D-Index & Metrics Best Publications
Genetics and Molecular Biology
Singapore
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 102 Citations 48,583 261 World Ranking 406 National Ranking 3

Research.com Recognitions

Awards & Achievements

2022 - Research.com Genetics and Molecular Biology in Singapore Leader Award

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Internal medicine

His primary areas of investigation include Peroxisome proliferator-activated receptor, Receptor, Endocrinology, Internal medicine and Nuclear receptor. The subject of his Peroxisome proliferator-activated receptor research is within the realm of Biochemistry. His study in Receptor is interdisciplinary in nature, drawing from both Transcription factor, Cell growth and Epidermis, Cell biology.

As a member of one scientific family, he mostly works in the field of Endocrinology, focusing on Fatty liver and, on occasion, Fatty acid homeostasis and Steatosis. In his study, Tumor necrosis factor alpha is inextricably linked to Cancer research, which falls within the broad field of Internal medicine. Walter Wahli has researched Nuclear receptor in several fields, including Coactivator, Peroxisome proliferator, Phylogenetics and SUPERFAMILY.

His most cited work include:

  • Peroxisome proliferator-activated receptors: nuclear control of metabolism. (2654 citations)
  • Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat (1935 citations)
  • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ (1885 citations)

What are the main themes of his work throughout his whole career to date?

Walter Wahli focuses on Peroxisome proliferator-activated receptor, Internal medicine, Endocrinology, Receptor and Nuclear receptor. His Peroxisome proliferator-activated receptor research integrates issues from Peroxisome proliferator-activated receptor delta, Transcription factor, Peroxisome proliferator-activated receptor alpha and Cell biology. His work on Inflammation, Adipocyte, White adipose tissue and Fatty acid metabolism as part of general Internal medicine research is often related to FGF21, thus linking different fields of science.

As part of his studies on Endocrinology, Walter Wahli often connects relevant subjects like Fatty liver. His work in the fields of Receptor, such as Peroxisome, overlaps with other areas such as Fibrate. His Nuclear receptor study combines topics in areas such as Regulation of gene expression and Keratinocyte.

He most often published in these fields:

  • Peroxisome proliferator-activated receptor (74.19%)
  • Internal medicine (68.17%)
  • Endocrinology (66.24%)

What were the highlights of his more recent work (between 2016-2021)?

  • Internal medicine (68.17%)
  • Peroxisome proliferator-activated receptor (74.19%)
  • Endocrinology (66.24%)

In recent papers he was focusing on the following fields of study:

Walter Wahli mostly deals with Internal medicine, Peroxisome proliferator-activated receptor, Endocrinology, Receptor and Cell biology. Within one scientific family, Walter Wahli focuses on topics pertaining to Fatty acid under Internal medicine, and may sometimes address concerns connected to Liver cell. His Peroxisome proliferator-activated receptor research is multidisciplinary, relying on both Steatosis, Inflammation, Transcription factor, Downregulation and upregulation and Fatty liver.

In general Endocrinology study, his work on Lipid metabolism and Skeletal muscle often relates to the realm of FGF21, thereby connecting several areas of interest. His Receptor research incorporates elements of Nuclear receptor, Carbohydrate metabolism and Angiogenesis. His studies in Cell biology integrate themes in fields like Insulin receptor, Cell culture, Biogenesis and Gene expression.

Between 2016 and 2021, his most popular works were:

  • Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models (70 citations)
  • The gut microbiota influences skeletal muscle mass and function in mice (59 citations)
  • The gut microbiota influences skeletal muscle mass and function in mice (59 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Internal medicine

His main research concerns Internal medicine, Endocrinology, Peroxisome proliferator-activated receptor, Receptor and Fatty liver. His research on Internal medicine frequently connects to adjacent areas such as Gut flora. Walter Wahli has researched Endocrinology in several fields, including Neuromuscular junction and Downregulation and upregulation.

His Peroxisome proliferator-activated receptor study combines topics from a wide range of disciplines, such as Peroxisome, Lipid metabolism and Fatty acid metabolism. The Peroxisome study combines topics in areas such as Physiology and Cell biology. His research investigates the link between Receptor and topics such as Transcription factor that cross with problems in Knockout mouse and PPAR agonist.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Peroxisome proliferator-activated receptors: nuclear control of metabolism.

Béatrice Desvergne;Walter Wahli.
Endocrine Reviews (1999)

3921 Citations

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

O Braissant;F Foufelle;C Scotto;M Dauça.
Endocrinology (1996)

2762 Citations

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Steven A. Kliewer;Scott S. Sundseth;Stacey A. Jones;Peter J. Brown.
Proceedings of the National Academy of Sciences of the United States of America (1997)

2553 Citations

Roles of PPARs in health and disease.

Sander Kersten;Béatrice Desvergne;Walter Wahli.
Nature (2000)

2340 Citations

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

Sander Kersten;Josiane Seydoux;Jeffrey M. Peters;Frank J. Gonzalez.
Journal of Clinical Investigation (1999)

1825 Citations

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

Christine Dreyer;Grigorios Krey;Hansjörg Keller;Francoise Givel.
Cell (1992)

1712 Citations

The PPARalpha-leukotriene B4 pathway to inflammation control.

Pallavi R. Devchand;Hansjörg Keller;Jeffrey Maurice Peters;Manuel Vazquez.
Nature (1996)

1668 Citations

Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

Grigorios Krey;Olivier Braissant;Fabienne L’Horset;Eric Kalkhoven.
Molecular Endocrinology (1997)

1380 Citations

International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

Liliane Michalik;Johan Auwerx;Joel P. Berger;V. Krishna Chatterjee.
Pharmacological Reviews (2006)

1095 Citations

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

Hansjorg Keller;Christine Dreyer;Jeffrey Medin;Abderrahim Mahfoudi.
Proceedings of the National Academy of Sciences of the United States of America (1993)

1085 Citations

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