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Ulrich Spengler

Ulrich Spengler

D-Index & Metrics

Immunology

D-Index
94
Citations
30114
World Ranking
934
National Ranking
57

Medicine

D-Index
95
Citations
30705
World Ranking
10127
National Ranking
558

Overview

Ulrich Spengler is affiliated with the University of Bonn in Germany. Their work primarily focuses on Medicine, with a significant emphasis on Hepatology. The scientist's research portfolio includes contributions to several subfields, such as Hepatology, Epidemiology, Immunology, Surgery, and Genetics.

The researcher's main topics of study address various aspects of liver-related diseases and immune system interactions. Key topics include Liver Disease Diagnosis and Treatment, Liver Diseases and Immunity, Hepatitis C virus research, Hepatitis B Virus Studies, Liver Disease and Transplantation, Immune Cell Function and Interaction, and HIV Research and Treatment.

Ulrich Spengler has published in multiple notable venues, often contributing to journals focused on liver diseases and related biomedical fields. Frequent publication venues include:

  • Journal of Hepatology
  • Zeitschrift für Gastroenterologie
  • Gastroenterology
  • Frontiers in Medicine
  • The Journal of Infectious Diseases

Some of the recent papers associated with Ulrich Spengler's domain include:

  • A placebo-controlled randomised trial of budesonide for PBC following an insufficient response to UDCA (2020, Journal of Hepatology)
  • Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1 (2020, Gastroenterology)
  • Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization (2022, Immunity)
  • Single-cell RNA sequencing identifies a population of human liver-type ILC1s (2023, Cell Reports)
  • Liver Fibrosis-From Mechanisms of Injury to Modulation of Disease (2022, Frontiers in Medicine)

Ulrich Spengler has collaborated frequently with several co-authors, indicating ongoing scientific partnerships. Notable frequent co-authors include:

  • Christian P. Strassburg
  • Philipp Lutz
  • Bettina Langhans
  • Jacob Nattermann
  • Leona Dold

Best Publications

  • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

    Vijayaprakash Suppiah;Max Moldovan;Golo Ahlenstiel;Thomas Berg

  • Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

    Vlad Ratziu;Vlad Ratziu;Stephen A. Harrison;Sven Francque;Pierre Bedossa

  • Polymorphic structure of the tumor necrosis factor (TNF) locus: an NcoI polymorphism in the first intron of the human TNF-beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF-beta production.

    Gerald Messer;Ulrich Spengler;Maria C. Jung;G. Honold

  • Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-alfa-2a plus ribavirin.

    Thomas Berg;Michael von Wagner;Samer Nasser;Christoph Sarrazin

  • Effect of antiretroviral therapy on liver-related mortality in patients with HIV and hepatitis C virus coinfection.

    Naztfa Qurishi;Christina Kreuzberg;Guido Lüchters;Wolfgang Effenberger

  • Long term outcome after transjugular intrahepatic portosystemic stent-shunt in non-transplant cirrhotics with hepatorenal syndrome: a phase II study

    K A Brensing;J Textor;J Perz;P Schiedermaier

  • Ursodeoxycholic acid for treatment of primary sclerosing cholangitis: A placebo‐controlled trial

    Ulrich Beuers;Ulrich Spengler;Wolfgang Kruis;ülker Aydemir

  • Budesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitis

    Michael P. Manns;Marek Woynarowski;Wolfgang Kreisel;Yoav Lurie

  • NATURALLY OCCURRING DOMINANT RESISTANCE MUTATIONS TO HEPATITIS C VIRUS PROTEASE AND POLYMERASE INHIBITORS IN TREATMENT-NAIVE PATIENTS

    Thomas Kuntzen;Joerg Timm;Andrew Berical;Niall Lennon

  • A Polymorphism Near IL28B Is Associated With Spontaneous Clearance of Acute Hepatitis C Virus and Jaundice

    Hans L. Tillmann;Alex J. Thompson;Keyur Patel;Manfred Wiese

  • Long-term efficacy of tenofovir monotherapy for hepatitis B virus-monoinfected patients after failure of nucleoside/nucleotide analogues†

    Florian van Bömmel;Robert A. de Man;Heiner Wedemeyer;Katja Deterding

  • Tenofovir for patients with lamivudine-resistant hepatitis B virus (HBV) infection and high HBV DNA level during adefovir therapy.

    Florian van Bömmel;Bernhard Zöllner;Christoph Sarrazin;Ulrich Spengler

  • Safety and efficacy of lamivudine in patients with severe acute or fulminant hepatitis B, a multicenter experience

    H. L. Tillmann;J. Hadem;L. Leifeld;K. Zachou

  • Bleeding complications after percutaneous liver biopsy. An analysis of risk factors.

    Birgit Terjung;Isabelle Lemnitzer;Franz Ludwig Dumoulin;Wolfgang Effenberger

  • Surface expression and cytolytic function of natural killer cell receptors is altered in chronic hepatitis C

    Jacob Nattermann;Georg Feldmann;Golo Ahlenstiel;Bettina Langhans

  • norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis

    Peter Fickert;Gideon M Hirschfield;Gerald Denk;Hanns-Ulrich Marschall

  • Tumor necrosis factor α in the pathogenesis of human and murine fulminant hepatic failure

    Konrad Streetz;Ludger Leifeld;Danja Grundmann;Jan Ramakers

  • Association between the PNPLA3 (rs738409 C>G) variant and hepatocellular carcinoma: Evidence from a meta‐analysis of individual participant data

    Eric Trepo;Pierre Nahon;Pierre Nahon;Gianluca Bontempi;Luca Valenti

  • HIV and hepatitis C virus co-infection

    Jürgen Kurt Rockstroh;Ulrich Spengler

  • Hepatitis B virus antigen-specific T-cell activation in patients with acute and chronic hepatitis B

    M.-C. Jung;U. Spengler;W. Schraut;R. Hoffmann

  • Daclatasvir plus sofosbuvir, with or without ribavirin, achieved high sustained virological response rates in patients with HCV infection and advanced liver disease in a real-world cohort

    Tania Mara Welzel;Jörg Petersen;Kerstin Herzer;Peter Ferenci

Frequent Co-Authors

Tilman Sauerbruch
Tilman Sauerbruch University of Bonn
Jacob Nattermann
Jacob Nattermann University Hospital Bonn
Christian P. Strassburg
Christian P. Strassburg University Hospital Bonn
Jürgen K. Rockstroh
Jürgen K. Rockstroh University Hospital Bonn
Jonel Trebicka
Jonel Trebicka University Hospital of Münster
Johannes Oldenburg
Johannes Oldenburg University of Bonn
Stefan Zeuzem
Stefan Zeuzem Goethe University Frankfurt
Gerd R. Pape
Gerd R. Pape Ludwig-Maximilians-Universität München
Frank Lammert
Frank Lammert Saarland University
Stefan Mauss
Stefan Mauss Université Paris Cité

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