Mark A. Brockman

Research.com Recognitions

• 1963 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.

  Daniel E Kaufmann;Daniel G Kavanagh;Florencia Pereyra;Florencia Pereyra;John J Zaunders

  676
  Citations

• Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.

  Arne Schneidewind;Mark A. Brockman;Mark A. Brockman;Ruifeng Yang;Rahma I. Adam

  392
  Citations

• IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells.

  Mark A. Brockman;Mark A. Brockman;Douglas S. Kwon;Douglas S. Kwon;Douglas S. Kwon;Daniel P. Tighe;David F. Pavlik

  333
  Citations

• Escape and Compensation from Early HLA-B57-Mediated Cytotoxic T-Lymphocyte Pressure on Human Immunodeficiency Virus Type 1 Gag Alter Capsid Interactions with Cyclophilin A

  Mark A. Brockman;Arne Schneidewind;Matthew Lahaie;Aaron Schmidt;Aaron Schmidt

  323
  Citations

• TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

  Huabiao Chen;Zaza M Ndhlovu;Zaza M Ndhlovu;Dongfang Liu;Lindsay C Porter

  308
  Citations

• HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphocyte Recognition.

  Toshiyuki Miura;Mark A. Brockman;Arne Schneidewind;Michael Lobritz

  294
  Citations

• Herpes simplex virus.

  Travis J Taylor;Mark A Brockman;Elizabeth E McNamee;David M Knipe

  230
  Citations

• HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

  Zabrina L. Brumme;Zabrina L. Brumme;Mina John;Jonathan M. Carlson;Chanson J. Brumme

  200
  Citations

• Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

  Filippos Porichis;Douglas S. Kwon;Douglas S. Kwon;Douglas S. Kwon;Jennifer Zupkosky;Daniel P. Tighe

  197
  Citations

• Structural and Functional Constraints Limit Options for Cytotoxic T-Lymphocyte Escape in the Immunodominant HLA-B27-Restricted Epitope in Human Immunodeficiency Virus Type 1 Capsid

  Arne Schneidewind;Mark A. Brockman;Mark A. Brockman;John Sidney;Yaoyu E. Wang

  189
  Citations

• HIV Increases HCV Replication in a TGF-β1–Dependent Manner

  Wenyu Lin;Ethan M. Weinberg;Andrew W. Tai;Lee F. Peng

  180
  Citations

• Reduced Magnitude and Durability of Humoral Immune Responses to COVID-19 mRNA Vaccines Among Older Adults

  Unknown

  173
  Citations

• Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection

  Mark A. Brockman;Mark A. Brockman;Mark A. Brockman;Zabrina L. Brumme;Zabrina L. Brumme;Zabrina L. Brumme;Chanson J. Brumme;Chanson J. Brumme;Toshiyuki Miura;Toshiyuki Miura

  161
  Citations

• Attenuation of multiple Nef functions in HIV-1 elite controllers.

  Philip Mwimanzi;Philip Mwimanzi;Tristan J Markle;Eric Martin;Yoko Ogata

  160
  Citations

• HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1

  Toshiyuki Miura;Mark A. Brockman;Zabrina L. Brumme;Chanson J. Brumme

  159
  Citations

• Genetic Characterization of Human Immunodeficiency Virus Type 1 in Elite Controllers: Lack of Gross Genetic Defects or Common Amino Acid Changes

  Toshiyuki Miura;Mark A. Brockman;Chanson J. Brumme;Zabrina L. Brumme

  158
  Citations

• Humoral response to herpes simplex virus is complement-dependent

  Xavier J. Da Costa;Mark A. Brockman;Elisabeth Alicot;Minghe Ma

  156
  Citations

• HIV-1 Vpu Mediates HLA-C Downregulation.

  Richard Apps;Gregory Q. Del Prete;Pramita Chatterjee;Abigail Lara

  154
  Citations

• Impaired Replication Capacity of Acute/Early Viruses in Persons Who Become HIV Controllers

  Toshiyuki Miura;Zabrina L. Brumme;Mark A. Brockman;Pamela Rosato

  153
  Citations

• Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy

  Unknown

  153
  Citations

• Selective Depletion of High-Avidity Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T Cells after Early HIV-1 Infection

  Mathias Lichterfeld;Xu G. Yu;Stanley K. Mui;Katie L. Williams

  140
  Citations

• HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte recognition (Journal of Virology (2009) 83, 6, (2743-2755))

  Toshiyuki Miura;Mark A. Brockman;Arne Schneidewind;Michael Lobritz

  14
  Citations