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Genetics

D-Index
55
Citations
32758
World Ranking
3532
National Ranking
1532

Overview

Alexei A. Aravin is affiliated with the California Institute of Technology in the United States. Their research lies primarily within the fields of Biochemistry, Genetics, and Molecular Biology, with a substantial focus on Molecular Biology.

Their work covers a diverse range of subfields including Plant Science, Genetics, Ecology, and Parasitology. Key research topics encompass CRISPR and Genetic Engineering, Chromosomal and Genetic Variations, Advanced biosensing and bioanalysis techniques, Bacteriophages and microbial interactions, Ubiquitin and proteasome pathways, Bacterial Genetics and Biotechnology, as well as Genomics and Chromatin Dynamics.

Frequent publication venues for their research include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Nature Communications
  • eLife
  • Molecular Cell

Among their recent papers are the following:

  • "DNA targeting and interference by a bacterial Argonaute nuclease", 2020, Nature
  • "A programmable pAgo nuclease with universal guide and target specificity from the mesophilic bacterium Kurthia massiliensis", 2021, Nucleic Acids Research
  • "piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline", 2021, Genes & Development
  • "Genome-wide DNA sampling by Ago nuclease from the cyanobacterium Synechococcus elongatus", 2020, RNA Biology
  • "Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity", 2022, Nature Communications

They have collaborated frequently with several co-authors, including:

  • Andrey Kulbachinskiy
  • Daria Esyunina
  • Anton Kuzmenko
  • Maria Ninova
  • Peiwei Chen

Best Publications

  • A mammalian microRNA expression atlas based on small RNA library sequencing.

    Pablo Landgraf;Mirabela Rusu;Robert Sheridan;Alain Sewer;Alain Sewer

  • Human MicroRNA Targets

    Bino John;Anton James Enright;Anton James Enright;Alexei Aravin;Thomas Tuschl

  • Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila

    Julius Brennecke;Alexei A. Aravin;Alexander Stark;Monica Dus

  • A novel class of small RNAs bind to MILI protein in mouse testes

    Alexei Aravin;Dimos Gaidatzis;Sébastien Pfeffer;Sébastien Pfeffer;Sébastien Pfeffer;Mariana Lagos-Quintana

  • PIWI-interacting small RNAs: the vanguard of genome defence.

    Mikiko C. Siomi;Kaoru Sato;Dubravka Pezic;Alexei A. Aravin

  • A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice.

    Alexei A. Aravin;Alexei A. Aravin;Ravi Sachidanandam;Ravi Sachidanandam;Deborah Bourc'his;Christopher Schaefer;Christopher Schaefer

  • The Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race

    Alexei A. Aravin;Gregory J. Hannon;Julius Brennecke

  • Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

    Oliver H. Tam;Alexei A. Aravin;Paula Stein;Angelique Girard

  • The small RNA profile during Drosophila melanogaster development

    Alexei A. Aravin;Mariana Lagos-Quintana;Abdullah Yalcin;Mihaela Zavolan

  • Developmentally Regulated piRNA Clusters Implicate MILI in Transposon Control

    Alexei A. Aravin;Ravi Sachidanandam;Angelique Girard;Katalin Fejes-Toth

  • Clustering and conservation patterns of human microRNAs

    Yael Altuvia;Pablo Landgraf;Gila Lithwick;Naama Elefant

  • Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline

    Alexei A. Aravin;Natalia M. Naumova;Alexei V. Tulin;Vasilii V. Vagin

  • An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

    Julius Brennecke;Colin D. Malone;Alexei A. Aravin;Ravi Sachidanandam

  • Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state

    Adrien Le Thomas;Alicia K. Rogers;Alexandre Webster;Georgi K. Marinov

  • Identification and characterization of small RNAs involved in RNA silencing

    Alexei Aravin;Thomas Tuschl

  • Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members

    Vasily V. Vagin;James Wohlschlegel;Jun Qu;Zophonias Jonsson

  • Identification of clustered microRNAs using an ab initio prediction method

    Alain Sewer;Nicodème Paul;Pablo Landgraf;Alexei Aravin

  • Cytoplasmic Compartmentalization of the Fetal piRNA Pathway in Mice

    Alexei A. Aravin;Godfried W. van der Heijden;Julio Castañeda;Vasily V. Vagin

  • The histone chaperone CAF-1 safeguards somatic cell identity

    Sihem Cheloufi;Sihem Cheloufi;Ulrich Elling;Barbara Hopfgartner;Youngsook L. Jung;Youngsook L. Jung

  • piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells

    Dubravka Pezic;Sergei A. Manakov;Ravi Sachidanandam;Alexei A. Aravin

Frequent Co-Authors

Gregory J. Hannon
Gregory J. Hannon University of Cambridge
Ravi Sachidanandam
Ravi Sachidanandam Icahn School of Medicine at Mount Sinai
Thomas Tuschl
Thomas Tuschl Rockefeller University
Julius Brennecke
Julius Brennecke Austrian Academy of Sciences
Déborah Bourc'his
Déborah Bourc'his Institute Curie
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Chris Sander
Chris Sander Harvard University
Mihaela Zavolan
Mihaela Zavolan University of Basel
Michael J. Brownstein
Michael J. Brownstein National Institutes of Health
Debora S. Marks
Debora S. Marks Harvard University

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