World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
100
Citations
31976
World Ranking
733
National Ranking
416

Medicine

D-Index
102
Citations
32356
World Ranking
7752
National Ranking
4038

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Immune system

Virology, Immunology, Epitope, Virus and Human leukocyte antigen are his primary areas of study. His Virology study incorporates themes from Cytotoxic T cell, CTL* and Immune system. Viral replication, Viremia, Lentivirus, T cell and Viral disease are the subjects of his Immunology studies.

His Epitope study combines topics in areas such as Chronic infection and CD8. Todd M. Allen combines subjects such as Viral evolution, Hepatitis C and Cellular immunity with his study of Virus. His Human leukocyte antigen research includes elements of Mutation, Acquired immunodeficiency syndrome and Allele.

His most cited work include:

  • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation (910 citations)
  • HIV evolution: CTL escape mutation and reversion after transmission. (788 citations)
  • Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. (718 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Virology, Immunology, Cytotoxic T cell, Epitope and Virus. His biological study spans a wide range of topics, including CTL*, Immune system, CD8 and Human leukocyte antigen. His Human leukocyte antigen research integrates issues from Mutation, Viral evolution and Allele.

His Immunology study focuses mostly on Viral load, Viremia, T cell, Simian immunodeficiency virus and Antigen. His Epitope research is included under the broader classification of Genetics. His study on Virus is mostly dedicated to connecting different topics, such as Hepatitis C.

He most often published in these fields:

  • Virology (55.75%)
  • Immunology (42.18%)
  • Cytotoxic T cell (23.89%)

What were the highlights of his more recent work (between 2013-2021)?

  • Virology (55.75%)
  • Immunology (42.18%)
  • Cytotoxic T cell (23.89%)

In recent papers he was focusing on the following fields of study:

Todd M. Allen spends much of his time researching Virology, Immunology, Cytotoxic T cell, CD8 and T cell. His Virology study integrates concerns from other disciplines, such as Epitope, Antibody and Human leukocyte antigen. Todd M. Allen works mostly in the field of Antibody, limiting it down to concerns involving Simian immunodeficiency virus and, occasionally, Viral replication.

His research integrates issues of Receptor, CTL* and T-cell receptor in his study of Human leukocyte antigen. His research brings together the fields of Viral evolution and Immunology. The concepts of his Cytotoxic T cell study are interwoven with issues in Major histocompatibility complex and Antigen.

Between 2013 and 2021, his most popular works were:

  • The epigenetic landscape of T cell exhaustion (389 citations)
  • Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9 (348 citations)
  • Selection bias at the heterosexual HIV-1 transmission bottleneck (179 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Immune system

Todd M. Allen focuses on Immunology, Virology, T cell, Human leukocyte antigen and CD8. His Acquired immune system, Inflammation, Viral replication and CTL* study in the realm of Immunology connects with subjects such as In patient. His Virology research incorporates themes from Immune system and Mucosal Infection.

His T cell research is multidisciplinary, relying on both Hematopoietic stem cell transplantation, HIV vaccine, Conserved sequence, Epitope and Immunogen. The study incorporates disciplines such as Immunogenicity, Receptor, Cellular immunity and T-cell receptor in addition to Human leukocyte antigen. His studies deal with areas such as Chromatin, Enhancer, Cytotoxic T cell, Regulation of gene expression and Epigenetics as well as CD8.

Best Publications

  • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

    Pereyra F;Jia X;McLaren Pj

  • HIV evolution: CTL escape mutation and reversion after transmission.

    A J Leslie;K J Pfafferott;P Chetty;R Draenert

  • Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

    Photini Kiepiela;Alasdair J. Leslie;Isobella Honeyborne;Danni Ramduth

  • The epigenetic landscape of T cell exhaustion

    Debattama R. Sen;James Kaminski;R. Anthony Barnitz;Makoto Kurachi

  • Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia.

    Todd M. Allen;David H. O'Connor;Peicheng Jing;John L. Dzuris

  • Differential natural killer cell–mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes

    Galit Alter;Maureen P. Martin;Nickolas Teigen;William H Carr

  • Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

    Pankaj Kumar Mandal;Pankaj Kumar Mandal;Leonardo Manuel Ramos Ferreira;Ryan Collins;Torsten B Meissner

  • Adaptation of HIV-1 to human leukocyte antigen class I

    Y. Kawashima;K. Pfafferott;J. Frater;P. Matthews

  • Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.

    David T. Evans;David T. Evans;David H. O'Connor;Peicheng Jing;John L. Dzuris

  • Effective Induction of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Macaques by Using a Multiepitope Gene and DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccination Regimen

    Tomas Hanke;Rachel V. Samuel;Tom J. Blanchard;Veronica C. Neumann

  • Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.

    Marcus Altfeld;Marylyn M. Addo;Eric S. Rosenberg;Frederick M. Hecht

  • Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection.

    David H. O'Connor;Todd M. Allen;Thorsten U. Vogel;Peicheng Jing

  • NATURALLY OCCURRING DOMINANT RESISTANCE MUTATIONS TO HEPATITIS C VIRUS PROTEASE AND POLYMERASE INHIBITORS IN TREATMENT-NAIVE PATIENTS

    Thomas Kuntzen;Joerg Timm;Andrew Berical;Niall Lennon

  • HIV-1 superinfection despite broad CD8 + T-cell responses containing replication of the primary virus

    Marcus Altfeld;Todd M. Allen;Xu G. Yu;Mary N. Johnston

  • HIV-1 adaptation to NK-cell-mediated immune pressure

    Galit Alter;David Heckerman;Arne Schneidewind;Lena Fadda

  • Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex.

    Marcelo J. Kuroda;Jörn E. Schmitz;Dan H. Barouch;Abie Craiu

  • Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

    Rachel H. McMahan;Lucy Golden-Mason;Michael I. Nishimura;Brian J. McMahon

  • Whole genome deep sequencing of HIV-1 reveals the impact of early minor variants upon immune recognition during acute infection

    Matthew R. Henn;Christian L. Boutwell;Patrick Charlebois;Niall J Lennon

  • HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1

    Marcus Altfeld;Elizabeth T Kalife;Ying Qi;Hendrik Streeck

  • Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.

    Arne Schneidewind;Mark A. Brockman;Mark A. Brockman;Ruifeng Yang;Rahma I. Adam

Frequent Co-Authors

Bruce D. Walker
Bruce D. Walker Harvard University
Marcus Altfeld
Marcus Altfeld University Medical Center Hamburg-Eppendorf
Georg M. Lauer
Georg M. Lauer Harvard University
David I. Watkins
David I. Watkins George Washington University
Eric S. Rosenberg
Eric S. Rosenberg Harvard University
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Arthur Y. Kim
Arthur Y. Kim Harvard University
Christian Brander
Christian Brander University of Vic - Central University of Catalonia
Zabrina L. Brumme
Zabrina L. Brumme Simon Fraser University
Raymond T. Chung
Raymond T. Chung Harvard University

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Related Online Degrees & Career Pathways

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