D-Index & Metrics Best Publications
Microbiology
Japan
2023
Medicine
Japan
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 127 Citations 124,155 261 World Ranking 50 National Ranking 1
Medicine D-index 125 Citations 124,612 302 World Ranking 1693 National Ranking 37

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in Japan Leader Award

2023 - Research.com Microbiology in Japan Leader Award

2022 - Research.com Microbiology in Japan Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Immune system

Cell biology, Toll-like receptor, Signal transduction, TLR2 and Immune system are his primary areas of study. He interconnects Innate immune system, Cyclic GMP-AMP synthase, Myeloid Differentiation Factor 88 and Transcription factor in the investigation of issues within Cell biology. He has begun a study into Toll-like receptor, looking into Immunology and Receptor.

His research integrates issues of Inflammation and Interferon in his study of Signal transduction. The various areas that Osamu Takeuchi examines in his TLR2 study include Peptidoglycan, Interleukin 12 and Cytokine. The Immune system study combines topics in areas such as Interleukin-1 receptor, Regulation of gene expression and M2 Macrophage.

His most cited work include:

  • Pathogen Recognition and Innate Immunity (8453 citations)
  • A Toll-like receptor recognizes bacterial DNA. (5617 citations)
  • Pattern Recognition Receptors and Inflammation (4828 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Toll-like receptor, Signal transduction, Immunology and Molecular biology. His Cell biology study combines topics in areas such as Cellular differentiation, Transcription factor, Innate immune system, Immune system and Proinflammatory cytokine. Osamu Takeuchi combines subjects such as RNA and Gene expression with his study of Innate immune system.

His Toll-like receptor research incorporates elements of Cytokine and TLR4. The study incorporates disciplines such as Interferon, Kinase and Myeloid Differentiation Factor 88 in addition to Signal transduction. His studies deal with areas such as Messenger RNA and Effector as well as Molecular biology.

He most often published in these fields:

  • Cell biology (45.35%)
  • Toll-like receptor (21.92%)
  • Signal transduction (22.22%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (45.35%)
  • Messenger RNA (8.11%)
  • Immune system (16.52%)

In recent papers he was focusing on the following fields of study:

Osamu Takeuchi mostly deals with Cell biology, Messenger RNA, Immune system, RNA and Immunology. His Cell biology study incorporates themes from RNase P, Transcription factor, Receptor, Innate immune system and Regulation of gene expression. His work in the fields of Innate immune system, such as Pattern recognition receptor, overlaps with other areas such as Mechanism.

Osamu Takeuchi has researched Messenger RNA in several fields, including Molecular biology, Protein biosynthesis and Hepcidin. His biological study deals with issues like Post-transcriptional regulation, which deal with fields such as Tristetraprolin. Many of his studies on Immunology involve topics that are commonly interrelated, such as Signal transduction.

Between 2015 and 2021, his most popular works were:

  • Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells (94 citations)
  • Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells (94 citations)
  • Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration (62 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Immune system

His primary scientific interests are in Cell biology, Messenger RNA, RNA, Molecular biology and Innate immune system. His research in Cell biology intersects with topics in Three prime untranslated region, Receptor, RNase P and Immune system. His research investigates the connection between RNA and topics such as Regulation of gene expression that intersect with issues in Computational biology, Transcription, Gene expression, Gene expression profiling and Enhancer.

The various areas that Osamu Takeuchi examines in his Molecular biology study include Transferrin receptor, Transferrin, Iron-deficiency anemia, Endonuclease and Hepcidin. His Innate immune system research includes themes of Inflammation, Acquired immune system, Tristetraprolin and Protein biosynthesis. His Pattern recognition receptor research includes elements of Immune receptor, Toll-like receptor and Pathogenesis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Pathogen Recognition and Innate Immunity

Shizuo Akira;Satoshi Uematsu;Osamu Takeuchi.
Cell (2006)

13388 Citations

Pattern Recognition Receptors and Inflammation

Osamu Takeuchi;Shizuo Akira.
Cell (2010)

8129 Citations

A Toll-like receptor recognizes bacterial DNA.

Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho.
Nature (2000)

7984 Citations

Erratum A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi;Osamu Takeuchi;Taro Kawai;Tsuneyasu Kaisho.
Nature (2001)

6782 Citations

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product.

Katsuaki Hoshino;Osamu Takeuchi;Taro Kawai;Hideki Sanjo.
Journal of Immunology (1999)

4517 Citations

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.

Osamu Takeuchi;Katsuaki Hoshino;Taro Kawai;Hideki Sanjo.
Immunity (1999)

4057 Citations

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato;Osamu Takeuchi;Shintaro Sato;Mitsutoshi Yoneyama.
Nature (2006)

4027 Citations

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

Masahiro Yamamoto;Shintaro Sato;Hiroaki Hemmi;Katsuaki Hoshino.
Science (2003)

3811 Citations

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway.

Hiroaki Hemmi;Tsuneyasu Kaisho;Osamu Takeuchi;Shintaro Sato.
Nature Immunology (2002)

3102 Citations

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai;Ken Takahashi;Ken Takahashi;Shintaro Sato;Cevayir Coban.
Nature Immunology (2005)

2906 Citations

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