His primary areas of investigation include Cell biology, Immunology, Cellular differentiation, Interleukin 3 and Interleukin 21. His Cell biology research is multidisciplinary, incorporating elements of Regulation of gene expression, STAT4, microRNA and Cell growth. In the field of Immunology, his study on Interleukin 10, Interleukin and PAPA syndrome overlaps with subjects such as Interleukin 1 receptor antagonist.
Arian Laurence interconnects Endothelial stem cell, STAT3 and Interleukin 17, Cytokine in the investigation of issues within Cellular differentiation. His STAT3 research includes themes of Interleukin 2 and Molecular biology. His work deals with themes such as Interleukin 12 and Interleukin 13, which intersect with Interleukin 3.
Arian Laurence focuses on Immunology, Cell biology, Immune system, Cancer research and Cellular differentiation. His research integrates issues of Cytotoxic T cell, IL-2 receptor and FOXP3 in his study of Cell biology. The Immune system study which covers Cell that intersects with Antigen.
His Cancer research study combines topics from a wide range of disciplines, such as Virus, PI3K/AKT/mTOR pathway and Retinoic acid. The study incorporates disciplines such as STAT6, Transcription factor, T cell, Transforming growth factor beta and Epigenetics in addition to Cellular differentiation. Arian Laurence usually deals with Transcription factor and limits it to topics linked to STAT3 and Molecular biology.
Arian Laurence mainly investigates Cancer research, Receptor, Cell biology, Immune system and Immunology. Arian Laurence combines subjects such as Downregulation and upregulation, TFEB, Virus, PD-L1 and PI3K/AKT/mTOR pathway with his study of Cancer research. His Receptor research is multidisciplinary, relying on both Retinoic acid receptor alpha, Interleukin 9, Transcription factor, Phenocopy and Glycoprotein 130.
His Cell biology research is multidisciplinary, incorporating perspectives in T cell, CD8 and Autophagosome formation. His study in Immune system is interdisciplinary in nature, drawing from both Cell, Cytokine, Proinflammatory cytokine, Retinoic acid and Allergic inflammation. He works on Immunology which deals in particular with Asthma.
His primary areas of study are Receptor, Cancer research, Macrophage, Glycoprotein 130 and Transmembrane domain. His biological study spans a wide range of topics, including Myeloid, Interferon, Complement system and Regulome. His work carried out in the field of Cancer research brings together such families of science as Cell culture, Apoptosis, Virus, Bronchoalveolar lavage and Flow cytometry.
His Macrophage study combines topics in areas such as Autophagy, Inflammasome, Protein subunit and Cell biology. His research on Glycoprotein 130 concerns the broader Immunology. His work on Transmembrane domain is being expanded to include thematically relevant topics such as Loss function.
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Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation
Arian Laurence;Cristina M. Tato;Todd S. Davidson;Yuka Kanno.
Immunity (2007)
Impaired T H 17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Joshua D. Milner;Jason M. Brenchley;Jason M. Brenchley;Arian Laurence;Alexandra F. Freeman.
Nature (2008)
Generation of pathogenic T H 17 cells in the absence of TGF-β signalling
Kamran Ghoreschi;Arian Laurence;Xiang-Ping Yang;Cristina M Tato.
Nature (2010)
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.
Jason S Stumhofer;Arian Laurence;Emma H Wilson;Elaine Huang.
Nature Immunology (2006)
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
Mandy J McGeachy;Yi Chen;Cristina M Tato;Arian Laurence.
Nature Immunology (2009)
Janus kinases in immune cell signaling.
Kamran Ghoreschi;Arian Laurence;John J. O’Shea.
Immunological Reviews (2009)
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
Jason S Stumhofer;Jonathan S Silver;Arian Laurence;Paige M Porrett.
Nature Immunology (2007)
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist
Ivona Aksentijevich;Seth L. Masters;Polly J. Ferguson;Paul Dancey.
The New England Journal of Medicine (2009)
IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner.
Lai Wei;Arian Laurence;Kevin M. Elias;Kevin M. Elias;John J. O'Shea.
Journal of Biological Chemistry (2007)
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.
Zhi Chen;Arian Laurence;Yuka Kanno;Margit Pacher-Zavisin.
Proceedings of the National Academy of Sciences of the United States of America (2006)
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