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D-Index
105
Citations
36996
World Ranking
6814
National Ranking
260

Overview

Folkert Kuipers is affiliated with the University Medical Center Groningen in the Netherlands. Their research predominantly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these broad areas, their work frequently intersects subfields including Surgery, Oncology, Molecular Biology, Epidemiology, and Physiology.

Their work covers various important topics such as Drug Transport and Resistance Mechanisms, Liver Disease Diagnosis and Treatment, Pediatric Hepatobiliary Diseases and Treatments, Gut Microbiota and Health, Cholesterol and Lipid Metabolism, Diet and Metabolism Studies, and Metabolomics and Mass Spectrometry Studies.

Several recent papers illustrate the scientific interests and contributions of Kuipers. These include:

  • Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome (2022, Nature Medicine)
  • Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity (2020, Nature Communications)
  • Gut microbiome and bile acids in obesity-related diseases (2021, Best Practice & Research Clinical Endocrinology & Metabolism)
  • Role of bile acids in inflammatory liver diseases (2021, Seminars in Immunopathology)
  • Genetic and Microbial Associations to Plasma and Fecal Bile Acids in Obesity Relate to Plasma Lipids and Liver Fat Content (2020, Cell Reports)

Frequent co-authors of Kuipers include:

  • Martijn Koehorst
  • Vincent W. Bloks
  • Jan Freark de Boer
  • Henkjan J. Verkade
  • Jingyuan Fu

Kuipers has published multiple articles in several key scientific venues. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Atherosclerosis
  • Nature Communications
  • Molecular Metabolism
  • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Best Publications

  • Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

    Philippe Lefebvre;Bertrand Cariou;Fleur Lien;Folkert Kuipers

  • The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

    Johan W. Jonker;Marije Buitelaar;Els Wagenaar;Martin A. van der Valk

  • Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

    Allyson K. Palmer;Ming Xu;Ming Xu;Yi Zhu;Tamar Pirtskhalava

  • Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.

    Liam R. Brunham;Janine K. Kruit;Jahangir Iqbal;Catherine Fievet

  • The Farnesoid X Receptor Modulates Adiposity and Peripheral Insulin Sensitivity in Mice

    Bertrand Cariou;Bertrand Cariou;Bertrand Cariou;Kirsten Van Harmelen;Kirsten Van Harmelen;Kirsten Van Harmelen;Daniel Duran-Sandoval;Daniel Duran-Sandoval;Daniel Duran-Sandoval;Theo H. Van Dijk

  • Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

    Aldo Grefhorst;Baukje M Elzinga;Peter J Voshol;Torsten Plösch

  • The Farnesoid X Receptor A Molecular Link Between Bile Acid and Lipid and Glucose Metabolism

    Thierry Claudel;Bart Staels;Folkert Kuipers

  • The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity

    Stéphane Mandard;Fokko Zandbergen;Esther van Straten;Walter Wahli

  • Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.

    Ronald P.J. Oude Elferink;Dirk K.F. Meijer;Folkert Kuipers;Peter L.M. Jansen

  • Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.

    Plm Jansen;SS Strautnieks;E Jacquemin;M Hadchouel

  • Beyond intestinal soap—bile acids in metabolic control

    Folkert Kuipers;Vincent W. Bloks;Albert K. Groen

  • Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.

    Thierry Claudel;Ekkehard Sturm;Hélène Duez;Inés Pineda Torra

  • A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis.

    Eelke Brandsma;Niels J. Kloosterhuis;Mirjam Koster;Mirjam Koster;Daphne C. Dekker

  • Regulatory enzymes of mitochondrial beta-oxidation as targets for treatment of the metabolic syndrome

    M. Schreurs;F. Kuipers;F. R. van der Leij

  • Hepatic Steatosis: A Mediator of the Metabolic Syndrome: Lessons From Animal Models

    M. den Boer;P.J. Voshol;F. Kuipers;L.M. Havekes

  • Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity

    Johannes M. Aerts;Roelof Ottenhoff;Andrew S. Powlson;Aldo Grefhorst

  • Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity

    Janne Prawitt;Mouaadh Abdelkarim;Johanna H.M. Stroeve;Iuliana Popescu

  • Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion.

    Han Roelofsen;Henk Wolters;Marja J.A. Van Luyn;Naoyuki Miura

  • The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity (vol 281, pg 934, 2006)

    Stephane Mandard;Fokko Zandbergen;Esther van Straten;Walter Wahli

  • Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles Chapter 3

    Aldo Grefhorst;Baukje M. Elzinga;Peter J. Voshol;Torsten Plösch

Frequent Co-Authors

Albert K. Groen
Albert K. Groen University of Amsterdam
Bart Staels
Bart Staels University of Lille
Michael Müller
Michael Müller University of East Anglia
Johannes A. Romijn
Johannes A. Romijn University of Amsterdam
Louis M. Havekes
Louis M. Havekes Leiden University Medical Center
Bertrand Cariou
Bertrand Cariou University of Nantes
Peter L.M. Jansen
Peter L.M. Jansen Maastricht University
Ronald P.J. Oude Elferink
Ronald P.J. Oude Elferink University of Amsterdam
Jingyuan Fu
Jingyuan Fu University Medical Center Groningen
Hans M.G. Princen
Hans M.G. Princen Netherlands Organisation for Applied Scientific Research

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