His main research concerns Glycoprotein, Virology, Antibody, Antibody-dependent cell-mediated cytotoxicity and Cell. His work deals with themes such as Biophysics, Gp41, Transmembrane protein, HEK 293 cells and Protein structure, which intersect with Glycoprotein. His Virology research incorporates themes from Plasma protein binding, Endocytosis and Maraviroc.
Immunology covers Andrés Finzi research in Antibody. His Antibody-dependent cell-mediated cytotoxicity study combines topics in areas such as Flow cytometry and Effector. His Cell study combines topics from a wide range of disciplines, such as Infectivity, Viral load, Function and In vivo.
His primary scientific interests are in Antibody, Virology, Antibody-dependent cell-mediated cytotoxicity, Glycoprotein and Epitope. In the subject of general Antibody, his work in Neutralization is often linked to Severe acute respiratory syndrome coronavirus 2, thereby combining diverse domains of study. His Virology study integrates concerns from other disciplines, such as Flow cytometry and Recombinant DNA.
His research integrates issues of Downregulation and upregulation, Immune system, Molecular biology and Effector, Cell biology in his study of Antibody-dependent cell-mediated cytotoxicity. His work carried out in the field of Glycoprotein brings together such families of science as Biophysics, Viral entry, Gp41 and Plasma protein binding. His Epitope research includes themes of In vitro, Cytotoxicity, Vaccine trial and CD4 antigen.
Andrés Finzi mostly deals with Antibody, Virology, Severe acute respiratory syndrome coronavirus 2, Immunology and Neutralization. His biological study spans a wide range of topics, including Virus and Glycoprotein. His research on Glycoprotein also deals with topics like
His Neutralization research incorporates elements of Titer, Monoclonal antibody, Immunoglobulin G and Recombinant DNA. His studies deal with areas such as Small molecule and Binding site as well as Antibody-dependent cell-mediated cytotoxicity. His study in Epitope is interdisciplinary in nature, drawing from both In vivo and Effector.
The scientist’s investigation covers issues in Antibody, Severe acute respiratory syndrome coronavirus 2, Immunology, Neutralization and Convalescent plasma. His work in Antibody is not limited to one particular discipline; it also encompasses Glycoprotein. The study incorporates disciplines such as Virus, Hiv 1 envelope and Cell biology in addition to Glycoprotein.
His studies in Virus integrate themes in fields like Cell, Biophysics, Receptor and Antibody-dependent cell-mediated cytotoxicity. When carried out as part of a general Immunology research project, his work on Antibody titer is frequently linked to work in Coronavirus, therefore connecting diverse disciplines of study. His Neutralization research integrates issues from Titer and Immunoglobulin G.
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Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.
Tongqing Zhou;Ivelin Georgiev;Xueling Wu;Zhi Yong Yang.
Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops
Young Do Kwon;Andrés Finzi;Xueling Wu;Cajetan Dogo-Isonagie.
Proceedings of the National Academy of Sciences of the United States of America (2012)
Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions
Andrés Finzi;Shi Hua Xiang;Beatriz Pacheco;Liping Wang.
Molecular Cell (2010)
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase.
Jean-Philippe Belzile;Ghislaine Duisit;Nicole Rougeau;Johanne Mercier.
PLOS Pathogens (2007)
Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity
Maxime Veillette;Anik Désormeaux;Halima Medjahed;Nour-Elhouda Gharsallah.
Journal of Virology (2014)
A B-Box 2 Surface Patch Important for TRIM5α Self-Association, Capsid Binding Avidity, and Retrovirus Restriction
Felipe Diaz-Griffero;Xu Rong Qin;Fumiaki Hayashi;Takanori Kigawa.
Journal of Virology (2009)
Macrophage Infection via Selective Capture of HIV-1-Infected CD4+ T Cells
Amy E. Baxter;Amy E. Baxter;Rebecca A. Russell;Christopher J.A. Duncan;Michael D. Moore.
Cell Host & Microbe (2014)
The HIV-1 gp120 CD4-Bound Conformation Is Preferentially Targeted by Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Sera from HIV-1-Infected Individuals
Maxime Veillette;Mathieu Coutu;Jonathan Richard;Laurie-Anne Batraville.
Journal of Virology (2015)
Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals
Amy E. Baxter;Julia Niessl;Rémi Fromentin;Jonathan Richard.
Cell Host & Microbe (2016)
Productive Human Immunodeficiency Virus Type 1 Assembly Takes Place at the Plasma Membrane
Andrés Finzi;Alexandre Orthwein;Johanne Mercier;Éric A. Cohen.
Journal of Virology (2007)
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