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Genetics
France
2024
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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Genetics

D-Index
89
Citations
38694
World Ranking
1104
National Ranking
39

Research.com Recognitions

  • 2024 - Research.com Genetics in France Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2021 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine
  • 2017 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale
  • 2013 - Fellow of the Royal Society, United Kingdom
  • 2012 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Edith Heard is affiliated with Collège de France in France and specializes in the fields of Biochemistry, Genetics, and Molecular Biology. Their body of work includes 98 published papers primarily focused on molecular biology, genetics, and related subfields such as plant science, cancer research, and immunology.

The main topics explored in their research are diverse and include:

  • Genomics and Chromatin Dynamics
  • CRISPR and Genetic Engineering
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Chromosomal and Genetic Variations
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • RNA Research and Splicing

Edith Heard has frequently published in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • L'annuaire du Collège de France
  • Nature Communications
  • Nature
  • Cell

Among their recent scholarly contributions are several papers of note:

  • Gene regulation in time and space during X-chromosome inactivation, published in 2022 by Nature Reviews Molecular Cell Biology
  • SPEN integrates transcriptional and epigenetic control of X-inactivation, published in 2020 by Nature
  • Parental-to-embryo switch of chromosome organization in early embryogenesis, published in 2020 by Nature
  • Xist nucleates local protein gradients to propagate silencing across the X chromosome, published in 2021 by Cell
  • Molecular Mechanisms of Facultative Heterochromatin Formation: An X-Chromosome Perspective, published in 2020 by Annual Review of Biochemistry

The scientist has coauthored extensively with the following frequent collaborators:

  • Nicolas Servant
  • Agnese Loda
  • Samuel Collombet
  • Rafael Galupa
  • Katia Ancelin

Edith Heard has also contributed to book publications, including the 2024 edition of Epigenetics and Cellular Memory, published by Collège de France eBooks.

In recognition of their research contributions, Edith Heard has received a range of scientific awards, including:

  • German National Academy of Sciences Leopoldina (2021) for Human Genetics and Molecular Medicine
  • Grand prix de l'Inserm (2017)
  • Fellow of the Royal Society, United Kingdom (2013)
  • Member of Academia Europaea (2012)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Spatial partitioning of the regulatory landscape of the X-inactivation centre

    Elphège P. Nora;Bryan R. Lajoie;Edda G. Schulz;Luca Giorgetti;Luca Giorgetti;Luca Giorgetti

  • Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.

    Masashi Narita;Sabrina Nuñez;Sabrina Nuñez;Edith Heard;Masako Narita

  • HiC-Pro: an optimized and flexible pipeline for Hi-C data processing

    Nicolas Servant;Nelle Varoquaux;Nelle Varoquaux;Nelle Varoquaux;Bryan R. Lajoie;Eric Viara

  • Transgenerational Epigenetic Inheritance: myths and mechanisms

    Edith Heard;Edith Heard;Robert A. Martienssen;Robert A. Martienssen

  • Advances in epigenetics link genetics to the environment and disease

    Giacomo Cavalli;Edith Heard

  • Systematic Discovery of Xist RNA Binding Proteins

    Ci Chu;Ci Chu;Qiangfeng Cliff Zhang;Simão Teixeira da Rocha;Ryan A. Flynn

  • Epigenetic dynamics of imprinted X inactivation during early mouse development.

    Ikuhiro Okamoto;Arie P. Otte;C. David Allis;Danny Reinberg

  • X-chromosome inactivation: counting, choice and initiation

    Philip Avner;Edith Heard

  • X-CHROMOSOME INACTIVATION IN MAMMALS

    Edith Heard;Philippe Clerc;Philip Avner

  • A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced

    Julie Chaumeil;Patricia Le Baccon;Anton Wutz;Edith Heard

  • Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin.

    Emily Bernstein;Elizabeth M. Duncan;Osamu Masui;Jesus Gil

  • Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation.

    Edith Heard;Claire Rougeulle;Danielle Arnaud;Philip Avner

  • Dosage compensation in mammals: fine-tuning the expression of the X chromosome

    Edith Heard;Christine M. Disteche

  • Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes

    Barbara A. Boggs;Peter Cheung;Edith Heard;Edith Heard;David L. Spector

  • Predictive Polymer Modeling Reveals Coupled Fluctuations in Chromosome Conformation and Transcription

    Luca Giorgetti;Luca Giorgetti;Luca Giorgetti;Rafael Galupa;Rafael Galupa;Rafael Galupa;Elphège P. Nora;Tristan Piolot;Tristan Piolot;Tristan Piolot

  • Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

    Ikuhiro Okamoto;Catherine Patrat;Dominique Thepot;Nathalie Peynot

  • Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts.

    Tilo Kunath;Tilo Kunath;Danielle Arnaud;Gary D. Uy;Ikuhiro Okamoto

  • Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation.

    Christian P. Bacher;Michèele Guggiari;Benedikt Brors;Sandrine Augui

  • Structural organization of the inactive X chromosome in the mouse

    Luca Giorgetti;Luca Giorgetti;Bryan R. Lajoie;Ava C. Carter;Mikael Attia

  • Regulation of X-chromosome inactivation by the X-inactivation centre

    Sandrine Augui;Elphège P. Nora;Edith Heard

Frequent Co-Authors

Emmanuel Barillot
Emmanuel Barillot Institute Curie
Philip Avner
Philip Avner European Bioinformatics Institute
Job Dekker
Job Dekker University of Massachusetts Chan Medical School
Neil Brockdorff
Neil Brockdorff University of Oxford
Howard Y. Chang
Howard Y. Chang Amgen (United States)
Mitinori Saitou
Mitinori Saitou Kyoto University
C. David Allis
C. David Allis Rockefeller University
Peter Fraser
Peter Fraser Florida State University
Wolf Reik
Wolf Reik Babraham Institute

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