Folkert Kuipers spends much of his time researching Internal medicine, Endocrinology, Cholesterol, Liver X receptor and Bile acid. His Internal medicine study focuses mostly on High-density lipoprotein, Lipoprotein, Cholesterol 7 alpha-hydroxylase, Very low-density lipoprotein and Lipid metabolism. His research in Endocrinology intersects with topics in Farnesoid X receptor and ABCA1.
His Cholesterol study combines topics from a wide range of disciplines, such as Intestinal absorption, Apolipoprotein E and HMG-CoA reductase. His work focuses on many connections between Liver X receptor and other disciplines, such as Sitosterolemia, that overlap with his field of interest in ABCG5 and ABCG8. His study with Bile acid involves better knowledge in Biochemistry.
Folkert Kuipers mainly investigates Internal medicine, Endocrinology, Cholesterol, Biochemistry and Bile acid. His Secretion, Cholestasis, Insulin, Insulin resistance and Lipoprotein investigations are all subjects of Internal medicine research. His studies link Liver X receptor with Endocrinology.
He has researched Cholesterol in several fields, including Phospholipid, ABCA1 and Excretion. Folkert Kuipers works mostly in the field of Bile acid, limiting it down to topics relating to Farnesoid X receptor and, in certain cases, G protein-coupled bile acid receptor, as a part of the same area of interest. Folkert Kuipers interconnects Apolipoprotein E, Lipogenesis, Steatosis and Apolipoprotein B in the investigation of issues within Very low-density lipoprotein.
Folkert Kuipers mostly deals with Internal medicine, Endocrinology, Cholesterol, Bile acid and Liver X receptor. As part of one scientific family, Folkert Kuipers deals mainly with the area of Internal medicine, narrowing it down to issues related to the Nuclear receptor, and often Pharmacology. His research brings together the fields of Farnesoid X receptor and Endocrinology.
His Farnesoid X receptor research is multidisciplinary, relying on both G protein-coupled bile acid receptor, Receptor, Enterohepatic circulation and Cell biology. The concepts of his Bile acid study are interwoven with issues in Liver disease and Very low-density lipoprotein. In Liver X receptor, Folkert Kuipers works on issues like Lipogenesis, which are connected to Fatty acid synthesis and Carbohydrate-responsive element-binding protein.
His scientific interests lie mostly in Internal medicine, Endocrinology, Cholesterol, Liver X receptor and Farnesoid X receptor. His Internal medicine study typically links adjacent topics like Nuclear receptor. His research related to Bile acid, Reverse cholesterol transport, Cholesterol 7 alpha-hydroxylase, Insulin resistance and Insulin might be considered part of Endocrinology.
His Cholesterol research incorporates elements of Secretion and Biliary tract. His research integrates issues of Liver X receptor alpha, DNA methylation, ABCA1, Promoter and Apolipoprotein E in his study of Liver X receptor. His study focuses on the intersection of Farnesoid X receptor and fields such as G protein-coupled bile acid receptor with connections in the field of Adipocyte, Wnt signaling pathway, Cellular differentiation and Peroxisome proliferator-activated receptor.
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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
Philippe Lefebvre;Bertrand Cariou;Fleur Lien;Folkert Kuipers.
Physiological Reviews (2009)
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
Johan W. Jonker;Marije Buitelaar;Els Wagenaar;Martin A. van der Valk.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.
Liam R. Brunham;Janine K. Kruit;Jahangir Iqbal;Catherine Fievet.
Journal of Clinical Investigation (2006)
Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles
Aldo Grefhorst;Baukje M Elzinga;Peter J Voshol;Torsten Plösch.
Journal of Biological Chemistry (2002)
The Farnesoid X Receptor Modulates Adiposity and Peripheral Insulin Sensitivity in Mice
Bertrand Cariou;Bertrand Cariou;Bertrand Cariou;Kirsten Van Harmelen;Kirsten Van Harmelen;Kirsten Van Harmelen;Daniel Duran-Sandoval;Daniel Duran-Sandoval;Daniel Duran-Sandoval;Theo H. Van Dijk.
Journal of Biological Chemistry (2006)
The Farnesoid X Receptor A Molecular Link Between Bile Acid and Lipid and Glucose Metabolism
Thierry Claudel;Bart Staels;Folkert Kuipers.
Arteriosclerosis, Thrombosis, and Vascular Biology (2005)
The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity
Stéphane Mandard;Fokko Zandbergen;Esther van Straten;Walter Wahli.
Journal of Biological Chemistry (2006)
Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.
Ronald P.J. Oude Elferink;Dirk K.F. Meijer;Folkert Kuipers;Peter L.M. Jansen.
Biochimica et Biophysica Acta (1995)
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.
Plm Jansen;SS Strautnieks;E Jacquemin;M Hadchouel.
Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.
Thierry Claudel;Ekkehard Sturm;Hélène Duez;Inés Pineda Torra.
Journal of Clinical Investigation (2002)
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