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Zabrina L. Brumme

Zabrina L. Brumme

D-Index & Metrics

Immunology

D-Index
61
Citations
14200
World Ranking
3223
National Ranking
79

Overview

Zabrina L. Brumme is affiliated with Simon Fraser University in Canada and has a focused research portfolio primarily in medicine and immunology and microbiology. Their work extensively covers infectious diseases, virology, immunology, molecular biology, and epidemiology.

The scientist's research topics prominently include:

  • HIV Research and Treatment
  • HIV/AIDS drug development and treatment
  • SARS-CoV-2 and COVID-19 Research
  • HIV/AIDS Research and Interventions
  • COVID-19 Clinical Research Studies
  • Immune Cell Function and Interaction
  • Vaccine Coverage and Hesitancy

Frequent publication venues for their work are diverse, with the majority of publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • AIDS
  • The Journal of Infectious Diseases
  • Nature Medicine

Notable recent papers authored or coauthored by Brumme include:

  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021 (2021, Nature Medicine)
  • Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial (2022, Nature Medicine)
  • Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results (2020, The Journal of Infectious Diseases)
  • Reduced Magnitude and Durability of Humoral Immune Responses to COVID-19 mRNA Vaccines Among Older Adults (2021, The Journal of Infectious Diseases)
  • HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA) (2021, Nature Communications)

Brumme frequently collaborates with multiple researchers, including:

  • Chanson J. Brumme
  • Mark A. Brockman
  • Winnie Dong
  • Julio Montaner
  • Marc G. Romney

Their contributions span 162 publications in medicine and 88 in immunology and microbiology, reflecting a strong interdisciplinary approach focused on viral infectious diseases, particularly HIV and COVID-19.

Best Publications

  • Changes in Mitochondrial DNA as a Marker of Nucleoside Toxicity in HIV-Infected Patients

    Hélène C F Côté;Zabrina L Brumme;Kevin J P Craib;Christopher S Alexander

  • Predictors of HIV Drug-Resistance Mutations in a Large Antiretroviral-Naive Cohort Initiating Triple Antiretroviral Therapy

    P. Richard Harrigan;Robert S. Hogg;Winnie W. Y. Dong;Benita Yip

  • Adaptation of HIV-1 to human leukocyte antigen class I

    Y. Kawashima;K. Pfafferott;J. Frater;P. Matthews

  • Influence of HLA-C Expression Level on HIV Control

    Richard Apps;Richard Apps;Ying Qi;Ying Qi;Jonathan M. Carlson;Haoyan Chen;Haoyan Chen

  • Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

    Matthew R. Henn;Christian L. Boutwell;Patrick Charlebois;Niall J Lennon

  • Molecular and Clinical Epidemiology of CXCR4-Using HIV-1 in a Large Population of Antiretroviral-Naive Individuals

    Zabrina L. Brumme;Zabrina L. Brumme;James Goodrich;Howard B. Mayer;Chanson J. Brumme

  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021.

    Steven G. Deeks;Nancie Archin;Paula Cannon;Simon Collins

  • Antigen Load and Viral Sequence Diversification Determine the Functional Profile of HIV-1–Specific CD8+ T Cells

    Hendrik Streeck;Zabrina L Brumme;Michael P. Anastario;Kristin W Cohen

  • TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection

    Huabiao Chen;Zaza M Ndhlovu;Zaza M Ndhlovu;Dongfang Liu;Lindsay C Porter

  • HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphocyte Recognition.

    Toshiyuki Miura;Mark A. Brockman;Arne Schneidewind;Michael Lobritz

  • Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

    Soo Yon Rhee;Jose Luis Blanco;Michael R. Jordan;Jonathan Taylor

  • Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

    Zabrina L Brumme;Zabrina L Brumme;Zabrina L Brumme;Chanson J Brumme;Chanson J Brumme;David Heckerman;Bette T Korber;Bette T Korber

  • Marked Epitope- and Allele-Specific Differences in Rates of Mutation in Human Immunodeficiency Type 1 (HIV-1) Gag, Pol, and Nef Cytotoxic T-Lymphocyte Epitopes in Acute/Early HIV-1 Infection

    Zabrina L. Brumme;Chanson J. Brumme;Jonathan Carlson;Jonathan Carlson;Hendrik Streeck

  • HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

    Zabrina L. Brumme;Zabrina L. Brumme;Mina John;Jonathan M. Carlson;Chanson J. Brumme

  • A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control

    István Bartha;Jonathan M Carlson;Chanson J Brumme;Paul J McLaren;Paul J McLaren;Paul J McLaren

  • Definition of the viral targets of protective HIV-1-specific T cell responses.

    Beatriz Mothe;Anuska Llano;F. Javier Ibarrondo;Marcus Daniels

  • Human Immunodeficiency Virus Type 1 Protease Cleavage Site Mutations Associated with Protease Inhibitor Cross-Resistance Selected by Indinavir, Ritonavir, and/or Saquinavir

    Hélène C. F. Côté;Zabrina L. Brumme;P. Richard Harrigan

  • Reduced Magnitude and Durability of Humoral Immune Responses to COVID-19 mRNA Vaccines Among Older Adults

    Unknown

  • Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.

    Jonathan M. Carlson;Jonathan M. Carlson;Zabrina L. Brumme;Christine M. Rousseau;Chanson J. Brumme

  • Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection

    Mark A. Brockman;Mark A. Brockman;Mark A. Brockman;Zabrina L. Brumme;Zabrina L. Brumme;Zabrina L. Brumme;Chanson J. Brumme;Chanson J. Brumme;Toshiyuki Miura;Toshiyuki Miura

  • HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1

    Toshiyuki Miura;Mark A. Brockman;Zabrina L. Brumme;Chanson J. Brumme

Frequent Co-Authors

Bruce D. Walker
Bruce D. Walker Harvard University
Mark A. Brockman
Mark A. Brockman Simon Fraser University
Chanson J. Brumme
Chanson J. Brumme University of British Columbia
Jonathan M. Carlson
Jonathan M. Carlson Microsoft (United States)
P. Richard Harrigan
P. Richard Harrigan University of British Columbia
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Simon Mallal
Simon Mallal Vanderbilt University Medical Center
Mina John
Mina John Royal Perth Hospital
Julio S. G. Montaner
Julio S. G. Montaner University of British Columbia
Thumbi Ndung'u
Thumbi Ndung'u University of KwaZulu-Natal

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