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Genetics

D-Index
79
Citations
29221
World Ranking
1625
National Ranking
749

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Marisa S. Bartolomei is affiliated with the University of Pennsylvania in the United States and specializes in research intersecting biochemistry, genetics, molecular biology, and medicine. Their work primarily focuses on molecular biology, pediatrics, perinatology, child health, genetics, public health, environmental and occupational health, as well as health, toxicology, and mutagenesis.

Their key research topics include:

  • Epigenetics and DNA Methylation
  • Genetic Syndromes and Imprinting
  • Prenatal Screening and Diagnostics
  • Birth, Development, and Health
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive Biology and Fertility
  • RNA modifications and cancer

Their recent publications feature studies on various aspects of epigenetic regulation and developmental biology. Representative papers include:

  • "DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse," 2022, Cell Genomics
  • "Environmental Exposure to Endocrine Disrupting Chemicals Influences Genomic Imprinting, Growth, and Metabolism," 2021, Genes
  • "Modeling human epigenetic disorders in mice: Beckwith-Wiedemann Syndrome and Silver-Russell Syndrome," 2020, Disease Models & Mechanisms
  • "Human embryo live imaging reveals nuclear DNA shedding during blastocyst expansion and biopsy," 2023, Cell
  • "Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency," 2020, Molecular Cell

Frequent publication venues for Bartolomei's research include bioRxiv (Cold Spring Harbor Laboratory) with 12 publications, Human Molecular Genetics with 3, UNC Libraries with 3, Genes & Development with 2, and Molecular Cell with 2 publications.

Collaborative work involves several frequently associated co-authors with significant joint publications, such as:

  • Eric A. Rhon-Calderón (14 joint publications)
  • Yemin Lan (12 joint publications)
  • Joanne L. Thorvaldsen (9 joint publications)
  • Rexxi D. Prasasya (9 joint publications)
  • Rahul M. Kohli (9 joint publications)

Marisa S. Bartolomei was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2014.

Best Publications

  • Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

    Han Cho;James Mu;Jason K. Kim;Jason K. Kim;Joanne L. Thorvaldsen

  • Parental imprinting of the mouse H19 gene.

    Marisa S. Bartolomei;Sharon Zemel;Shirley M. Tilghman

  • Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair.

    Salvatore Cortellino;Jinfei Xu;Mara Sannai;Robert Moore

  • Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

    Joanne L. Thorvaldsen;Kristen L. Duran;Marisa S. Bartolomei

  • X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

    Jeannie T. Lee;Marisa S. Bartolomei

  • Genomic imprinting in mammals.

    Marisa S. Bartolomei;Shirley M. Tilghman

  • Differential Effects of Culture on Imprinted H19 Expression in the Preimplantation Mouse Embryo

    Adam S. Doherty;Adam S. Doherty;Mellissa R.W. Mann;Kimberly D. Tremblay;Marisa S. Bartolomei

  • Genomic Imprinting in Mammals

    Denise P. Barlow;Marisa S. Bartolomei

  • Mammalian Genomic Imprinting

    Marisa S. Bartolomei;Anne C. Ferguson-Smith

  • Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.

    M. S. Bartolomei;A. L. Webber;M. E. Brunkow;Shirley Marie Tilghman

  • Gene-specific timing and epigenetic memory in oocyte imprinting

    Diana Lucifero;Mellissa R.W. Mann;Marisa S. Bartolomei;Jacquetta M. Trasler

  • Genomic Imprinting and Physiological Processes in Mammals.

    Valter Tucci;Anthony R. Isles;Gavin Kelsey;Gavin Kelsey;Anne C. Ferguson-Smith

  • The H19 methylation imprint is erased and re‐established differentially on the parental alleles during male germ cell development

    Tamara L. Davis;Grace J. Yang;John R. McCarrey;Marisa S. Bartolomei

  • Selective loss of imprinting in the placenta following preimplantation development in culture.

    Mellissa R. W. Mann;Susan S. Lee;Adam S. Doherty;Raluca I. Verona

  • A paternal-specific methylation imprint marks the alleles of the mouse H19 gene.

    Kimberly D. Tremblay;Jennifer R. Saam;Robert S. Ingram;Shirley M. Tilghman

  • Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators

    William Stedman;Hyojeung Kang;Shu Lin;Joseph L Kissil

  • A 5’ 2 kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development

    Kimberly D. Tremblay;Kristen L. Duran;Marisa S. Bartolomei

  • Transgenic RNAi Reveals Essential Function for CTCF in H19 Gene Imprinting

    Andrew M. Fedoriw;Paula Stein;Paula Stein;Petr Svoboda;Petr Svoboda;Richard M. Schultz;Richard M. Schultz

  • Disruption of Imprinted Gene Methylation and Expression in Cloned Preimplantation Stage Mouse Embryos

    Mellissa R.W. Mann;Young Gie Chung;Leisha D. Nolen;Raluca I. Verona

  • Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development

    Rocío M. Rivera;Paula Stein;Jamie R. Weaver;Jesse Mager

Frequent Co-Authors

Richard M. Schultz
Richard M. Schultz University of Pennsylvania
Christos Coutifaris
Christos Coutifaris University of Pennsylvania
Shelley L. Berger
Shelley L. Berger University of Pennsylvania
John R. McCarrey
John R. McCarrey The University of Texas at San Antonio
Ryuzo Yanagimachi
Ryuzo Yanagimachi University of Hawaii at Manoa
Benjamin A. Garcia
Benjamin A. Garcia Washington University in St. Louis
Keith E. Latham
Keith E. Latham Michigan State University
Shirley M. Tilghman
Shirley M. Tilghman Princeton University
Paul M. Lieberman
Paul M. Lieberman The Wistar Institute
Anne C. Ferguson-Smith
Anne C. Ferguson-Smith University of Cambridge

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