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Genetics
Switzerland
2026
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Genetics and Molecular Biology
Singapore
2024

D-Index & Metrics

Genetics

D-Index
122
Citations
68684
World Ranking
344
National Ranking
7

Research.com Recognitions

  • 2026 - Research.com Genetics in Switzerland Leader Award
  • 2025 - Research.com Genetics in Switzerland Leader Award
  • 2024 - Research.com Genetics in Switzerland Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Singapore Leader Award
  • 2023 - Research.com Genetics in Switzerland Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Singapore Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Walter Wahli is affiliated with the University of Lausanne in Switzerland. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a distinguished focus on Molecular Biology, Physiology, Epidemiology, Surgery, and Rheumatology.

Their scholarly output includes a strong emphasis on liver disease diagnosis and treatment, peroxisome proliferator-activated receptors (PPARs), adipose tissue and metabolism, metabolism related to diabetes and cancer, pancreatic function and diabetes, GDF15 and related biomarkers, as well as nutrition and health in aging.

Recent papers authored by Wahli cover a range of topics connected to metabolic and liver diseases. These include:

  • "Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants," 2020, Biomolecules
  • "Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease," 2020, Cells
  • "Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity," 2020, Scientific Reports
  • "GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK," 2021, Cell Reports
  • "Role of Dietary Supplements and Probiotics in Modulating Microbiota and Bone Health: The Gut-Bone Axis," 2022, Cells

Among frequent collaborators in Wahli's body of work are Manuel Vázquez-Carrera, Hervé Guillou, Alexandra Montagner, Anne Fougerat, and Arnaud Polizzi. These coauthors have contributed extensively to publications alongside Wahli.

Wahli has published multiple works in several recurring scientific journals. The primary publication venues include Cells, International Journal of Molecular Sciences, bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, and Cancers.

The scientist's expertise covers broad topics in metabolic health and molecular mechanisms affecting liver and adipose tissue functions. These areas contribute to understanding diseases such as non-alcoholic fatty liver disease (NAFLD), as well as the role of PPARs and metabolic biomarkers such as GDF15 in disease processes.

Walter Wahli has been recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Peroxisome proliferator-activated receptors: nuclear control of metabolism.

    Béatrice Desvergne;Walter Wahli

  • Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

    O Braissant;F Foufelle;C Scotto;M Dauça

  • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

    Steven A. Kliewer;Scott S. Sundseth;Stacey A. Jones;Peter J. Brown

  • Roles of PPARs in health and disease.

    Sander Kersten;Béatrice Desvergne;Walter Wahli

  • Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

    Sander Kersten;Josiane Seydoux;Jeffrey M. Peters;Frank J. Gonzalez

  • CONTROL OF THE PEROXISOMAL BETA- OXIDATION PATHWAY BY A NOVEL FAMILY OF NUCLEAR HORMONE RECEPTORS

    Christine Dreyer;Grigorios Krey;Hansjörg Keller;Francoise Givel

  • The PPARalpha-leukotriene B4 pathway to inflammation control.

    Pallavi R. Devchand;Hansjörg Keller;Jeffrey Maurice Peters;Manuel Vazquez

  • Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

    Grigorios Krey;Olivier Braissant;Fabienne L’Horset;Eric Kalkhoven

  • International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

    Liliane Michalik;Johan Auwerx;Joel P. Berger;V. Krishna Chatterjee

  • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

    Hansjorg Keller;Christine Dreyer;Jeffrey Medin;Abderrahim Mahfoudi

  • A unified nomenclature system for the nuclear receptor superfamily

    J. Auwerx;E. Baulieu;M. Beato;M. Becker-Andre

  • Transcriptional Regulation of Metabolism

    Béatrice Desvergne;Liliane Michalik;Walter Wahli

  • PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS: A Nuclear Receptor Signaling Pathway in Lipid Physiology

    Thomas Lemberger;Béatrice Desvergne;Walter Wahli

  • From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions

    Jérôme N. Feige;Laurent Gelman;Liliane Michalik;Béatrice Desvergne

  • Peroxisome-proliferator-activated receptors and cancers: complex stories.

    Liliane Michalik;Béatrice Desvergne;Walter Wahli

  • PPARs at the crossroads of lipid signaling and inflammation

    Walter Wahli;Liliane Michalik

  • A high-efficiency HeLa cell nuclear transcription extract.

    David J. Shapiro;Phillip A. Sharp;Walter W. Wahli;Martha J. Keller

  • Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies.

    Pierre Desreumaux;Laurent Dubuquoy;Sophie Nutten;Michel Peuchmaur

  • Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene

    Sander Kersten;Stéphane Mandard;Nguan Soon Tan;Pascal Escher

  • Peroxisome proliferator-activated receptors: insight into multiple cellular functions

    Pascal Escher;Walter Wahli

Frequent Co-Authors

Béatrice Desvergne
Béatrice Desvergne University of Lausanne
Liliane Michalik
Liliane Michalik University of Lausanne
Nguan Soon Tan
Nguan Soon Tan Nanyang Technological University
Hervé Guillou
Hervé Guillou INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Manuel Vázquez-Carrera
Manuel Vázquez-Carrera University of Barcelona
Sander Kersten
Sander Kersten Wageningen University & Research
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
Catherine Postic
Catherine Postic Institut Cochin
Gerhart U. Ryffel
Gerhart U. Ryffel University of Duisburg-Essen

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