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Immunology

D-Index
91
Citations
80434
World Ranking
1017
National Ranking
35

Overview

Tsuneyasu Kaisho is affiliated with Wakayama Medical University in Japan. Their research primarily spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Within these areas, the scientist has contributed significantly to topics including Immunotherapy and Immune Responses, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immune Response and Inflammation, CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, and Immune cells in cancer.

Their recent publications demonstrate a focus on immune regulation, cellular interactions, and cancer immunotherapy. Notable papers include:

  • "The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake," 2021, Immunity
  • "Thymic epithelial cells co-opt lineage-defining transcription factors to eliminate autoreactive T cells," 2022, Cell
  • "A vaccine targeting resistant tumours by dual T cell plus NK cell attack," 2022, Nature
  • "Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches," 2022, Immunity
  • "Effect of CpG Depletion of Vector Genome on CD8+ T Cell Responses in AAV Gene Therapy," 2021, Frontiers in Immunology

Kaisho's research is often published in prominent venues, with frequent contributions to:

  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • Nature Communications
  • Cell Reports

Collaborations form an important aspect of their work. Frequent coauthors include Izumi Sasaki, Hiroaki Hemmi, Yuri Fukuda-Ohta, Katsuaki Hoshino, and Takashi Tanaka, reflecting a diverse network of scientific partnerships.

Best Publications

  • Toll-like receptors.

    Kiyoshi Takeda;Tsuneyasu Kaisho;Shizuo Akira

  • A Toll-like receptor recognizes bacterial DNA.

    Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  • Erratum A Toll-like receptor recognizes bacterial DNA

    Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  • Toll-like receptors: critical proteins linking innate and acquired immunity.

    Shizuo Akira;Kiyoshi Takeda;Tsuneyasu Kaisho

  • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.

    Sandra S. Diebold;Tsuneyasu Kaisho;Hiroaki Hemmi;Shizuo Akira

  • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

    Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Katsuaki Hoshino

  • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway.

    Hiroaki Hemmi;Tsuneyasu Kaisho;Osamu Takeuchi;Shintaro Sato

  • Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

    Kiyoshi Takeda;Björn E Clausen;Tsuneyasu Kaisho;Tohru Tsujimura

  • TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

    Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Satoshi Uematsu

  • Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4

    Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Hideki Sanjo

  • Toll-like receptor function and signaling.

    Tsuneyasu Kaisho;Shizuo Akira

  • A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

    Takeshi Tanoue;Satoru Morita;Damian R. Plichta;Ashwin N. Skelly

  • Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma

    Edward W. Roberts;Miranda L. Broz;Mikhail Binnewies;Mark B. Headley

  • Correction: Stat3 Activation Is Responsible for IL-6–Dependent T Cell Proliferation through Preventing Apoptosis: Generation and Characterization of T Cell–Specific Stat3-Deficient Mice

    Kiyoshi Takeda;Tsuneyasu Kaisho;Nobuaki Yoshida;Junji Takeda

  • The roles of two IκB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

    Hiroaki Hemmi;Osamu Takeuchi;Shintaro Sato;Masahiro Yamamoto

  • Toll-like receptors as adjuvant receptors

    Tsuneyasu Kaisho;Shizuo Akira

  • Endotoxin-induced maturation of MyD88-deficient dendritic cells.

    Tsuneyasu Kaisho;Osamu Takeuchi;Taro Kawai;Katsuaki Hoshino

  • T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

    Akira Suzuki;Manae Tsukio Yamaguchi;Toshiaki Ohteki;Takehiko Sasaki

  • Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets

    Tomoki Ito;Ryuichi Amakawa;Tsuneyasu Kaisho;Hiroaki Hemmi

  • Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

    Alexander D. Edwards;Sandra S. Diebold;Emma Wetter Slack;Hideyuki Tomizawa

  • Toll-Like Receptors

    Himanshu Kumar;Kiyoshi Takeda;Shizuo Akira

Frequent Co-Authors

Shizuo Akira
Shizuo Akira Osaka University
Katsuaki Hoshino
Katsuaki Hoshino Kagawa University
Toshio Hirano
Toshio Hirano National Institutes for Quantum and Radiological Science and Technology
Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Osamu Takeuchi
Osamu Takeuchi Kyoto University
Shintaro Sato
Shintaro Sato Osaka University
Masahiro Yamamoto
Masahiro Yamamoto Osaka University
Taro Kawai
Taro Kawai Nara Institute of Science and Technology
Koji Hase
Koji Hase Keio University
Satoshi Uematsu
Satoshi Uematsu Osaka Metropolitan University

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