World's Best Scientists 2026 revealed!
Jean-Charles Fruchart

Jean-Charles Fruchart

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Medicine
France
2023

D-Index & Metrics

Medicine

D-Index
147
Citations
80827
World Ranking
1285
National Ranking
29

Jean-Charles Fruchart publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Jean-Charles Fruchart sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 804 publications — 87th percentile

87% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Jean-Charles Fruchart D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Jean-Charles Fruchart sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 147 D-Index — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

  • 2023 - Research.com Medicine in France Leader Award

Overview

Jean-Charles Fruchart is affiliated with the Institut Pasteur in France and has contributed extensively to research in medicine, particularly focusing on the areas of metabolism and cardiovascular health. Their work spans several subfields including molecular biology, endocrinology, diabetes and metabolism, surgery, epidemiology, and cardiology.

The primary topics of Jean-Charles Fruchart's research involve peroxisome proliferator-activated receptors, liver disease diagnosis and treatment, diabetes treatment and management, as well as diabetes-related cardiovascular risks and lipoproteins. Their investigations also cover fatty acid research and health, cholesterol and lipid metabolism, and endoplasmic reticulum stress and its role in disease.

Key recent publications by Jean-Charles Fruchart include:

  • Lessons from PROMINENT and prospects for pemafibrate, 2024, Cardiovascular Diabetology
  • Selective PPARα Modulator Pemafibrate and Sodium-Glucose Cotransporter 2 Inhibitor Tofogliflozin Combination Treatment Improved Histopathology in Experimental Mice Model of Non-Alcoholic Steatohepatitis, 2022, Cells
  • Selective Peroxisome Proliferator-Activated Receptor Alpha Modulators (SPPARMα) in the Metabolic Syndrome: Is Pemafibrate Light at the End of the Tunnel?, 2021, Current Atherosclerosis Reports
  • Selective Peroxisome Proliferator-Activated Receptor Alpha Modulators (SPPARMα): New Opportunities to Reduce Residual Cardiovascular Risk in Chronic Kidney Disease?, 2020, Current Atherosclerosis Reports

Another notable paper co-authored by Jean-Charles Fruchart is Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk, published in 2022 in the New England Journal of Medicine.

Jean-Charles Fruchart collaborates frequently with several researchers, including Tatsuhiko Kodama, Jamila Fruchart-Najib, Michel P. Hermans, Koutaro Yokote, and Peter Libby. These collaborations reflect a consistent engagement within a network of experts focused on related biomedical topics.

The scientist's research outputs are published across journals frequently including Current Atherosclerosis Reports, New England Journal of Medicine, Cells, and Cardiovascular Diabetology. This range illustrates a focus on cardiovascular and metabolic disorders at both clinical and molecular levels.

Best Publications

  • Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism

    Bart Staels;Jean Dallongeville;Johan Auwerx;Kristina Schoonjans

  • HDL Cholesterol, Very Low Levels of LDL Cholesterol, and Cardiovascular Events

    Philip Barter;Antonio M. Gotto;John C. LaRosa;Jaman Maroni

  • The organization, promoter analysis, and expression of the human PPARgamma gene.

    Lluis Fajas;Didier Auboeuf;Eric Raspé;Kristina Schoonjans

  • Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators

    Bart Staels;Wolfgang Koenig;Aïda Habib;Régine Merval

  • PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.

    Chinetti G;Lestavel S;Bocher;Remaley At

  • Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

    Philippe Delerive;Karolien De Bosscher;Sandrine Besnard;Wim Vanden Berghe

  • An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing

    Len A. Pennacchio;Michael Olivier;Jaroslav A. Hubacek;Jonathan C. Cohen

  • Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages.

    Giulia Chinetti;Sabine Griglio;Micheline Antonucci;Inés Pineda Torra

  • Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity

    Robert Ross;Ian J. Neeland;Shizuya Yamashita;Iris Shai

  • Sorting out the roles of PPARα in energy metabolism and vascular homeostasis

    Philippe Lefebvre;Giulia Chinetti;Jean-Charles Fruchart;Bart Staels

  • Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

    Ian J. Neeland;Robert Ross;Jean Pierre Després;Yuji Matsuzawa

  • Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity

    Michèle Guerre-Millo;Philippe Gervois;Eric Raspé;Lise Madsen

  • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice.

    Anne-Marie Lefebvre;Inhua Chen;Pierre Desreumaux;Jamila Najib

  • Therapeutic Roles of Peroxisome Proliferator–Activated Receptor Agonists

    Bart Staels;Jean Charles Fruchart

  • Peroxisome proliferator-activated receptors in inflammation control.

    P Delerive;JC Fruchart;B Staels

  • Measurement of Arterial Wall Thickness as a Surrogate Marker for Atherosclerosis

    Eric de Groot;G. Kees Hovingh;Albert Wiegman;Patrick Duriez

  • Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway

    Philippe Delerive;Françoise Martin-Nizard;Giulia Chinetti;François Trottein

  • Effect of lowering LDL cholesterol substantially below currently recommended levels in patients with coronary heart disease and diabetes: the Treating to New Targets (TNT) study.

    James Shepherd;Philip Barter;Rafael Carmena;Prakash Deedwania

  • Intensive Lipid Lowering With Atorvastatin in Patients With Stable Coronary Disease

    J.C. LaRosa;S.M. Grundy;D.D. Waters

  • Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation

    Virginie Bocher;Giulia Chinetti;Jean-Charles Fruchart;Bart Staels

Frequent Co-Authors

Bart Staels
Bart Staels University of Lille
Catherine Fievet
Catherine Fievet Institut Pasteur
Jean Dallongeville
Jean Dallongeville Institut Pasteur
Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
Gérard Torpier
Gérard Torpier Institut Pasteur
Folkert Kuipers
Folkert Kuipers University Medical Center Groningen
Len A. Pennacchio
Len A. Pennacchio Lawrence Berkeley National Laboratory
Bertrand Cariou
Bertrand Cariou University of Nantes
Roméo Cecchelli
Roméo Cecchelli Artois University
Dominique Arveiler
Dominique Arveiler University of Strasbourg

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