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Shizuo Akira

Shizuo Akira

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Best Scientists
2025
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Immunology
Japan
2026

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 309 1 1 1 1 1355 478811

Shizuo Akira publications per year

The chart shows the history of publications by Shizuo Akira between 1982 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Shizuo Akira published across 44 years, from 1982 to 2025, averaging 33.4 papers a year. Output peaked at 110 publications in 2006. 34 of the 1,471 publications appeared in the last two years.

No. of publications
25 50 75 100
Bar chart. Horizontal axis: year, 1982 to 2025. Vertical axis: number of publications, 0 to 110. Peak 110 publications in 2006. 1982: 1 publication 1983: 2 publications 1984: 2 publications 1985: 2 publications 1986: 0 publications 1987: 3 publications 1988: 1 publication 1989: 1 publication 1990: 5 publications 1991: 4 publications 1992: 13 publications 1993: 7 publications 1994: 3 publications 1995: 7 publications 1996: 11 publications 1997: 12 publications 1998: 18 publications 1999: 31 publications 2000: 48 publications 2001: 50 publications 2002: 47 publications 2003: 74 publications 2004: 93 publications 2005: 104 publications 2006: 110 publications 2007: 79 publications 2008: 97 publications 2009: 98 publications 2010: 86 publications 2011: 79 publications 2012: 55 publications 2013: 53 publications 2014: 45 publications 2015: 32 publications 2016: 20 publications 2017: 22 publications 2018: 18 publications 2019: 25 publications 2020: 16 publications 2021: 14 publications 2022: 17 publications 2023: 32 publications 2024: 23 publications 2025: 11 publications
1982 2025

1,471 publications in total across all disciplines

View publications per year as a table
Shizuo Akira: publications per year, 1982 to 2025
Year Publications
1982 1
1983 2
1984 2
1985 2
1986 0
1987 3
1988 1
1989 1
1990 5
1991 4
1992 13
1993 7
1994 3
1995 7
1996 11
1997 12
1998 18
1999 31
2000 48
2001 50
2002 47
2003 74
2004 93
2005 104
2006 110
2007 79
2008 97
2009 98
2010 86
2011 79
2012 55
2013 53
2014 45
2015 32
2016 20
2017 22
2018 18
2019 25
2020 16
2021 14
2022 17
2023 32
2024 23
2025 11
Total 1,471
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Shizuo Akira publications per year - data summary

  • Shizuo Akira, a Immunology scholar from Osaka University, has 1,471 publications recorded across 44 years, from 1982 to 2025.
  • The oldest publication on record dates to 1982 and the most recent to 2025.
  • The most productive year is 2006, with 110 publications.
  • The least productive years with any output are 1982, 1988 and 1989, with 1 publication each.
  • 1 of the 44 years in the span carries no publications at all (1986).
  • The rate of publication averages 33.4 papers per year over the whole span, or 34.2 per year counting only the 43 years with at least one publication.
  • The last 5 years on the chart (2021-2025) hold 97 publications, 7% of the career total.
  • Split into equal eras - 1982-1996: 62 publications (4.1 per year); 1997-2011: 1,026 publications (68.4 per year); 2012-2025: 383 publications (27.4 per year).
  • Comparing the opening and closing eras, the overall trend of publication is rising.

Shizuo Akira publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Shizuo Akira sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 807+ publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 1,355 publications — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100 1,355
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Shizuo Akira publication distribution in Immunology in 2026 - data summary

  • The chart plots the publication count of all 4,929 Immunology scientists ranked by Research.com in 2026, grouped into 76 ranges running from 62–71 to 807+ publications.
  • Shizuo Akira, a Immunology scholar from Osaka University, records 1,355 publications - the 100th percentile of the discipline.
  • 100% of ranked Immunology scientists score the same or lower than Shizuo Akira, and about 0% score higher.
  • The median of the discipline falls in the 242–251 publications range, and Shizuo Akira ranks above the median.
  • The most crowded range is 152–161 publications, holding 189 scientists (4% of the field).
  • 52% of the field sits in the lowest quarter of the value range (up to 242–251 publications), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 807 publications or more, 100 scientists in all (2% of the field).

Shizuo Akira D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Shizuo Akira sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 157+ D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 309 D-Index — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96 309
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Shizuo Akira D-index placement in Immunology in 2026 - data summary

  • The chart plots the discipline H-index (D-index) of all 4,929 Immunology scientists ranked by Research.com in 2026, grouped into 60 ranges running from 40–41 to 157+ D-Index.
  • Shizuo Akira, a Immunology scholar from Osaka University, records 309 D-Index - the 100th percentile of the discipline.
  • 100% of ranked Immunology scientists score the same or lower than Shizuo Akira, and about 0% score higher.
  • The median of the discipline falls in the 68–69 D-Index range, and Shizuo Akira ranks above the median.
  • The most crowded range is 58–59 D-Index, holding 201 scientists (4% of the field).
  • 50% of the field sits in the lowest quarter of the value range (up to 68–69 D-Index), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 157 D-Index or more, 96 scientists in all (2% of the field).

Research.com Recognitions

  • 2026 - Research.com Immunology in Japan Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Immunology in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award
  • 2022 - Research.com Immunology in Japan Leader Award
  • 2022 - Research.com Medicine in Japan Leader Award
  • 2011 - Canada Gairdner International Award
  • 2010 - Keio Medical Science Prize, Keio University, Tokyo, Japan
  • 2009 - Member of the National Academy of Sciences
  • 2004 - Robert Koch Prize

Overview

Shizuo Akira is primarily affiliated with Osaka University in Japan and has an extensive research portfolio focused on immunology, molecular biology, and medicine. Their work addresses various aspects of immune response, inflammation, and cytokine signaling pathways.

The scientist's recent papers include the following:

  • Decoding Toll-like receptors: Recent insights and perspectives in innate immunity (2024, Immunity)
  • CGRP sensory neurons promote tissue healing via neutrophils and macrophages (2024, Nature)
  • Control of RNA Stability in Immunity (2021, Annual Review of Immunology)
  • Eosinophils attenuate hepatic ischemia-reperfusion injury in mice through ST2-dependent IL-13 production (2021, Science Translational Medicine)
  • Local administration of regulatory T cells promotes tissue healing (2024, Nature Communications)

The main fields of study in Shizuo Akira's research output are:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Subfields of specialization include:

  • Immunology
  • Molecular Biology
  • Oncology
  • Pulmonary and Respiratory Medicine
  • Pharmacology

Key topics addressed in the scientist's research are:

  • Immune Response and Inflammation
  • IL-33, ST2, and ILC Pathways
  • Interferon and immune responses
  • Inflammatory mediators and NSAID effects
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • Cytokine Signaling Pathways and Interactions

Frequent co-authors of Shizuo Akira include:

  • Takashi Satoh
  • Atsushi Kumanogoh
  • Satoshi Uematsu
  • Kiyoharu Fukushima
  • Daisuke Motooka

The scientist's works are primarily published in venues such as:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • UNC Libraries
  • Nature Communications

Shizuo Akira has received multiple awards during their career, including the Canada Gairdner International Award (2011), Keio Medical Science Prize from Keio University in Tokyo (2010), membership in the National Academy of Sciences (2009), and the Robert Koch Prize (2004).

Best Publications

  • Pathogen Recognition and Innate Immunity

    Shizuo Akira;Satoshi Uematsu;Osamu Takeuchi

  • Toll-like receptors.

    Kiyoshi Takeda;Tsuneyasu Kaisho;Shizuo Akira

  • Toll-like receptor signalling

    Shizuo Akira;Kiyoshi Takeda

  • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

    Taro Kawai;Shizuo Akira

  • Pattern Recognition Receptors and Inflammation

    Osamu Takeuchi;Shizuo Akira

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • A Toll-like receptor recognizes bacterial DNA.

    Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  • Erratum A Toll-like receptor recognizes bacterial DNA

    Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  • Toll-like receptors: critical proteins linking innate and acquired immunity.

    Shizuo Akira;Kiyoshi Takeda;Tsuneyasu Kaisho

  • Toll-like receptors in innate immunity.

    Kiyoshi Takeda;Shizuo Akira

  • Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

    Florian Heil;Hiroaki Hemmi;Hubertus Hochrein;Franziska Ampenberger

  • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.

    Mitsutoshi Yoneyama;Mika Kikuchi;Takashi Natsukawa;Noriaki Shinobu

  • The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.

    Fumitaka Hayashi;Kelly D. Smith;Adrian Ozinsky;Thomas R. Hawn;Thomas R. Hawn

  • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.

    Katsuaki Hoshino;Osamu Takeuchi;Taro Kawai;Hideki Sanjo

  • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

    Hiroki Kato;Osamu Takeuchi;Shintaro Sato;Mitsutoshi Yoneyama

  • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.

    Sandra S. Diebold;Tsuneyasu Kaisho;Hiroaki Hemmi;Shizuo Akira

  • Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

    Taro Kawai;Shizuo Akira

  • Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

    Osamu Takeuchi;Katsuaki Hoshino;Taro Kawai;Hideki Sanjo

  • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

    Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Katsuaki Hoshino

  • TLR SIGNALING PATHWAYS

    Kiyoshi Takeda;Shizuo Akira

Frequent Co-Authors

Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Satoshi Uematsu
Satoshi Uematsu Osaka Metropolitan University
Osamu Takeuchi
Osamu Takeuchi Kyoto University
Taro Kawai
Taro Kawai Nara Institute of Science and Technology
Ken J. Ishii
Ken J. Ishii University of Tokyo
Masahiro Yamamoto
Masahiro Yamamoto Osaka University
Tatsuya Saitoh
Tatsuya Saitoh Osaka University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Tsuneyasu Kaisho
Tsuneyasu Kaisho Wakayama Medical University
Shintaro Sato
Shintaro Sato Osaka University

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Related Online Degrees & Career Pathways

For those interested in studying Immunology in the USA, pursuing related health science degrees can open diverse career pathways. Nursing, in particular, offers several accelerated and specialized programs that complement immunology knowledge.

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Non-nurses interested in entering the nursing field can explore the best online bsn programs for non nurses, which offer a solid foundational degree to complement immunology expertise.

Lastly, those seeking speedier educational routes might consider 12-month accelerated nursing programs, designed to quickly prepare students for the nursing workforce.

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