos;Xiaoyun Wu

  • Oxidative Stress Induces Vascular Calcification Through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

    Chang Hyun Byon;Amjad Javed;Qun Dai;John C. Kappes

  • Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function

    Cunren Liu;Shaohua Yu;Kurt Zinn;Jianhua Wang

  • Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes.

    Yuexia Li;J. C. Kappes;J. A. Conway;R. W. Price

  • Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

    Daniel Sauter;Michael Schindler;Anke Specht;Wilmina N. Landford

  • Phenotypic properties of transmitted founder HIV-1

    Nicholas F. Parrish;Feng Gao;Hui Li;Elena E. Giorgi

  • Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host

    Cunren Liu;Shaohua Yu;John Kappes;Jianhua Wang

  • Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of their Replication Capacity in CD4 T-Lymphocytes and Monocyte-derived Macrophages

    Christina Ochsenbauer;Tara G. Edmonds;Haitao Ding;Brandon F. Keele

  • Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells.

    Gang Meng;Xiping Wei;Xiaoyun Wu;Marty T. Sellers

  • Global Panel of HIV-1 Env Reference Strains for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

    Allan deCamp;Peter Hraber;Robert T. Bailer;Michael S. Seaman

  • Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

    David C. Montefiori;Chitraporn Karnasuta;Ying Huang;Hasan Ahmed

  • An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum

    Guido Ferrari;Justin Pollara;Daniel Kozink;Tiara Harms

  • Cytidine Deaminases APOBEC3G and APOBEC3F Interact with Human Immunodeficiency Virus Type 1 Integrase and Inhibit Proviral DNA Formation

    Kun Luo;Tao Wang;Bindong Liu;Chunjuan Tian

  • Human Immunodeficiency Virus Type 1 Integrase Protein Promotes Reverse Transcription through Specific Interactions with the Nucleoprotein Reverse Transcription Complex

    Xiaoyun Wu;Hongmei Liu;Hongling Xiao;Joan A. Conway

  • Staged induction of HIV-1 glycan–dependent broadly neutralizing antibodies

    Mattia Bonsignori;Mattia Bonsignori;Edward F. Kreider;Daniela Fera;R. Ryan Meyerhoff;R. Ryan Meyerhoff

  • Relative resistance of HIV-1 founder viruses to control by interferon-alpha.

    Angharad E Fenton-May;Oliver Dibben;Tanja Emmerich;Haitao Ding

Frequent Co-Authors

George M. Shaw
George M. Shaw University of Pennsylvania
Beatrice H. Hahn
Beatrice H. Hahn University of Pennsylvania
David C. Montefiori
David C. Montefiori Duke University
Barton F. Haynes
Barton F. Haynes Duke University
Victoria R. Polonis
Victoria R. Polonis Walter Reed Army Institute of Research
Georgia D. Tomaras
Georgia D. Tomaras Duke University
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Guido Ferrari
Guido Ferrari Duke University
Julie M. Decker
Julie M. Decker University of Alabama at Birmingham
Nelson L. Michael
Nelson L. Michael Walter Reed Army Institute of Research

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Related Online Degrees & Career Pathways

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Understanding the financial outlook is equally important. The doctor of nursing practice salary varies by state and specialization, highlighting promising earning potential for those who advance their education and focus on immunology or related acute care fields.

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