World's Best Scientists 2026 revealed!
Hiroyuki Sasaki

Hiroyuki Sasaki

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Genetics

D-Index
87
Citations
32106
World Ranking
1202
National Ranking
47

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Hiroyuki Sasaki is affiliated with Kyushu University in Japan and has contributed to research primarily in the fields of Medicine and Earth and Planetary Sciences. Their work spans several subfields including Atmospheric Science, Molecular Biology, Physiology, Oceanography, and Public Health, Environmental and Occupational Health.

The scientist's research topics cover a diverse range of subjects. These include:

  • Gut microbiota and health
  • Diet and metabolism studies
  • Arctic and Antarctic ice dynamics
  • Cryospheric studies and observations
  • Oceanographic and Atmospheric Processes
  • Nutritional Studies and Diet
  • Blood groups and transfusion

Hiroyuki Sasaki has published in multiple peer-reviewed venues, with frequent contributions to the following journals:

  • Scientific Reports
  • Frontiers in Microbiology
  • Food Science & Nutrition

The scientist's recent papers reflect their interdisciplinary interests and include:

  • "Reversal of freshening trend of Antarctic Bottom Water in the Australian-Antarctic Basin during 2010s" (2020), published in Scientific Reports
  • "Effectiveness of personalized granola tailored to the gut microbiota for improving gut environment and mood states" (2025), published in Frontiers in Microbiology
  • "Perinatal outcomes in RhD-negative pregnant women in Japan" (2025), published in Scientific Reports
  • "Evaluation of the Fermentation Characteristics of Prebiotic-Containing Granola and Short-Chain Fatty Acid Production in an In Vitro Gut Microbiota Model" (2025), published in Food Science & Nutrition

Collaboration is a part of their research practice, working frequently with several other researchers. Notable coauthors of Hiroyuki Sasaki include:

  • Hirofumi Masutomi
  • Katsuyuki Ishihara
  • Shigeru Aoki
  • Kaihe Yamazaki
  • Daisuke Hirano

The scope of Sasaki's research encompasses understanding both human health aspects related to gut microbiota and diet, as well as broader environmental and geological phenomena such as Antarctic ice dynamics and atmospheric processes. This reflects a multidisciplinary approach bridging molecular and physiological studies with earth and environmental sciences.

Best Publications

  • Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

    Masahiro Kaneda;Masaki Okano;Kenichiro Hata;Takashi Sado;Takashi Sado;Takashi Sado

  • Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands

    Mitinori Saitou;Mikio Furuse;Hiroyuki Sasaki;Jörg-Dieter Schulzke

  • Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

    Toshiaki Watanabe;Toshiaki Watanabe;Yasushi Totoki;Atsushi Toyoda;Masahiro Kaneda;Masahiro Kaneda

  • Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells.

    Mikio Furuse;Kyoko Furuse;Hiroyuki Sasaki;Shoichiro Tsukita

  • DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

    Satomi Kuramochi-Miyagawa;Toshiaki Watanabe;Kengo Gotoh;Yasushi Totoki

  • Epigenetic events in mammalian germ-cell development: reprogramming and beyond

    Hiroyuki Sasaki;Yasuhisa Matsui

  • Targets and dynamics of promoter DNA methylation during early mouse development

    Julie Borgel;Sylvain Guibert;Yufeng Li;Yufeng Li;Hatsune Chiba

  • Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

    Toshiaki Watanabe;Atsushi Takeda;Atsushi Takeda;Tomoyuki Tsukiyama;Kazuyuki Mise

  • Derivation of Human Trophoblast Stem Cells

    Hiroaki Okae;Hidehiro Toh;Tetsuya Sato;Hitoshi Hiura

  • Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse

    Yuzuru Kato;Masahiro Kaneda;Masahiro Kaneda;Kenichiro Hata;Kenichiro Hata;Kenji Kumaki

  • Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia.

    Shin Ichi Mizuno;Takahito Chijiwa;Takashi Okamura;Koichi Akashi

  • Parental-origin-specific epigenetic modification of the mouse H19 gene.

    Anne C. Ferguson-Smith;Anne C. Ferguson-Smith;Hiroyuki Sasaki;Hiroyuki Sasaki;Bruce M. Cattanach;Bruce M. Cattanach;M. Azim Surani;M. Azim Surani

  • Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development

    Ryutaro Hirasawa;Hatsune Chiba;Hatsune Chiba;Masahiro Kaneda;Masahiro Kaneda;Shoji Tajima

  • Genomic Imprinting and Physiological Processes in Mammals.

    Valter Tucci;Anthony R. Isles;Gavin Kelsey;Gavin Kelsey;Anne C. Ferguson-Smith

  • Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions

    Masahiko Itoh;Hiroyuki Sasaki;Mikio Furuse;Harunobu Ozaki

  • Aberrant DNA methylation of imprinted loci in sperm from oligospermic patients.

    Hisato Kobayashi;Akiko Sato;Eiko Otsu;Hitoshi Hiura

  • Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.

    Toshiaki Watanabe;Toshiaki Watanabe;Shin Ichi Tomizawa;Shin Ichi Tomizawa;Kohzoh Mitsuya;Yasushi Totoki

  • Genomic organization of the human-amyloid beta-protein precursor gene.

    Shun ichi Yoshikai;Hiroyuki Sasaki;Katsumi Doh-ura;Hirokazu Furuya

  • Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

    Hideki Sumimoto;Youhko Kage;Hiroyuki Nunoi;Hiroyuki Sasaki

  • Parental-origin-specific epigenetic modification of the mouse H19 gene

    A.C. Ferguson-Smith;H. Sasaki;B.M. Cattanach;M.A. Surani

Frequent Co-Authors

Yoshiyuki Sakaki
Yoshiyuki Sakaki Toyohashi University of Technology
Toru Nakano
Toru Nakano Osaka University
Mitinori Saitou
Mitinori Saitou Kyoto University
Yoshiyuki Sakaki
Yoshiyuki Sakaki Toyohashi University of Technology
Atsushi Toyoda
Atsushi Toyoda National Institute of Genetics
En Li
En Li Harvard University
Anne C. Ferguson-Smith
Anne C. Ferguson-Smith University of Cambridge
Takuya Yamamoto
Takuya Yamamoto Kyoto University
robert feil
robert feil Centre national de la recherche scientifique, CNRS
Katsuhiko Hayashi
Katsuhiko Hayashi Osaka University

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