D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Immunology
Japan
2022

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 226 Citations 241,364 754 World Ranking 1 National Ranking 1
Medicine D-index 248 Citations 286,384 886 World Ranking 14 National Ranking 1
Best Scientists D-index 293 Citations 426,524 1,388 World Ranking 13 National Ranking 1

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

2022 - Research.com Medicine in Japan Leader Award

2022 - Research.com Immunology in Japan Leader Award

2011 - Canada Gairdner International Award

2010 - Keio Medical Science Prize, Keio University, Tokyo, Japan

2009 - Member of the National Academy of Sciences

2004 - Robert Koch Prize

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

His scientific interests lie mostly in Cell biology, Immunology, Innate immune system, Signal transduction and Receptor. His biological study spans a wide range of topics, including Acquired immune system and Toll-like receptor, Myeloid Differentiation Factor 88. His research on Innate immune system concerns the broader Immune system.

His Immune system study which covers Microbiology that intersects with TLR5 and Secretion. His work in Signal transduction tackles topics such as Transcription factor which are related to areas like Cancer research. As part of one scientific family, Shizuo Akira deals mainly with the area of Virology, narrowing it down to issues related to the RNA, and often Molecular biology.

His most cited work include:

  • Pathogen Recognition and Innate Immunity (8453 citations)
  • Toll-like receptor signalling (6463 citations)
  • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors (5702 citations)

What are the main themes of his work throughout his whole career to date?

Shizuo Akira mainly focuses on Cell biology, Immunology, Innate immune system, Immune system and Signal transduction. The study incorporates disciplines such as Receptor, Molecular biology and Myeloid Differentiation Factor 88 in addition to Cell biology. His study involves Toll-like receptor, Cytokine, Inflammation, Proinflammatory cytokine and TLR2, a branch of Immunology.

His studies in Innate immune system integrate themes in fields like Acquired immune system and Immunity. Within one scientific family, Shizuo Akira focuses on topics pertaining to Virology under Immune system, and may sometimes address concerns connected to RNA. Shizuo Akira interconnects Kinase and TRIF in the investigation of issues within Signal transduction.

He most often published in these fields:

  • Cell biology (35.88%)
  • Immunology (35.16%)
  • Innate immune system (22.09%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (35.88%)
  • Immunology (35.16%)
  • Immune system (20.22%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Immunology, Immune system, Innate immune system and Inflammation. Shizuo Akira combines subjects such as Autophagy, Receptor and Cytokine with his study of Cell biology. While the research belongs to areas of Immunology, Shizuo Akira spends his time largely on the problem of Virology, intersecting his research to questions surrounding RNA.

His biological study spans a wide range of topics, including Adjuvant, Antigen, Flagellin and Microbiology. His work deals with themes such as Acquired immune system, Molecular biology, Translation and Immunity, which intersect with Innate immune system. He interconnects TLR9, Cancer research and Endocrinology in the investigation of issues within Inflammation.

Between 2012 and 2021, his most popular works were:

  • Autophagy in infection, inflammation and immunity (1089 citations)
  • Correction: Stat3 Activation Is Responsible for IL-6–Dependent T Cell Proliferation through Preventing Apoptosis: Generation and Characterization of T Cell–Specific Stat3-Deficient Mice (549 citations)
  • Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome (455 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Enzyme

Shizuo Akira mainly investigates Cell biology, Immunology, Immune system, Autophagy and Innate immune system. His Cell biology research incorporates themes from Receptor, Inflammasome and Biochemistry. His study looks at the relationship between Immunology and fields such as Haematopoiesis, as well as how they intersect with chemical problems.

His Immune system study incorporates themes from Cancer research, Virology, RNA, Microbiology and Interleukin 12. T cell is closely connected to Molecular biology in his research, which is encompassed under the umbrella topic of Innate immune system. His Signal transduction research includes themes of Gene expression and Cellular differentiation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Pathogen Recognition and Innate Immunity

Shizuo Akira;Satoshi Uematsu;Osamu Takeuchi.
Cell (2006)

11616 Citations

Toll-like receptor signalling

Shizuo Akira;Kiyoshi Takeda.
Nature Reviews Immunology (2004)

9336 Citations

Toll-like receptors.

Kiyoshi Takeda;Tsuneyasu Kaisho;Shizuo Akira.
Annual Review of Immunology (2003)

8659 Citations

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Taro Kawai;Shizuo Akira.
Nature Immunology (2010)

7444 Citations

A Toll-like receptor recognizes bacterial DNA.

Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho.
Nature (2000)

7383 Citations

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham.
Autophagy (2012)

7068 Citations

Erratum A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho.
Nature (2001)

6785 Citations

Pattern Recognition Receptors and Inflammation

Osamu Takeuchi;Shizuo Akira.
Cell (2010)

6193 Citations

Toll-like receptors: critical proteins linking innate and acquired immunity.

Shizuo Akira;Kiyoshi Takeda;Tsuneyasu Kaisho.
Nature Immunology (2001)

5660 Citations

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.

Katsuaki Hoshino;Osamu Takeuchi;Taro Kawai;Hideki Sanjo.
Journal of Immunology (1999)

4233 Citations

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