Her main research concerns Genetics, Epigenetics, Reprogramming, DNA methylation and Genomic imprinting. Her Epigenetics study combines topics from a wide range of disciplines, such as Mutation, 5-Methylcytosine and CpG site. The various areas that Wendy Dean examines in her Reprogramming study include Embryonic stem cell, Cellular differentiation, Somatic cell, Transcription factor and Demethylation.
In general DNA methylation study, her work on Epigenomics often relates to the realm of Somatic cell nuclear transfer, thereby connecting several areas of interest. Within one scientific family, Wendy Dean focuses on topics pertaining to RNA-Directed DNA Methylation under Epigenomics, and may sometimes address concerns connected to Histone H2A. Her Genomic imprinting research incorporates themes from Andrology and Cell biology.
Genetics, DNA methylation, Epigenetics, Genomic imprinting and Reprogramming are her primary areas of study. The study incorporates disciplines such as Chromatin, Methylation, Cellular differentiation and Somatic cell in addition to DNA methylation. Her study focuses on the intersection of Methylation and fields such as Molecular biology with connections in the field of Base excision repair.
Her Epigenetics study integrates concerns from other disciplines, such as Epigenomics, Germline, CpG site and Cell biology. The concepts of her Genomic imprinting study are interwoven with issues in Phenotype, Regulation of gene expression, Imprinting and Allele. Her Reprogramming study also includes fields such as
Her primary areas of investigation include Cell biology, DNA methylation, Epigenetics, Cell fate determination and Reprogramming. Wendy Dean has included themes like Genetics, Enhancer, Transcription factor, Chromatin and Epiblast in her Cell biology study. Her work on Cell as part of her general Genetics study is frequently connected to Transcriptional noise, thereby bridging the divide between different branches of science.
Her DNA methylation study frequently draws connections to adjacent fields such as Cellular differentiation. Her work investigates the relationship between Epigenetics and topics such as Neuroscience that intersect with problems in Epigenesis. The Reprogramming study combines topics in areas such as Induced pluripotent stem cell, Germline and Epigenome.
Wendy Dean spends much of her time researching Genetics, DNA methylation, Chromatin, Cell biology and Methylation. Many of her research projects under Genetics are closely connected to Transcriptional noise with Transcriptional noise, tying the diverse disciplines of science together. Her research in Epigenetics intersects with topics in Cell potency, Transcription factor and Stem cell.
Her research on DNA methylation focuses in particular on Genomic imprinting. Her work focuses on many connections between Cell biology and other disciplines, such as Cell fate determination, that overlap with her field of interest in Epiblast, Gastrulation, Embryo and Primitive streak. Her work carried out in the field of Methylation brings together such families of science as Molecular biology, Cell adhesion and Cellular differentiation.
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Epigenetic Reprogramming in Mammalian Development
Wolf Reik;Wendy Dean;Jörn Walter.
Epigenetic reprogramming in mammals
Hugh D. Morgan;Fátima Santos;Kelly Green;Wendy Dean.
Human Molecular Genetics (2005)
Dynamic reprogramming of DNA methylation in the early mouse embryo.
Fátima Santos;Brian Hendrich;Wolf Reik;Wendy Dean.
Developmental Biology (2002)
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure
Takashi Nagano;Yaniv Lubling;Tim J. Stevens;Stefan Schoenfelder.
Conservation of methylation reprogramming in mammalian development: aberrant reprogramming in cloned embryos.
Wendy Dean;Fátima Santos;Miodrag Stojkovic;Valeri Zakhartchenko.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Active demethylation of the paternal genome in the mouse zygote.
J. Oswald;S Engemann;N Lane;W. Mayer.
Current Biology (2000)
Placental-specific IGF-II is a major modulator of placental and fetal growth
Miguel Constância;Myriam Hemberger;Jennifer Hughes;Wendy Dean.
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by Aid deficiency
Christian Popp;Wendy Dean;Suhua Feng;Shawn J. Cokus.
The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells
Stefanie Seisenberger;Simon Andrews;Felix Krueger;Julia Arand.
Molecular Cell (2012)
Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse
Natasha Lane;Wendy Dean;Sylvia Erhardt;Petra Hajkova.
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