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Overview

Christoph Sarrazin is affiliated with Goethe University Frankfurt in Germany and has a significant research output in the field of medicine, with a particular emphasis on hepatology. Their body of work spans a range of related subfields including epidemiology, infectious diseases, rheumatology, and cardiology and cardiovascular medicine.

Their research predominantly focuses on liver-related conditions and viral hepatitis. This is reflected in their main topics of study which include:

  • Hepatitis C virus research
  • Liver disease diagnosis and treatment
  • Hepatitis B virus studies
  • Liver disease and transplantation
  • HIV/AIDS drug development and treatment
  • Systemic lupus erythematosus research
  • Hepatitis viruses studies and epidemiology

Christoph Sarrazin has contributed extensively to scientific literature with several recent papers published in renowned journals. Notable publications include:

  • "Granulocyte-colony stimulating factor (G-CSF) to treat acute-on-chronic liver failure: A multicenter randomized trial (GRAFT study)", 2021, Journal of Hepatology
  • "JNJ-56136379, an HBV Capsid Assembly Modulator, Is Well-Tolerated and Has Antiviral Activity in a Phase 1 Study of Patients With Chronic Infection", 2020, Gastroenterology
  • "Treatment failure with DAA therapy: Importance of resistance", 2021, Journal of Hepatology
  • "Hepatitis D double reflex testing of all hepatitis B carriers in low-HBV- and high-HBV/HDV-prevalence countries", 2023, Journal of Hepatology
  • "Failure on voxilaprevir, velpatasvir, sofosbuvir and efficacy of rescue therapy", 2020, Journal of Hepatology

Their collaborations include frequent co-authors such as Stefan Zeuzem, Julia Dietz, Christiana Graf, Thomas Berg, and Peter Buggisch, indicating a consistent engagement with experts in related fields.

Christoph Sarrazin's research has been published most often in these venues:

  • Journal of Hepatology
  • Zeitschrift für Gastroenterologie
  • JHEP Reports
  • Journal of Viral Hepatitis
  • Liver International

Their work on liver-related diseases, viral hepatitis, and antiviral therapies contribute to ongoing efforts in medical research into diagnosis, treatment, and epidemiology of these conditions.

Best Publications

  • EASL Recommendations on Treatment of Hepatitis C

    Jean-Michel Pawlotsky;Alessio Aghemo;Geoffrey Dusheiko;Xavier Forns

  • Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study

    Sarah Blach;Stefan Zeuzem;Michael Manns;Ibrahim Altraif

  • Performance of Transient Elastography for the Staging of Liver Fibrosis: A Meta-Analysis

    Mireen Friedrich-Rust;Mei-Fang Ong;Swantje Martens;Christoph Sarrazin

  • Global prevalence, treatment, and prevention of hepatitis B virus infection in 2016: a modelling study

    Devin Razavi-Shearer;Ivane Gamkrelidze;Mindie H Nguyen;Ding-Shinn Chen

  • Liver Fibrosis in Viral Hepatitis: Noninvasive Assessment with Acoustic Radiation Force Impulse Imaging versus Transient Elastography

    Mireen Friedrich-Rust;Katrin Wunder;Susanne Kriener;Fariba Sotoudeh

  • Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir.

    Christoph Sarrazin;Tara L. Kieffer;Doug Bartels;Brian Hanzelka

  • Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin.

    Thomas Berg;Michael von Wagner;Samer Nasser;Christoph Sarrazin

  • Resistance to Direct Antiviral Agents in Patients With Hepatitis C Virus Infection

    Christoph Sarrazin;Stefan Zeuzem

  • Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3

    Stefan Zeuzem;Rolf Hultcrantz;Marc Bourliere;Tobias Goeser

  • A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

    Stephan Buch;Felix Stickel;Eric Trépo;Michael Way

  • The importance of resistance to direct antiviral drugs in HCV infection in clinical practice.

    Christoph Sarrazin

  • Real-time elastography for noninvasive assessment of liver fibrosis in chronic viral hepatitis.

    Mireen Friedrich-Rust;Mei-Fang Ong;Eva Herrmann;Volker Dries

  • Telaprevir and pegylated interferon-alpha-2a inhibit wild-type and resistant genotype 1 hepatitis C virus replication in patients.

    Tara L. Kieffer;Christoph Sarrazin;Janice S. Miller;Martin W. Welker

  • Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis

    Tobias J. Weismüller;Tobias J. Weismüller;Palak J. Trivedi;Annika Bergquist;Mohamad Imam;Mohamad Imam

  • Effects of fractionated plasma separation and adsorption on survival in patients with acute-on-chronic liver failure

    Andreas Kribben;Guido Gerken;Sebastian Haag;Stefan Herget–Rosenthal

  • Treatment predictors of a sustained virologic response in hepatitis B and C

    Annika Kau;Johannes Vermehren;Christoph Sarrazin

  • Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues†

    Florian van Bömmel;Robert A. de Man;Heiner Wedemeyer;Katja Deterding

  • SCH 503034, a Novel Hepatitis C Virus Protease Inhibitor, Plus Pegylated Interferon α-2b for Genotype 1 Nonresponders

    Christoph Sarrazin;Christoph Sarrazin;Regine Rouzier;Frank Wagner;Nicole Forestier;Nicole Forestier

  • Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy.

    Florian van Bömmel;Bernhard Zöllner;Christoph Sarrazin;Ulrich Spengler

  • Peginterferon alfa-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients

    Stefan Zeuzem;Rolf Hultcrantz;Marc Bourliere;Tobias Goeser

Frequent Co-Authors

Stefan Zeuzem
Stefan Zeuzem Goethe University Frankfurt
Eva Herrmann
Eva Herrmann Goethe University Frankfurt
Heiner Wedemeyer
Heiner Wedemeyer Hannover Medical School
Michael P. Manns
Michael P. Manns Hannover Medical School
Stefan Mauss
Stefan Mauss Université Paris Cité
Markus Cornberg
Markus Cornberg Hannover Medical School
Ulrich Spengler
Ulrich Spengler University of Bonn
Maria Buti
Maria Buti Instituto de Salud Carlos III
Christophe Moreno
Christophe Moreno Université Libre de Bruxelles

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