Daniel Kaufmann

Best Publications

• PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

  Cheryl L Day;Daniel E Kaufmann;Photini Kiepiela;Julia A Brown

  3248
  Citations

• Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.

  Daniel E Kaufmann;Daniel G Kavanagh;Florencia Pereyra;Florencia Pereyra;John J Zaunders

  676
  Citations

• AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV Cohort Study.

  Bruno Ledergerber;M. Egger;V. Erard;R. Weber

  664
  Citations

• Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

  Florencia Pereyra;Marylyn M. Addo;Daniel E. Kaufmann;Yang Liu

  655
  Citations

• Transcriptional analysis of HIV-specific CD8 + T cells shows that PD-1 inhibits T cell function by upregulating BATF

  Michael Quigley;Florencia Pereyra;Björn Nilsson;Filippos Porichis

  600
  Citations

• A Blueprint for HIV Vaccine Discovery

  Dennis R. Burton;Rafi Ahmed;Rafi Ahmed;Dan H. Barouch;Dan H. Barouch;Dan H. Barouch;Salvatore T. Butera

  459
  Citations

• Loss of HIV-1–specific CD8+ T Cell Proliferation after Acute HIV-1 Infection and Restoration by Vaccine-induced HIV-1–specific CD4+ T Cells

  Mathias Lichterfeld;Daniel E. Kaufmann;Xu G. Yu;Stanley K. Mui

  445
  Citations

• CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART)

  Daniel Kaufmann;Giuseppe Pantaleo;Philippe Sudre;Amalio Telenti

  398
  Citations

• CXCL13 is a plasma biomarker of germinal center activity

  Colin Havenar-Daughton;Madelene Lindqvist;Antje Heit;Jennifer E. Wu

  351
  Citations

• Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution

  Todd M. Allen;Marcus Altfeld;Shaun C. Geer;Elizabeth T. Kalife

  346
  Citations

• IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.

  Mark A. Brockman;Mark A. Brockman;Douglas S. Kwon;Douglas S. Kwon;Douglas S. Kwon;Daniel P. Tighe;David F. Pavlik

  333
  Citations

• Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

  Samantha Reiss;Amy E. Baxter;Kimberly M. Cirelli;Jennifer M. Dan;Jennifer M. Dan

  326
  Citations

• TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

  Huabiao Chen;Zaza M Ndhlovu;Zaza M Ndhlovu;Dongfang Liu;Lindsay C Porter

  308
  Citations

• Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity

  Maxime Veillette;Anik Désormeaux;Halima Medjahed;Nour-Elhouda Gharsallah

  298
  Citations

• PD-1 and CTLA-4 Inhibitory Cosignaling Pathways in HIV Infection and the Potential for Therapeutic Intervention

  Daniel E. Kaufmann;Bruce D. Walker

  293
  Citations

• A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity.

  Sirui Zhou;Guillaume Butler-Laporte;Tomoko Nakanishi;David R. Morrison

  278
  Citations

• Limited durability of viral control following treated acute HIV infection.

  Daniel E Kaufmann;Mathias Lichterfeld;Marcus Altfeld;Marylyn M Addo

  249
  Citations

• The HIV-1 gp120 CD4-Bound Conformation Is Preferentially Targeted by Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Sera from HIV-1-Infected Individuals

  Maxime Veillette;Mathieu Coutu;Jonathan Richard;Laurie-Anne Batraville

  220
  Citations

• Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

  Marion Pardons;Amy E. Baxter;Marta Massanella;Amélie Pagliuzza

  215
  Citations

• Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy.

  Irfan Ullah;Jérémie Prévost;Mark S. Ladinsky;Helen Stone

  207
  Citations