H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Immunology H-index 201 Citations 153,862 825 World Ranking 4 National Ranking 3
Medicine H-index 220 Citations 182,865 1,011 World Ranking 30 National Ranking 23

Research.com Recognitions

Awards & Achievements

2011 - Royal Netherlands Academy of Arts and Sciences

2009 - Albany Medical Center Prize in Medicine and Biomedical Research

1998 - Member of the National Academy of Sciences

1986 - Oswald Avery Award, Infectious Diseases Society of America

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Cytokine

His scientific interests lie mostly in Immunology, Interleukin, Cytokine, Internal medicine and Inflammation. His Interleukin research incorporates themes from Tumor necrosis factor alpha, Interleukin 1 receptor antagonist, Pathogenesis, Molecular biology and Peripheral blood mononuclear cell. Charles A. Dinarello studied Cytokine and Receptor that intersect with Cell biology and Cytotoxic T cell.

His Internal medicine study frequently links to related topics such as Endocrinology. His study looks at the relationship between Endocrinology and fields such as Receptor antagonist, as well as how they intersect with chemical problems. The Inflammation study which covers Blockade that intersects with Anakinra.

His most cited work include:

  • Biologic basis for interleukin-1 in disease (3792 citations)
  • Immunological and Inflammatory Functions of the Interleukin-1 Family (2323 citations)
  • Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1). (2278 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Immunology, Interleukin, Cytokine, Internal medicine and Inflammation. His Interleukin research incorporates elements of Interleukin 6, Molecular biology, Peripheral blood mononuclear cell, Pharmacology and Receptor antagonist. His biological study deals with issues like Receptor, which deal with fields such as Cell biology and Signal transduction.

His Internal medicine research includes themes of Gastroenterology, Endocrinology and Cardiology. His studies deal with areas such as Alpha and Beta as well as Endocrinology. His Inflammation study incorporates themes from Colitis, In vivo, Rheumatoid arthritis and Immunity.

He most often published in these fields:

  • Immunology (54.05%)
  • Interleukin (40.13%)
  • Cytokine (42.51%)

What were the highlights of his more recent work (between 2013-2021)?

  • Immunology (54.05%)
  • Inflammation (35.30%)
  • Cytokine (42.51%)

In recent papers he was focusing on the following fields of study:

Charles A. Dinarello mostly deals with Immunology, Inflammation, Cytokine, Internal medicine and Interleukin. In Immunology, Charles A. Dinarello works on issues like Anakinra, which are connected to Myocarditis and Adverse effect. Charles A. Dinarello focuses mostly in the field of Inflammation, narrowing it down to matters related to Receptor and, in some cases, Cell biology and Molecular biology.

His Cytokine research focuses on Cancer research and how it relates to Histone deacetylase. His study in Internal medicine is interdisciplinary in nature, drawing from both Gastroenterology, Endocrinology and Cardiology. The concepts of his Interleukin study are interwoven with issues in Colitis, Ex vivo, Signal transduction and Disease.

Between 2013 and 2021, his most popular works were:

  • Neuroinflammation in Alzheimer's disease (2213 citations)
  • Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial (403 citations)
  • Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial. (392 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Cytokine

His primary areas of investigation include Inflammation, Immunology, Cytokine, Internal medicine and Interleukin. His Inflammation study integrates concerns from other disciplines, such as Acquired immune system, Colitis and Gout. His Immunology research is multidisciplinary, incorporating perspectives in Receptor and Receptor antagonist.

His Cytokine research integrates issues from Tumor necrosis factor alpha, Cancer research, Arthritis, Chemokine and Signal transduction. His Internal medicine study combines topics in areas such as Endocrinology and Surgery. Charles A. Dinarello has included themes like Proinflammatory cytokine, Antibody, CD8 and TLR4 in his Interleukin study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

Biologic basis for interleukin-1 in disease

Charles A. Dinarello.
Blood (1996)

7406 Citations

Immunological and Inflammatory Functions of the Interleukin-1 Family

Charles A. Dinarello.
Annual Review of Immunology (2009)

3832 Citations

Interleukin-1 and interleukin-1 antagonism.

Charles A. Dinarello.
Blood (1991)

3419 Citations

Induction by IL 1 and interferon-gamma: tissue distribution, biochemistry, and function of a natural adherence molecule (ICAM-1).

Michael L. Dustin;Robert Rothlein;Atul K. Bhan;Charles A. Dinarello.
Journal of Immunology (1986)

3115 Citations

Neuroinflammation in Alzheimer's disease

Michael T Heneka;Monica J Carson;Joseph El Khoury;Gary E Landreth.
Lancet Neurology (2015)

2849 Citations

Biology of interleukin 1.

Charles A. Dinarello.
The FASEB Journal (1988)

2208 Citations

Detection of circulating tumor necrosis factor after endotoxin administration.

Hamish R. Michie;Kirk R. Manogue;David R. Spriggs;Arthur Revhaug.
The New England Journal of Medicine (1988)

2134 Citations

Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones

H Besedovsky;A del Rey;E Sorkin;CA Dinarello.
Science (1986)

2119 Citations

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

Charles A. Dinarello.
Blood (2011)

2012 Citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

Charles A. Dinarello;Joseph G. Cannon;Sheldon M. Wolff;Harry A. Bernheim.
Journal of Experimental Medicine (1986)

1923 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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