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Biology and Biochemistry

D-Index
70
Citations
28782
World Ranking
6857
National Ranking
3163

Overview

Yuka Kanno is a researcher affiliated with the National Institutes of Health in the United States. Their work spans multiple areas within immunology and microbiology, with a primary focus on immunology. They have contributed to 42 publications in this field, as well as 17 publications related to medicine.

Their research subfields include immunology, oncology, epidemiology, pathology and forensic medicine, and surgery. Within the scope of their scientific inquiries, their main topics of work cover immune cell function and interaction, T-cell and B-cell immunology, IL-33, ST2, and ILC pathways, cytokine signaling pathways and interactions, interferon and immune responses, Mycobacterium research and diagnosis, and immunotherapy and immune responses.

Kanno has published in a range of scientific venues. The most frequent publication venues include:

  • Science Immunology (4 publications)
  • Cell (3 publications)
  • Immunity (3 publications)
  • The Journal of Immunology (3 publications)
  • Nature Immunology (2 publications)

Collaborations have been established with several frequent coauthors, including:

  • John J. O'Shea (17 collaborations)
  • Hiroyuki Nagashima (11 collaborations)
  • Chen Yao (7 collaborations)
  • Hong-Wei Sun (7 collaborations)
  • Stephen R. Brooks (7 collaborations)

Among Kanno's recent scholarly papers, notable titles are:

  • The JAK-STAT pathway at 30: Much learned, much more to do (2022, Cell)
  • SnapShot: Jak-STAT Signaling II (2020, Cell)
  • Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells (2020, Immunity)
  • MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23 (2021, Immunity)
  • A central role for STAT5 in the transcriptional programing of T helper cell metabolism (2022, Science Immunology)

Best Publications

  • Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation

    Arian Laurence;Cristina M. Tato;Todd S. Davidson;Yuka Kanno

  • Generation of pathogenic T H 17 cells in the absence of TGF-β signalling

    Kamran Ghoreschi;Arian Laurence;Xiang-Ping Yang;Cristina M Tato

  • Impaired T H 17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

    Joshua D. Milner;Jason M. Brenchley;Jason M. Brenchley;Arian Laurence;Alexandra F. Freeman

  • Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

    Gang Wei;Lai Wei;Jinfang Zhu;Chongzhi Zang

  • JAK inhibition as a therapeutic strategy for immune and inflammatory diseases.

    Daniella M Schwartz;Yuka Kanno;Alejandro Villarino;Michael Ward

  • Mechanisms and consequences of Jak–STAT signaling in the immune system

    Alejandro V Villarino;Yuka Kanno;John J O'Shea

  • Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

    Hiroaki Takatori;Yuka Kanno;Wendy T. Watford;Cristina M. Tato

  • Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.

    Zhi Chen;Arian Laurence;Yuka Kanno;Margit Pacher-Zavisin

  • Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

    Lydia Durant;Wendy T. Watford;Haydeé L. Ramos;Arian Laurence

  • Signaling by IL‐12 and IL‐23 and the immunoregulatory roles of STAT4

    Wendy T. Watford;Bruce D. Hissong;Jay H. Bream;Yuka Kanno

  • Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene.

    Thomas Holtschke;Jürgen Löhler;Yuka Kanno;Thomas Fehr

  • Nonredundant roles for Stat5a/b in directly regulating Foxp3

    Zhengju Yao;Zhengju Yao;Yuka Kanno;Marc Kerenyi;Geoffrey Stephens

  • Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5.

    Xiang Ping Yang;Kamran Ghoreschi;Scott M. Steward-Tharp;Jaime Rodriguez-Canales

  • Mechanisms of Jak/STAT Signaling in Immunity and Disease

    Alejandro V. Villarino;Yuka Kanno;John R. Ferdinand;John J. O’Shea

  • Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway

    Kevin M. Elias;Kevin M. Elias;Arian Laurence;Todd S. Davidson;Geoffrey Stephens

  • T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

    Takashi Usui;Jan C. Preiss;Yuka Kanno;Zheng Ju Yao

  • Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition

    Shingo Nakayamada;Yuka Kanno;Hayato Takahashi;Dragana Jankovic

  • BACH2 represses effector programs to stabilize T reg -mediated immune homeostasis

    Rahul Roychoudhuri;Kiyoshi Hirahara;Kiyoshi Hirahara;Kambiz Mousavi;David Clever

  • Selective recognition of acetylated histones by bromodomain proteins visualized in living cells.

    Tomohiko Kanno;Tomohiko Kanno;Yuka Kanno;Richard M Siegel;Moon Kyoo Jang

  • Helper T cell diversity and plasticity.

    Shingo Nakayamada;Hayato Takahashi;Yuka Kanno;John J O'Shea

Frequent Co-Authors

John J. O'Shea
John J. O'Shea National Institutes of Health
Arian Laurence
Arian Laurence University of Oxford
Kiyoshi Hirahara
Kiyoshi Hirahara Chiba University
Hong-Wei Sun
Hong-Wei Sun National Institutes of Health
Alejandro V. Villarino
Alejandro V. Villarino National Institutes of Health
Keiko Ozato
Keiko Ozato Eunice Kennedy Shriver National Institute of Child Health and Human Development
Kamran Ghoreschi
Kamran Ghoreschi Charité - University Medicine Berlin
Dragana Jankovic
Dragana Jankovic National Institute of Allergy and Infectious Diseases
Vittorio Sartorelli
Vittorio Sartorelli National Institutes of Health
Lothar Hennighausen
Lothar Hennighausen National Institutes of Health

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