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Christoph Neumann-Haefelin

Christoph Neumann-Haefelin

D-Index & Metrics

Microbiology

D-Index
47
Citations
8868
World Ranking
4776
National Ranking
329

Overview

Christoph Neumann-Haefelin is affiliated with the University of Freiburg in Germany and has a primary focus on medical research.

Their main field of study is Medicine, with a significant emphasis on subfields including Hepatology, Epidemiology, Immunology, Infectious Diseases, and Oncology.

The key topics addressed in their research include:

  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Liver Disease Diagnosis and Treatment
  • Hepatitis Viruses Studies and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • COVID-19 Clinical Research Studies

The scientist has contributed frequently to several publication venues:

  • Journal of Hepatology
  • Zeitschrift für Gastroenterologie
  • Gut
  • Nature Communications
  • JHEP Reports

Notable recent papers authored or co-authored by Christoph Neumann-Haefelin include:

  • "Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine," 2021, Nature
  • "Characterization of pre-existing and induced SARS-CoV-2-specific CD8+ T cells," 2020, Nature Medicine
  • "Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions," 2021, Immunity
  • "Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease," 2021, Gut
  • "Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants," 2021, Nature Communications

Their frequent collaborators are:

  • Robert Thimme
  • Maike Hofmann
  • Bertram Bengsch
  • Tobias Boettler
  • Hendrik Luxenburger

Best Publications

  • T Cells with a CD4+CD25+ Regulatory Phenotype Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Chronic Hepatitis C Virus Infection

    Tobias Boettler;Hans Christian Spangenberg;Christoph Neumann-Haefelin;Elisabeth Panther

  • Rapid and stable mobilization of CD8 + T cells by SARS-CoV-2 mRNA vaccine.

    Valerie Oberhardt;Hendrik Luxenburger;Janine Kemming;Isabel Schulien

  • Immunodominance and functional alterations of tumor‐associated antigen‐specific CD8+ T‐cell responses in hepatocellular carcinoma

    Tobias Flecken;Nathalie Schmidt;Sandra Hild;Emma Gostick

  • Characterization of pre-existing and induced SARS-CoV-2-specific CD8 + T cells.

    Isabel Schulien;Janine Kemming;Valerie Oberhardt;Katharina Wild

  • Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions.

    Marius Schwabenland;Henrike Salié;Jovan Tanevski;Saskia Killmer

  • Restoration of HCV-specific CD8+ T cell function by interferon-free therapy

    Bianca Martin;Nadine Hennecke;Volker Lohmann;Antonin Kayser

  • Dominant influence of an HLA‐B27 restricted CD8+ T cell response in mediating HCV clearance and evolution

    Christoph Neumann-Haefelin;Susan McKiernan;Scott Ward;Sergei Viazov

  • TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation.

    Dominik Wieland;Janine Kemming;Anita Schuch;Florian Emmerich

  • T cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma.

    Unknown

  • Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection†

    Hans Christian Spangenberg;Sergei Viazov;Nadine Kersting;Christoph Neumann-Haefelin

  • In vitro studies with purified components reveal signal recognition particle (SRP) and SecA/SecB as constituents of two independent protein-targeting pathways of Escherichia coli.

    Hans-Georg Koch;Thomas Hengelage;Christoph Neumann-Haefelin;Juan MacFarlane

  • Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease.

    Stephan Urban;Christoph Neumann-Haefelin;Pietro Lampertico

  • Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants.

    Sebastian Weigang;Jonas Fuchs;Gert Zimmer;Daniel Schnepf

  • SRP-dependent co-translational targeting and SecA-dependent translocation analyzed as individual steps in the export of a bacterial protein.

    Christoph Neumann‐Haefelin;Ute Schäfer;Matthias Müller;Hans‐Georg Koch

  • SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis

    Unknown

  • Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load.

    Anita Schuch;Elahe Salimi Alizei;Kathrin Heim;Dominik Wieland

  • Virological and immunological determinants of intrahepatic virus‐specific CD8+ T‐cell failure in chronic hepatitis C virus infection

    Christoph Neumann-Haefelin;Jörg Timm;Hans Christian Spangenberg;Natalie Wischniowski

  • Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.

    Eva Dazert;Christoph Neumann-Haefelin;Stéphane Bressanelli;Karen Fitzmaurice

  • Patterns of Resistance-Associated Substitutions in Patients With Chronic HCV Infection Following Treatment With Direct-Acting Antivirals

    Julia Dietz;Simone Susser;Johannes Vermehren;Kai-Henrik Peiffer

  • T cell response in hepatitis C virus infection.

    C. Neumann-Haefelin;H.E. Blum;F.V. Chisari;R. Thimme

  • Analysis of CD127 and KLRG1 expression on hepatitis C virus-specific CD8+ T cells reveals the existence of different memory T-cell subsets in the peripheral blood and liver.

    Bertram Bengsch;Hans Christian Spangenberg;Nadine Kersting;Christoph Neumann-Haefelin

  • Uptake and presentation of hepatitis C virus–like particles by human dendritic cells

    Heidi Barth;Axel Ulsenheimer;Gerd R. Pape;Helmut M. Diepolder

  • Deep spatial profiling of human COVID-19 brains

    Marius Schwabenland;Henrike Salié;Jovan Tanevski;Saskia Killmer

Frequent Co-Authors

Robert Thimme
Robert Thimme University of Freiburg
Hubert E. Blum
Hubert E. Blum University of Freiburg
David Price
David Price University of Aberdeen
Michael Roggendorf
Michael Roggendorf Technical University of Munich
Emma Gostick
Emma Gostick Cardiff University
Ralf Bartenschlager
Ralf Bartenschlager Heidelberg University
Paul Klenerman
Paul Klenerman University of Oxford
Thomas F. Baumert
Thomas F. Baumert University of Strasbourg
Volker Lohmann
Volker Lohmann Heidelberg University
Christoph Sarrazin
Christoph Sarrazin Goethe University Frankfurt

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