D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 80 Citations 29,613 203 World Ranking 1010 National Ranking 36

Research.com Recognitions

Awards & Achievements

2021 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine

2017 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale

2013 - Fellow of the Royal Society, United Kingdom

2012 - Member of Academia Europaea

Member of the European Molecular Biology Organization (EMBO)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Genetics

Edith Heard mostly deals with Genetics, X-inactivation, XIST, X chromosome and Chromatin. Her Genetics research incorporates elements of Data processing and Computational science. Her studies deal with areas such as Cellular differentiation, Reprogramming, Molecular biology, Transcription and Epigenetics as well as X-inactivation.

Her study in XIST is interdisciplinary in nature, drawing from both Tsix, RNA, Non-coding RNA and Histone. In her study, E2F and Retinoblastoma is strongly linked to Heterochromatin, which falls under the umbrella field of X chromosome. In her work, Computational biology and Chromosome is strongly intertwined with Chromosome conformation capture, which is a subfield of Chromatin.

Her most cited work include:

  • Spatial partitioning of the regulatory landscape of the X-inactivation centre (1875 citations)
  • Spatial partitioning of the regulatory landscape of the X-inactivation centre (1875 citations)
  • Spatial partitioning of the regulatory landscape of the X-inactivation centre (1875 citations)

What are the main themes of her work throughout her whole career to date?

Genetics, X-inactivation, XIST, X chromosome and Chromatin are her primary areas of study. Genetics is represented through her Gene, Regulation of gene expression, Locus, Chromosome conformation capture and Chromosome research. Her X-inactivation research includes themes of Molecular biology, Epigenetics, Cellular differentiation and Dosage compensation.

Her studies in XIST integrate themes in fields like Tsix, RNA, Heterochromatin, Gene silencing and Transcription. She has researched X chromosome in several fields, including Yeast artificial chromosome, DNA methylation and Somatic cell. The study incorporates disciplines such as Histone, Genome, Computational biology and Cell biology in addition to Chromatin.

She most often published in these fields:

  • Genetics (81.30%)
  • X-inactivation (65.04%)
  • XIST (55.69%)

What were the highlights of her more recent work (between 2018-2021)?

  • XIST (55.69%)
  • X-inactivation (65.04%)
  • Chromatin (48.37%)

In recent papers she was focusing on the following fields of study:

The scientist’s investigation covers issues in XIST, X-inactivation, Chromatin, Cell biology and RNA. The various areas that Edith Heard examines in her XIST study include Tsix, Heterochromatin, Transcription and Locus. Her work carried out in the field of X-inactivation brings together such families of science as Gene silencing and Epigenetics.

Her Chromatin research integrates issues from Evolutionary biology, Histone, Dosage compensation, Fluorescence in situ hybridization and Regulation of gene expression. Her work in Histone addresses subjects such as Chromosome conformation capture, which are connected to disciplines such as Genomic organization. Her work deals with themes such as Chromatin Loop, CTCF and Cohesin, which intersect with Cell biology.

Between 2018 and 2021, her most popular works were:

  • Advances in epigenetics link genetics to the environment and disease (241 citations)
  • Advances in epigenetics link genetics to the environment and disease (241 citations)
  • The Implication of Early Chromatin Changes in X Chromosome Inactivation (95 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genome

Her scientific interests lie mostly in Chromatin, X-inactivation, XIST, Epigenetics and Regulation of gene expression. Her Chromatin research is multidisciplinary, incorporating perspectives in Histone and Genomic imprinting. Her Histone study introduces a deeper knowledge of Genetics.

Her X-inactivation research includes elements of Dosage compensation and Cell biology. Her XIST study frequently draws connections to adjacent fields such as RNA. Her biological study deals with issues like Transcription, which deal with fields such as Ectopic expression, Tsix and RNA polymerase II.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Spatial partitioning of the regulatory landscape of the X-inactivation centre

Elphège P. Nora;Bryan R. Lajoie;Edda G. Schulz;Luca Giorgetti;Luca Giorgetti;Luca Giorgetti.
Nature (2012)

2582 Citations

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.

Masashi Narita;Sabrina Nuñez;Sabrina Nuñez;Edith Heard;Masako Narita.
Cell (2003)

2350 Citations

Transgenerational Epigenetic Inheritance: myths and mechanisms

Edith Heard;Edith Heard;Robert A. Martienssen;Robert A. Martienssen.
Cell (2014)

1460 Citations

HiC-Pro: an optimized and flexible pipeline for Hi-C data processing

Nicolas Servant;Nelle Varoquaux;Nelle Varoquaux;Nelle Varoquaux;Bryan R. Lajoie;Eric Viara.
Genome Biology (2015)

1139 Citations

Epigenetic dynamics of imprinted X inactivation during early mouse development.

Ikuhiro Okamoto;Arie P. Otte;C. David Allis;Danny Reinberg.
Science (2004)

908 Citations

X-chromosome inactivation: counting, choice and initiation

Philip Avner;Edith Heard.
Nature Reviews Genetics (2001)

893 Citations

Systematic Discovery of Xist RNA Binding Proteins

Ci Chu;Ci Chu;Qiangfeng Cliff Zhang;Simão Teixeira da Rocha;Ryan A. Flynn.
Cell (2015)

859 Citations

X-CHROMOSOME INACTIVATION IN MAMMALS

Edith Heard;Philippe Clerc;Philip Avner.
Annual Review of Genetics (1997)

692 Citations

A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced

Julie Chaumeil;Patricia Le Baccon;Anton Wutz;Edith Heard.
Genes & Development (2006)

648 Citations

Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation.

Edith Heard;Claire Rougeulle;Danielle Arnaud;Philip Avner.
Cell (2001)

619 Citations

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