2026 Denis Duboule: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Genetics	100	754	710	20	18	286	35040
Molecular Biology	100	532	476	10	9	286	35040

Research.com Recognitions

2026 - Research.com Molecular Biology in France Leader Award
2024 - Research.com Genetics in France Leader Award
2024 - Research.com Genetics and Molecular Biology in France Leader Award
2023 - Research.com Genetics and Molecular Biology in France Leader Award
2022 - Research.com Genetics and Molecular Biology in France Leader Award
2012 - Member of the National Academy of Sciences
2012 - Fellow of the Royal Society, United Kingdom
2010 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale
2006 - Fellow of the American Academy of Arts and Sciences
2000 - Royal Netherlands Academy of Arts and Sciences
1996 - Member of Academia Europaea
Member of the European Molecular Biology Organization (EMBO)
Member of the European Molecular Biology Organization (EMBO)
Member of the European Molecular Biology Organization (EMBO)

Overview

Denis Duboule is affiliated with the Collège de France in France and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology. Their research spans several subfields including Molecular Biology, Plant Science, Genetics, Developmental Biology, and Cell Biology, reflecting a broad engagement with biological sciences.

The main topics of their work include:

Genomics and Chromatin Dynamics
Developmental Biology and Gene Regulation
RNA Research and Splicing
Chromosomal and Genetic Variations
Plant Molecular Biology Research
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Animal Genetics and Reproduction

The scientist has published research in several prominent venues, frequently contributing to:

bioRxiv (Cold Spring Harbor Laboratory)
L'annuaire du Collège de France
Development
Proceedings of the National Academy of Sciences
Genes & Development

Among recent papers authored or co-authored by them are:

"The regulatory landscapes of developmental genes", 2020, Development
"Chromatin topology and the timing of enhancer function at the HoxD locus", 2020, Proceedings of the National Academy of Sciences
"Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster", 2021, Genes & Development
"Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos", 2023, Nature Genetics
"The (unusual) heuristic value of Hox gene clusters; a matter of time?", 2022, Developmental Biology

Frequent co-authors collaborating with Denis Duboule include:

Lucille Lopez-Delisle
Bénédicte Mascrez
Christopher Chase Bolt
Sandra Gitto
Aurélie Hintermann

Denis Duboule has been recognized with multiple awards and distinctions, such as:

Fellow of the Royal Society, United Kingdom, 2012
Member of the National Academy of Sciences, 2012
Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale, 2010
Fellow of the American Academy of Arts and Sciences, 2006
Royal Netherlands Academy of Arts and Sciences, 2000
Member of Academia Europaea, 1996
Member of the European Molecular Biology Organization (EMBO)

Best Publications

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator.

Nicolas Preitner;Francesca Damiola;Luis-Lopez-Molina;Joszef Zakany

2465
Citations
The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes

D. Duboule;P. Dollé

1138
Citations
Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation.

Pascal Dollé;Juan-Carlos Izpisúa-Belmonte;Hildegard Falkenstein;Armand Renucci

733
Citations
Temporal colinearity and the phylotypic progression: a basis for the stability of a vertebrate Bauplan and the evolution of morphologies through heterochrony

Denis Duboule

726
Citations
Organizing Axes in Time and Space; 25 Years of Colinear Tinkering

Marie Kmita;Denis Duboule

631
Citations
Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs

Pascal Dollé;Andrée Dierich;Marianne LeMeur;Thomas Schimmang

587
Citations
The rise and fall of Hox gene clusters

Denis Duboule

579
Citations
Topology of mammalian developmental enhancers and their regulatory landscapes

Wouter de Laat;Denis Duboule;Denis Duboule

569
Citations
A Regulatory Archipelago Controls Hox Genes Transcription in Digits

Thomas Montavon;Natalia Soshnikova;Bénédicte Mascrez;Elisabeth Joye

558
Citations
A Global Control Region Defines a Chromosomal Regulatory Landscape Containing the HoxD Cluster

François Spitz;Federico Gonzalez;Denis Duboule

554
Citations
Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPARβ mutant mice

Liliane Michalik;Béatrice Desvergne;Nguan Soon Tan;Sharmila Basu-Modak

540
Citations
Colinearity and functional hierarchy among genes of the homeotic complexes

Denis Duboule;Gines Morata

540
Citations
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

Freek J. Vonk;Freek J. Vonk;Freek J. Vonk;Nicholas R. Casewell;Nicholas R. Casewell;Christiaan V. Henkel;Alysha M. Heimberg

511
Citations
Expression of the homeobox Hox-4 genes and the specification of position in chick wing development

J. C. Izpisua-Belmonte;C. Tickle;P. Dolle;L. Wolpert

490
Citations
A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs

Guillaume Andrey;Thomas Montavon;Bénédicte Mascrez;Federico Gonzalez

486
Citations
The role of Hox genes during vertebrate limb development

Jozsef Zakany;Denis Duboule;Denis Duboule

470
Citations
The Dynamic Architecture of Hox Gene Clusters

Daan Noordermeer;Marion Leleu;Erik Splinter;Jacques Rougemont;Jacques Rougemont

459
Citations
Considerations when investigating lncRNA function in vivo

Andrew R Bassett;Asifa Akhtar;Denise P Barlow;Adrian P Bird

441
Citations
Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

Leonardo Beccari;Naomi Moris;Mehmet Girgin;David A. Turner

431
Citations
Guidebook to the homeobox genes

Denis Duboule

424
Citations

Frequent Co-Authors

Yann Herault Institute of Genetics and Molecular and Cellular Biology

Robb Krumlauf Stowers Institute for Medical Research

Cheryll Tickle University of Bath

Pascal Dollé Institute of Genetics and Molecular and Cellular Biology

Pierre Chambon Institute of Genetics and Molecular and Cellular Biology

Michel C. Milinkovitch University of Geneva

Rolf Zeller University of Basel

Wouter de Laat Utrecht University

Stefan Mundlos Max Planck Society

Stylianos E. Antonarakis University of Geneva

External Links

Wikipedia of Denis Duboule Personal website of Denis Duboule

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