World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
73
Citations
22586
World Ranking
2030
National Ranking
929

Research.com Recognitions

  • 2018 - Member of the National Academy of Sciences
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Haifan Lin is affiliated with Yale University in the United States and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology, focusing particularly on Molecular Biology and Plant Science. Their research also spans Genetics, Cancer Research, and Hematology.

The scientist's work covers numerous main topics including:

  • Chromosomal and Genetic Variations
  • RNA modifications and cancer
  • RNA Research and Splicing
  • RNA and protein synthesis mechanisms
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • Plant Virus Research Studies

Haifan Lin has published multiple recent papers such as:

  • Roles of piRNAs in transposon and pseudogene regulation of germline mRNAs and lncRNAs, 2021, Genome Biology
  • Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus, 2022, Nature Neuroscience
  • PIWIL1 promotes gastric cancer via a piRNA-independent mechanism, 2020, Proceedings of the National Academy of Sciences
  • Development of a Brigatinib degrader (SIAIS117) as a potential treatment for ALK positive cancer resistance, 2020, European Journal of Medicinal Chemistry
  • Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies, 2022, Molecular Cell

Frequent co-authors collaborating with Haifan Lin include:

  • Nils Neuenkirchen
  • Matthew D. Simon
  • Karla M. Neugebauer
  • Joshua T. Zimmer
  • Sanhong Liu

Their work has appeared frequently in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Proceedings of the National Academy of Sciences
  • Molecular Cell
  • PubMed

Haifan Lin has been recognized by election as a Member of the National Academy of Sciences in 2018. Additionally, they were named a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • miwi, a Murine Homolog of piwi, Encodes a Cytoplasmic Protein Essential for Spermatogenesis

    Wei Deng;Haifan Lin

  • A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal.

    Daniel N. Cox;Anna Chao;Jeff Baker;Lisa Chang

  • A novel class of small RNAs in mouse spermatogenic cells

    Shane T. Grivna;Ergin Beyret;Zhong Wang;Haifan Lin

  • A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary

    Haifan Lin;Allan C. Spradling

  • MicroRNAs: key regulators of stem cells.

    Vamsi K. Gangaraju;Haifan Lin

  • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

    Satomi Kuramochi-Miyagawa;Tohru Kimura;Takashi W. Ijiri;Taku Isobe

  • The Biogenesis and Function of PIWI Proteins and piRNAs: Progress and Prospect

    Travis Thomson;Haifan Lin

  • The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation

    Haifan Lin;Lin Yue;Allan C. Spradling

  • piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells

    Daniel N. Cox;Anna Chao;Haifan Lin

  • MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis

    Shane T. Grivna;Brook Pyhtila;Haifan Lin

  • The stem-cell niche theory: lessons from flies

    Haifan Lin

  • PIWI proteins and PIWI-interacting RNAs in the soma

    Robert J. Ross;Molly M. Weiner;Haifan Lin

  • An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster

    Hang Yin;Haifan Lin;Haifan Lin

  • Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.

    Toshiaki Watanabe;Toshiaki Watanabe;Shin Ichi Tomizawa;Shin Ichi Tomizawa;Kohzoh Mitsuya;Yasushi Totoki

  • Drosophila PIWI associates with chromatin and interacts directly with HP1a

    Brent Brower-Toland;Seth D. Findley;Seth D. Findley;Ling Jiang;Li Liu

  • Uniting germline and stem cells: the function of Piwi proteins and the piRNA pathway in diverse organisms.

    Celina Juliano;Jianquan Wang;Haifan Lin

  • Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas.

    Dan Qiao;Anne-Marie Zeeman;Wei Deng;Leendert H J Looijenga

  • HEDGEHOG IS REQUIRED FOR THE PROLIFERATION AND SPECIFICATION OF OVARIAN SOMATIC CELLS PRIOR TO EGG CHAMBER FORMATION IN DROSOPHILA

    Alexandria J. Forbes;Haifan Lin;Philip W. Ingham;Allan C. Spradling

  • Spectrosomes and Fusomes Anchor Mitotic Spindles during Asymmetric Germ Cell Divisions and Facilitate the Formation of a Polarized Microtubule Array for Oocyte Specification inDrosophila

    Wei Deng;Haifan Lin

  • Germline Stem Cell Division and Egg Chamber Development in Transplanted Drosophila Germaria

    Haifan Lin;Allan C. Spradling

Frequent Co-Authors

Hang Yin
Hang Yin Tsinghua University
Hongyu Zhao
Hongyu Zhao Yale University
Michael Snyder
Michael Snyder Stanford University
Toru Nakano
Toru Nakano Osaka University
Hiroyuki Sasaki
Hiroyuki Sasaki Kyushu University
Karla M. Neugebauer
Karla M. Neugebauer Yale University
Robert Steele
Robert Steele University of California, Irvine
Asao Fujiyama
Asao Fujiyama National Institute of Genetics
Chi Zhang
Chi Zhang Hohai University
Atsushi Toyoda
Atsushi Toyoda National Institute of Genetics

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