Katsuaki Hoshino

Overview

Best Publications

• A Toll-like receptor recognizes bacterial DNA.

  Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  8443
  Citations

• Erratum A Toll-like receptor recognizes bacterial DNA

  Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho

  6783
  Citations

• Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.

  Katsuaki Hoshino;Osamu Takeuchi;Taro Kawai;Hideki Sanjo

  4717
  Citations

• Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

  Osamu Takeuchi;Katsuaki Hoshino;Taro Kawai;Hideki Sanjo

  4277
  Citations

• Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

  Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Katsuaki Hoshino

  4156
  Citations

• Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway.

  Hiroaki Hemmi;Tsuneyasu Kaisho;Osamu Takeuchi;Shintaro Sato

  3324
  Citations

• Cutting Edge: Role of Toll-Like Receptor 1 in Mediating Immune Response to Microbial Lipoproteins

  Osamu Takeuchi;Shintaro Sato;Takao Horiuchi;Katsuaki Hoshino

  1787
  Citations

• Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.

  Masahiro Yamamoto;Shintaro Sato;Kiyotoshi Mori;Katsuaki Hoshino

  1675
  Citations

• Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes.

  Taro Kawai;Osamu Takeuchi;Takashi Fujita;Jun-ichiro Inoue

  1626
  Citations

• TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

  Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Satoshi Uematsu

  1454
  Citations

• Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4

  Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Hideki Sanjo

  1386
  Citations

• Cutting Edge: TLR2-Deficient and MyD88-Deficient Mice Are Highly Susceptible to Staphylococcus aureus Infection

  Osamu Takeuchi;Katsuaki Hoshino;Shizuo Akira

  1322
  Citations

• Cutting Edge: Preferentially the R-Stereoisomer of the Mycoplasmal Lipopeptide Macrophage-Activating Lipopeptide-2 Activates Immune Cells Through a Toll-Like Receptor 2- and MyD88-Dependent Signaling Pathway

  Osamu Takeuchi;Andreas Kaufmann;Karsten Grote;Taro Kawai

  875
  Citations

• The roles of two IκB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

  Hiroaki Hemmi;Osamu Takeuchi;Shintaro Sato;Masahiro Yamamoto

  866
  Citations

• Endotoxin-induced maturation of MyD88-deficient dendritic cells.

  Tsuneyasu Kaisho;Osamu Takeuchi;Taro Kawai;Katsuaki Hoshino

  751
  Citations

• Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.

  Hans Häcker;Ramunas M. Vabulas;Osamu Takeuchi;Katsuaki Hoshino

  669
  Citations

• Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ

  Masahiro Yamamoto;Soh Yamazaki;Satoshi Uematsu;Shintaro Sato

  641
  Citations

• IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

  Tomohiro Yoshimoto;Hiroko Tsutsui;Kouji Tominaga;Katsuaki Hoshino

  635
  Citations

• Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades.

  Osamu Takeuchi;Kiyoshi Takeda;Katsuaki Hoshino;Osamu Adachi

  464
  Citations

• IκB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9

  Katsuaki Hoshino;Takahiro Sugiyama;Mitsuru Matsumoto;Takashi Tanaka

  453
  Citations