What is he best known for?
The fields of study he is best known for:
Denis Duboule mostly deals with Genetics, Gene, Hox gene, Homeobox and Regulation of gene expression.
HOXD13, Transcription, Homeotic gene, Genome and Locus are the core of his Genetics study.
His Gene study frequently draws connections to adjacent fields such as Evolutionary biology.
His Hox gene study combines topics from a wide range of disciplines, such as Vertebrate, Gene cluster, Limb development and Cell biology.
His work on HNF1B, EMX2 and Iroquois homeobox factor as part of general Homeobox study is frequently connected to Order and Acanthostega, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His biological study spans a wide range of topics, including Chromatin, Ectoderm, Subfamily and Hindbrain.
His most cited work include:
- The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator (1634 citations)
- The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes (711 citations)
- Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation. (515 citations)
What are the main themes of his work throughout his whole career to date?
Denis Duboule mainly investigates Hox gene, Genetics, Gene, Enhancer and Regulation of gene expression.
His Hox gene research incorporates themes from Evolutionary biology, Homeobox, Vertebrate, Chromatin and Cell biology.
His Vertebrate research includes themes of Morphogenesis and Anatomy.
His study in Transcription, Phenotype, Genome, Transgene and Gene cluster is carried out as part of his studies in Genetics.
His Gene study is mostly concerned with Locus, Limb development, Gene expression, Regulatory sequence and Transcription factor.
His study in Enhancer is interdisciplinary in nature, drawing from both Computational biology and Transcriptional regulation.
He most often published in these fields:
- Hox gene (86.52%)
- Genetics (82.75%)
- Gene (85.18%)
What were the highlights of his more recent work (between 2016-2021)?
- Gene (85.18%)
- Enhancer (48.79%)
- Chromatin (43.40%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Gene, Enhancer, Chromatin, Hox gene and Cell biology.
His Gene research entails a greater understanding of Genetics.
His Enhancer research integrates issues from Phenotype, Computational biology and Limb development.
The various areas that he examines in his Chromatin study include Developmental biology, CTCF, Regulatory sequence and Genomics.
Within one scientific family, Denis Duboule focuses on topics pertaining to CRISPR under Hox gene, and may sometimes address concerns connected to Long non-coding RNA.
His study on Ectoderm, Limb bud and Progenitor cell is often connected to Growth differentiation factor as part of broader study in Cell biology.
Between 2016 and 2021, his most popular works were:
- Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids (156 citations)
- Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids (156 citations)
- The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes (83 citations)
In his most recent research, the most cited papers focused on:
Denis Duboule mainly focuses on Enhancer, Gene, Hox gene, Chromatin and CTCF.
His work carried out in the field of Enhancer brings together such families of science as Computational biology and Limb development.
His Gene study is focused on Genetics in general.
His work on Mutant and Embryonic stem cell as part of general Genetics study is frequently linked to Alternative strategy, bridging the gap between disciplines.
His Hox gene research includes elements of Mesoderm and Cell biology.
His research investigates the connection between Chromatin and topics such as Developmental biology that intersect with problems in Regulatory sequence, Transcriptional response, Stem cell, Neuroscience and Genomics.
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