His scientific interests lie mostly in Immunology, Cell biology, Cytokine, Transcription factor and Cellular differentiation. Mark H. Kaplan combines topics linked to Interleukin 12 with his work on Immunology. His Cell biology research is multidisciplinary, relying on both Stimulation, Interleukin 17, Cyclin-dependent kinase 2 and T-cell receptor.
His Cytokine study combines topics in areas such as Phenotype and Flow cytometry. His research investigates the connection between Transcription factor and topics such as Signal transduction that intersect with problems in Immunopathology, Inflammatory bowel disease and In vivo. In his work, STAT protein, STAT4, Response element and General transcription factor is strongly intertwined with STAT6, which is a subfield of Cellular differentiation.
Mark H. Kaplan mostly deals with Immunology, Cell biology, Cytokine, Transcription factor and Immune system. His work carried out in the field of Immunology brings together such families of science as Cytotoxic T cell and STAT4. His biological study spans a wide range of topics, including Phenotype, T cell, Regulation of gene expression and Cellular differentiation.
The various areas that he examines in his Transcription factor study include Molecular biology, Gene expression and Ectopic expression. He combines subjects such as Cancer research and STAT protein with his study of STAT6. Mark H. Kaplan has researched IL-2 receptor in several fields, including Interleukin 12, Interleukin 21 and Natural killer T cell.
Mark H. Kaplan spends much of his time researching Immunology, Cell biology, Transcription factor, Inflammation and Immune system. Mark H. Kaplan integrates several fields in his works, including Immunology and Population. His Cell biology research integrates issues from Regulation of gene expression, Gene expression, Gene, Cytokine and T cell.
His Transcription factor study combines topics from a wide range of disciplines, such as Cell, Signal transduction and Cellular differentiation. His Inflammation research includes elements of STAT6, Homeostasis, Adoptive cell transfer, Lung and FOXP3. His research integrates issues of Secretion and Allergic inflammation in his study of Immune system.
Mark H. Kaplan focuses on Immunology, Cell biology, Transcription factor, Immune system and Inflammation. Mark H. Kaplan undertakes multidisciplinary studies into Immunology and Population in his work. His studies in Cell biology integrate themes in fields like T cell, Regulation of gene expression, Gene expression and Cellular differentiation.
His research in Transcription factor intersects with topics in Retinoic acid, General transcription factor and Epidermis. The concepts of his Immune system study are interwoven with issues in Proinflammatory cytokine, Inflammatory bowel disease, Homeostasis, Crohn's disease and Effector. His Inflammation study integrates concerns from other disciplines, such as Tissue homeostasis and FOXP3.
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Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells
Mark H Kaplan;Ulrike Schindler;Stephen T Smiley;Michael J Grusby.
Immunity (1996)
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
Mark H. Kaplan;Ya-Lin Sun;Timothy Hoey;Michael J. Grusby.
Nature (1996)
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation
Hua Chen Chang;Sarita Sehra;Ritobrata Goswami;Weiguo Yao.
Nature Immunology (2010)
Stat3 and Stat4 Direct Development of IL-17-Secreting Th Cells
Anubhav N. Mathur;Hua Chen Chang;Dimitrios G. Zisoulis;Gretta L. Stritesky.
Journal of Immunology (2007)
IL- 6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3⁺ regulatory T cells
Thomas Korn;Meike Mitsdoerffer;Andrew L. Croxford;Amit Awasthi.
Proceedings of the National Academy of Sciences of the United States of America (2008)
Immunoglobulin E Production in the Absence of Interleukin-4-Secreting CD1-Dependent Cells
Stephen T. Smiley;Mark H. Kaplan;Michael J. Grusby.
Science (1997)
IL-23 Promotes Maintenance but Not Commitment to the Th17 Lineage
Gretta L. Stritesky;Norman Yeh;Mark H. Kaplan.
Journal of Immunology (2008)
A Brief History of IL-9
Ritobrata Goswami;Mark H. Kaplan.
Journal of Immunology (2011)
The development and in vivo function of T helper 9 cells
Mark H. Kaplan;Matthew M. Hufford;Matthew R. Olson.
Nature Reviews Immunology (2015)
Th9 cells: differentiation and disease.
Mark H. Kaplan.
Immunological Reviews (2013)
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