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Immunology

D-Index
61
Citations
18352
World Ranking
3197
National Ranking
1498

Overview

Georg M. Lauer is affiliated with Harvard University in the United States, specializing in research within the field of Medicine. Their work spans several subfields including Epidemiology, Hepatology, Immunology, Molecular Biology, and Cancer Research. The scientist's research primarily addresses topics related to liver diseases, immune cell function, and viral hepatitis.

Lauer's notable research topics include:

  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Liver Diseases and Immunity
  • Single-cell and spatial transcriptomics

Their publication record includes several recent papers covering aspects of immune response, liver disease, and chronic infection. Key recent papers are:

  • Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans, 2021, Nature Immunology
  • Differentiation of exhausted CD8+ T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory, 2021, Nature Immunology
  • Aspirin for Metabolic Dysfunction-Associated Steatotic Liver Disease Without Cirrhosis, 2024, JAMA
  • Distinct Hepatic Gene-Expression Patterns of NAFLD in Patients With Obesity, 2021, Hepatology Communications
  • A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection, 2024, Nature

Lauer frequently collaborates with other scientists, with prominent co-authors including Raymond T. Chung, Arthur Y. Kim, Adam J. Gehring, Nir Hacohen, and Nadia Alatrakchi. These collaborations indicate a broad network within hepatology and immunology research communities.

Publications by Lauer appear frequently in specialized journals such as:

  • Journal of Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Infectious Diseases
  • Hepatology
  • Clinical Infectious Diseases

This publication history suggests a focus on infectious diseases affecting liver function, as well as immune mechanisms underlying chronic viral infections and liver pathology.

Best Publications

  • Hepatitis C Virus Infection

    Georg M. Lauer;Bruce D. Walker

  • Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

    Michael A. Paley;Daniela C. Kroy;Pamela M. Odorizzi;Jonathan B. Johnnidis

  • The epigenetic landscape of T cell exhaustion

    Debattama R. Sen;James Kaminski;R. Anthony Barnitz;Makoto Kurachi

  • Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

    Norbert H. Gruener;Franziska Lechner;Maria-Christina Jung;Helmut Diepolder

  • The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C virus infection

    Jason Grebely;Kimberly A Page;Rachel Sacks-Davis;Martin Schim van der Loeff

  • NATURALLY OCCURRING DOMINANT RESISTANCE MUTATIONS TO HEPATITIS C VIRUS PROTEASE AND POLYMERASE INHIBITORS IN TREATMENT-NAIVE PATIENTS

    Thomas Kuntzen;Joerg Timm;Andrew Berical;Niall Lennon

  • CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

    Prakash K. Gupta;Prakash K. Gupta;Jernej Godec;Jernej Godec;David Wolski;Emily Adland

  • High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection

    Georg M. Lauer;Eleanor Barnes;Eleanor Barnes;Michaela Lucas;Joerg Timm

  • CD8 Epitope Escape and Reversion in Acute HCV Infection

    Joerg Timm;Georg M. Lauer;Daniel G. Kavanagh;Isabelle Sheridan

  • Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

    Cheryl L. Day;Nilufer P. Seth;Michaela Lucas;Heiner Appel

  • Broad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection

    Cheryl L. Day;Georg M. Lauer;Gregory K. Robbins;Barbara McGovern;Barbara McGovern

  • Comprehensive analyses of CD8+ T cell responses during longitudinal study of acute human hepatitis C.

    Andrea L. Cox;Timothy Mosbruger;Georg M. Lauer;Drew Pardoll

  • Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8 + T cells

    Lucy J. Walker;Yu-Hoi Kang;Matthew O. Smith;Hannah Tharmalingham

  • Hepatitis C virus clearance, reinfection, and persistence, with insights from studies of injecting drug users: towards a vaccine

    Jason Grebely;Maria Prins;Margaret Hellard;Andrea L Cox

  • Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence

    Julian Schulze zur Wiesch;Julian Schulze zur Wiesch;Donatella Ciuffreda;Lia Lewis-Ximenez;Victoria Olivia Kasprowicz

  • Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts

    Priya Duggal;Chloe L. Thio;Genevieve L. Wojcik;James J. Goedert

  • Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities.

    Georg M. Lauer;Kei Ouchi;Raymond T. Chung;Tam N. Nguyen

  • High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome

    Victoria Kasprowicz;Julian Schulze zur Wiesch;Julian Schulze zur Wiesch;Julian Schulze zur Wiesch;Thomas Kuntzen;Brian E. Nolan

  • Broad Repertoire of the CD4+ Th Cell Response in Spontaneously Controlled Hepatitis C Virus Infection Includes Dominant and Highly Promiscuous Epitopes

    Julian Schulze zur Wiesch;Georg M. Lauer;Cheryl L. Day;Arthur Y. Kim

  • Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans.

    Kathleen B. Yates;Kathleen B. Yates;Pierre Tonnerre;Pierre Tonnerre;Genevieve E. Martin;Genevieve E. Martin;Ulrike Gerdemann

  • CTL epitope escape and reversion in acute HCV infection.

    J Timm;G Lauer;D Kavanagh;A Kim

Frequent Co-Authors

Arthur Y. Kim
Arthur Y. Kim Harvard University
Raymond T. Chung
Raymond T. Chung Harvard University
Bruce D. Walker
Bruce D. Walker Harvard University
Todd M. Allen
Todd M. Allen Harvard University
Paul Klenerman
Paul Klenerman University of Oxford
Andrea L. Cox
Andrea L. Cox Johns Hopkins University School of Medicine
Andrew R. Lloyd
Andrew R. Lloyd University of New South Wales
Margaret Hellard
Margaret Hellard Burnet Institute
Jason Grebely
Jason Grebely University of New South Wales
Gregory J. Dore
Gregory J. Dore University of New South Wales

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