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Toru Nakano

Toru Nakano

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
97
Citations
35991
World Ranking
591
National Ranking
44

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award
  • 2016 - Fellow of Biomaterials Science and Engineering

Overview

Toru Nakano is affiliated with Osaka University in Japan and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Molecular Biology, Genetics, Plant Science, Surgery, and Nuclear and High Energy Physics.

Their scientific work covers several main topics including:

  • Epigenetics and DNA Methylation
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • Chromosomal and Genetic Variations
  • DNA Repair Mechanisms
  • RNA modifications and cancer
  • Cancer-related gene regulation

Notable recent papers authored by Nakano include:

  • Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells (2021, PLoS Genetics)
  • MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells (2021, Scientific Reports)
  • DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells (2024, BMC Genomics)
  • Ribosomal stress induces 2-cell embryo-like state transition of the mouse ESCs through p53 activation (2021, Biochemical and Biophysical Research Communications)
  • Effects of transgene insertion loci and copy number on Dnmt3L gene silencing through antisense transgene-derived PIWI-interacting RNAs (2022, RNA)

Nakano has frequently collaborated with a number of co-authors, including:

  • Shinpei Yamaguchi
  • Takahiro Maeda
  • Satomi Kuramochi-Miyagawa
  • Takaaki Tatsuguchi
  • Shingo Kozono

Their work has appeared in diverse publication venues such as:

  • PLoS Genetics
  • Scientific Reports
  • BMC Genomics
  • Biochemical and Biophysical Research Communications
  • RNA

Among professional recognitions, Nakano was awarded the title of Fellow of Biomaterials Science and Engineering in 2016.

Best Publications

  • A novel class of small RNAs bind to MILI protein in mouse testes

    Alexei Aravin;Dimos Gaidatzis;Sébastien Pfeffer;Sébastien Pfeffer;Sébastien Pfeffer;Mariana Lagos-Quintana

  • Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

    Toshiaki Watanabe;Toshiaki Watanabe;Yasushi Totoki;Atsushi Toyoda;Masahiro Kaneda;Masahiro Kaneda

  • Generation of lymphohematopoietic cells from embryonic stem cells in culture

    Toru Nakano;Hiroaki Kodama;Tasuku Honjo

  • DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

    Satomi Kuramochi-Miyagawa;Toshiaki Watanabe;Kengo Gotoh;Yasushi Totoki

  • Characterization of the piRNA Complex from Rat Testes

    Nelson C. Lau;Anita G. Seto;Jinkuk Kim;Satomi Kuramochi-Miyagawa

  • Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins.

    Kei Tashiro;Hideaki Tada;Ralf Heilker;Michio Shirozu

  • 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

    Mark Wossidlo;Toshinobu Nakamura;Konstantin Lepikhov;C. Joana Marques

  • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

    Satomi Kuramochi-Miyagawa;Tohru Kimura;Takashi W. Ijiri;Taku Isobe

  • Structure and Chromosomal Localization of the Human Stromal Cell-Derived Factor 1 (SDF1) Gene

    Michio Shirozu;Toru Nakano;Johji Inazawa;Kei Tashiro

  • Conservation of the Notch signalling pathway in mammalian neurogenesis

    J.L. Pompa de la;A. Wakeham;K.M. Correia;E. Samper

  • Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

    Yasuo Horie;Akira Suzuki;Ei Kataoka;Takehiko Sasaki

  • T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

    Akira Suzuki;Manae Tsukio Yamaguchi;Toshiaki Ohteki;Takehiko Sasaki

  • Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

    T Nakano;T Sonoda;C Hayashi;A Yamatodani

  • Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses.

    Hiroyuki Nishimura;Nagahiro Minato;Toru Nakano;Tasuku Honjo

  • PGC7/Stella protects against DNA demethylation in early embryogenesis.

    Toshinobu Nakamura;Yoshikazu Arai;Hiroki Umehara;Masaaki Masuhara

  • Identification of the Product of Growth Arrest-specific Gene 6 as a Common Ligand for Axl, Sky, and Mer Receptor Tyrosine Kinases

    Kyoko Nagata;Kazumasa Ohashi;Toru Nakano;Hitoshi Arita

  • Disruption of the mouse RBP-J kappa gene results in early embryonic death

    C. Oka;T. Nakano;A. Wakeham;J.L. de la Pompa

  • Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells.

    Kenji Tanigaki;Hua Han;Norio Yamamoto;Kei Tashiro

  • PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

    Toshinobu Nakamura;Yu-Jung Liu;Hiroyuki Nakashima;Hiroki Umehara

  • Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.

    Toshiaki Watanabe;Toshiaki Watanabe;Shin Ichi Tomizawa;Shin Ichi Tomizawa;Kohzoh Mitsuya;Yasushi Totoki

Frequent Co-Authors

Akira Suzuki
Akira Suzuki Kobe University
Yukihiko Kitamura
Yukihiko Kitamura Osaka University
Tasuku Honjo
Tasuku Honjo Kyoto University
Takehiko Sasaki
Takehiko Sasaki Tokyo Medical and Dental University
Yuzuru Kanakura
Yuzuru Kanakura Osaka University
Hiroyuki Sasaki
Hiroyuki Sasaki Kyushu University
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Kei Tashiro
Kei Tashiro Kyoto Prefectural University of Medicine
Hitoshi Arita
Hitoshi Arita Shionogi (Japan)
Atsuo Ogura
Atsuo Ogura University of Tsukuba

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