D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 96 Citations 30,978 659 World Ranking 5903 National Ranking 204

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Enzyme
  • Gene

Folkert Kuipers spends much of his time researching Internal medicine, Endocrinology, Cholesterol, Liver X receptor and Bile acid. His Internal medicine study focuses mostly on High-density lipoprotein, Lipoprotein, Cholesterol 7 alpha-hydroxylase, Very low-density lipoprotein and Lipid metabolism. His research in Endocrinology intersects with topics in Farnesoid X receptor and ABCA1.

His Cholesterol study combines topics from a wide range of disciplines, such as Intestinal absorption, Apolipoprotein E and HMG-CoA reductase. His work focuses on many connections between Liver X receptor and other disciplines, such as Sitosterolemia, that overlap with his field of interest in ABCG5 and ABCG8. His study with Bile acid involves better knowledge in Biochemistry.

His most cited work include:

  • Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation (1060 citations)
  • The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria (674 citations)
  • Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles (428 citations)

What are the main themes of his work throughout his whole career to date?

Folkert Kuipers mainly investigates Internal medicine, Endocrinology, Cholesterol, Biochemistry and Bile acid. His Secretion, Cholestasis, Insulin, Insulin resistance and Lipoprotein investigations are all subjects of Internal medicine research. His studies link Liver X receptor with Endocrinology.

He has researched Cholesterol in several fields, including Phospholipid, ABCA1 and Excretion. Folkert Kuipers works mostly in the field of Bile acid, limiting it down to topics relating to Farnesoid X receptor and, in certain cases, G protein-coupled bile acid receptor, as a part of the same area of interest. Folkert Kuipers interconnects Apolipoprotein E, Lipogenesis, Steatosis and Apolipoprotein B in the investigation of issues within Very low-density lipoprotein.

He most often published in these fields:

  • Internal medicine (69.49%)
  • Endocrinology (65.92%)
  • Cholesterol (25.15%)

What were the highlights of his more recent work (between 2008-2021)?

  • Internal medicine (69.49%)
  • Endocrinology (65.92%)
  • Cholesterol (25.15%)

In recent papers he was focusing on the following fields of study:

Folkert Kuipers mostly deals with Internal medicine, Endocrinology, Cholesterol, Bile acid and Liver X receptor. As part of one scientific family, Folkert Kuipers deals mainly with the area of Internal medicine, narrowing it down to issues related to the Nuclear receptor, and often Pharmacology. His research brings together the fields of Farnesoid X receptor and Endocrinology.

His Farnesoid X receptor research is multidisciplinary, relying on both G protein-coupled bile acid receptor, Receptor, Enterohepatic circulation and Cell biology. The concepts of his Bile acid study are interwoven with issues in Liver disease and Very low-density lipoprotein. In Liver X receptor, Folkert Kuipers works on issues like Lipogenesis, which are connected to Fatty acid synthesis and Carbohydrate-responsive element-binding protein.

Between 2008 and 2021, his most popular works were:

  • Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation (1060 citations)
  • Beyond intestinal soap—bile acids in metabolic control (248 citations)
  • Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity (191 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

His scientific interests lie mostly in Internal medicine, Endocrinology, Cholesterol, Liver X receptor and Farnesoid X receptor. His Internal medicine study typically links adjacent topics like Nuclear receptor. His research related to Bile acid, Reverse cholesterol transport, Cholesterol 7 alpha-hydroxylase, Insulin resistance and Insulin might be considered part of Endocrinology.

His Cholesterol research incorporates elements of Secretion and Biliary tract. His research integrates issues of Liver X receptor alpha, DNA methylation, ABCA1, Promoter and Apolipoprotein E in his study of Liver X receptor. His study focuses on the intersection of Farnesoid X receptor and fields such as G protein-coupled bile acid receptor with connections in the field of Adipocyte, Wnt signaling pathway, Cellular differentiation and Peroxisome proliferator-activated receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

Philippe Lefebvre;Bertrand Cariou;Fleur Lien;Folkert Kuipers.
Physiological Reviews (2009)

1582 Citations

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

Johan W. Jonker;Marije Buitelaar;Els Wagenaar;Martin A. van der Valk.
Proceedings of the National Academy of Sciences of the United States of America (2002)

956 Citations

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.

Liam R. Brunham;Janine K. Kruit;Jahangir Iqbal;Catherine Fievet.
Journal of Clinical Investigation (2006)

597 Citations

Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

Aldo Grefhorst;Baukje M Elzinga;Peter J Voshol;Torsten Plösch.
Journal of Biological Chemistry (2002)

569 Citations

The Farnesoid X Receptor Modulates Adiposity and Peripheral Insulin Sensitivity in Mice

Bertrand Cariou;Bertrand Cariou;Bertrand Cariou;Kirsten Van Harmelen;Kirsten Van Harmelen;Kirsten Van Harmelen;Daniel Duran-Sandoval;Daniel Duran-Sandoval;Daniel Duran-Sandoval;Theo H. Van Dijk.
Journal of Biological Chemistry (2006)

567 Citations

The Farnesoid X Receptor A Molecular Link Between Bile Acid and Lipid and Glucose Metabolism

Thierry Claudel;Bart Staels;Folkert Kuipers.
Arteriosclerosis, Thrombosis, and Vascular Biology (2005)

513 Citations

The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity

Stéphane Mandard;Fokko Zandbergen;Esther van Straten;Walter Wahli.
Journal of Biological Chemistry (2006)

491 Citations

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.

Ronald P.J. Oude Elferink;Dirk K.F. Meijer;Folkert Kuipers;Peter L.M. Jansen.
Biochimica et Biophysica Acta (1995)

489 Citations

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.

Plm Jansen;SS Strautnieks;E Jacquemin;M Hadchouel.
Gastroenterology (1999)

471 Citations

Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.

Thierry Claudel;Ekkehard Sturm;Hélène Duez;Inés Pineda Torra.
Journal of Clinical Investigation (2002)

419 Citations

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