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Genetics

D-Index
93
Citations
38250
World Ranking
964
National Ranking
474

Research.com Recognitions

  • 2015 - Member of the National Academy of Sciences
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jeannie T. Lee is affiliated with Harvard University in the United States. Their research is primarily situated in the field of Biochemistry, Genetics and Molecular Biology, with 123 publications recorded. Within this broad area, their work focuses mainly on Molecular Biology, Genetics, Plant Science, Cancer Research, and Surgery as notable subfields.

The scientist's research addresses multiple main topics, including RNA modifications and cancer, RNA research and splicing, genomics and chromatin dynamics, genetic and clinical aspects of sex determination and chromosomal abnormalities, cancer-related molecular mechanisms research, RNA and protein synthesis mechanisms, and chromosomal and genetic variations.

Jeannie T. Lee has contributed to several frequently represented publication venues, with multiple papers appearing in bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Nature Communications, Molecular Cell, and Cell.

Their recent papers include:

  • Long non-coding RNAs: definitions, functions, challenges and recommendations, 2023, Nature Reviews Molecular Cell Biology
  • Targeting Xist with compounds that disrupt RNA structure and X inactivation, 2022, Nature
  • Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding, 2020, Nature Communications
  • Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops, 2021, Cell
  • Xist Repeats A and B Account for Two Distinct Phases of X Inactivation Establishment, 2020, Developmental Cell

The scientist frequently collaborates with:

  • Barry Kesner
  • Hun-Goo Lee
  • Andrea J. Kriz
  • Roy Blum
  • Yong-Woo Lee

Jeannie T. Lee has been recognized with membership in the National Academy of Sciences since 2015 and was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • Long noncoding RNAs: past, present, and future.

    Johnny T Y Kung;David Colognori;David Colognori;Jeannie T Lee;Jeannie T Lee

  • Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

    Jing Zhao;Bryan K. Sun;Bryan K. Sun;Jennifer A. Erwin;Jennifer A. Erwin;Ji Joon Song

  • Epigenetic Regulation by Long Noncoding RNAs

    Jeannie T. Lee

  • Tsix , a gene antisense to Xist at the X-inactivation centre

    Jeannie T. Lee;Lance S. Davidow;David Warshawsky

  • Genome-wide identification of Polycomb-associated RNAs by RIP-seq

    Jing Zhao;Toshiro K. Ohsumi;Johnny T. Kung;Johnny T. Kung;Yuya Ogawa;Yuya Ogawa

  • Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

    Dawang Zhou;Claudius Conrad;Fan Xia;Ji Sun Park

  • X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

    Jeannie T. Lee;Marisa S. Bartolomei

  • Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

    Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Matthew J. Wakefield;Bronwen Aken;Chris T. Amemiya

  • Targeted Mutagenesis of Tsix Leads to Nonrandom X Inactivation

    Jeannie T. Lee;Naifang Lu

  • YY1 Tethers Xist RNA to the Inactive X Nucleation Center

    Yesu Jeon;Jeannie T. Lee

  • The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation.

    Di Tian;Sha Sun;Sha Sun;Jeannie T. Lee;Jeannie T. Lee

  • X chromosome dosage compensation: how mammals keep the balance

    Bernhard Payer;Jeannie T. Lee

  • Transient Homologous Chromosome Pairing Marks the Onset of X Inactivation

    Na Xu;Chia-Lun Tsai;Jeannie T. Lee

  • Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice

    Eda Yildirim;James E. Kirby;Diane E. Brown;Francois E. Mercier

  • Inheritance of a pre-inactivated paternal X chromosome in early mouse embryos

    Khanh D. Huynh;Jeannie T. Lee

  • A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

    Anand Minajigi;John E. Froberg;Chunyao Wei;Hongjae Sunwoo

  • Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

    Jeannie T. Lee

  • LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint

    Nadya Dimitrova;Jesse R. Zamudio;Robyn M. Jong;Dylan Soukup

  • Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations

    Christopher J. Lengner;Alexander A. Gimelbrant;Jennifer A. Erwin;Jennifer A. Erwin;Albert Wu Cheng

  • A 450 kb transgene displays properties of the mammalian X-inactivation center.

    Jeannie T Lee;Jeannie T Lee;William M Strauss;Jessica A Dausman;Rudolf Jaenisch

Frequent Co-Authors

Ruslan I. Sadreyev
Ruslan I. Sadreyev Harvard University
John L. Rinn
John L. Rinn University of Colorado Boulder
Amy J. Wagers
Amy J. Wagers Harvard University
Robert E. Kingston
Robert E. Kingston Harvard University
James Lee
James Lee The Francis Crick Institute
Steven A. Carr
Steven A. Carr Broad Institute
Marisa S. Bartolomei
Marisa S. Bartolomei University of Pennsylvania
Wilhelm Haas
Wilhelm Haas Harvard University

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