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Theo J.C. Van Berkel

Theo J.C. Van Berkel

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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
30686
World Ranking
2316
National Ranking
56

Medicine

D-Index
91
Citations
30981
World Ranking
11733
National Ranking
450

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Theo J.C. Van Berkel is affiliated with Leiden University in the Netherlands. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a focus on diseases and mechanisms related to cardiovascular health and metabolism.

The main fields of study for Van Berkel include Medicine and Biochemistry, Genetics and Molecular Biology. Their work is further specialized in subfields such as Molecular Biology, Surgery, Immunology, Oncology, and Endocrinology, Diabetes, and Metabolism.

The primary research topics covered by Van Berkel comprise:

  • Atherosclerosis and Cardiovascular Diseases
  • Chemokine receptors and signaling
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cancer, Lipids, and Metabolism
  • Cholesterol and Lipid Metabolism
  • RNA Interference and Gene Delivery
  • RNA and protein synthesis mechanisms

Van Berkel has contributed significantly to the scientific literature, with notable recent papers including:

  • "N-Acetyl Galactosamine Targeting: Paving the Way for Clinical Application of Nucleotide Medicines in Cardiovascular Diseases," 2021, Arteriosclerosis Thrombosis and Vascular Biology
  • "Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis," 2022, Cardiovascular Research
  • "CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization," 2024, Frontiers in Immunology
  • "Disruption of Phospholipid Transfer Protein-Mediated High-Density Lipoprotein Maturation Reduces Scavenger Receptor BI Deficiency-Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications," 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • "Impact of bone marrow ATP-binding cassette transporter A1 deficiency on atherogenesis is independent of the presence of the low-density lipoprotein receptor," 2021, Atherosclerosis

Frequent co-authors in Van Berkel's research include:

  • Erik A.L. Biessen
  • Ilze Bot
  • Menno Hoekstra
  • Miranda Van Eck
  • Marijke M. Westra

Their work has been published multiple times in key scientific journals such as:

  • Arteriosclerosis Thrombosis and Vascular Biology
  • Cardiovascular Research
  • Frontiers in Immunology
  • Atherosclerosis
  • European Journal of Immunology

Best Publications

  • A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

    Hiroshi Suzuki;Hiroshi Suzuki;Yukiko Kurihara;Motohiro Takeya;Nobuo Kamada

  • Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

    Jayaprakash K. Nair;Jennifer L. S. Willoughby;Amy Chan;Klaus Charisse

  • Receptors, Mediators, and Mechanisms Involved in Bacterial Sepsis and Septic Shock

    Edwin S. Van Amersfoort;Theo J. C. Van Berkel;Johan Kuiper

  • The influence of cytokines on the integrity of the blood-brain barrier in vitro

    Helga E. de Vries;Margret C.M. Blom-Roosemalen;Marijke van Oosten;Albert G. de Boer

  • The Blood-Brain Barrier in Neuroinflammatory Diseases

    Helga E. de Vries;Johan Kuiper;Albertus G. de Boer;Theo J. C. Van Berkel

  • Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues

    Miranda Van Eck;I. Sophie T. Bos;Wolfgang E. Kaminski;Evelyn Orsó

  • Endothelial KLF2 Links Local Arterial Shear Stress Levels to the Expression of Vascular Tone-Regulating Genes

    Rob J. Dekker;Johannes V. van Thienen;Jakub Rohlena;Saskia C. de Jager

  • Perivascular Mast Cells Promote Atherogenesis and Induce Plaque Destabilization in Apolipoprotein E–Deficient Mice

    Ilize Bot;Saskia C. A. De Jager;Aima Zernecke;Ken A. Lindstedt

  • Liver Kupffer cells rapidly remove red blood cell–derived vesicles from the circulation by scavenger receptors

    Frans L. A. Willekens;Jan M. Werre;J. Kar Kruijt;Bregt Roerdinkholder-Stoelwinder

  • Genetic Variant of the Scavenger Receptor BI in Humans

    Menno Vergeer;Suzanne J A Korporaal;Remco Franssen;Illiana Meurs

  • Induction of Rapid Atherogenesis by Perivascular Carotid Collar Placement in Apolipoprotein E–Deficient and Low-Density Lipoprotein Receptor–Deficient Mice

    Jan H. von der Thüsen;Theo J.C. van Berkel;Erik A.L. Biessen

  • Interleukins in Atherosclerosis: Molecular Pathways and Therapeutic Potential

    Jan H. Von der Thüsen;Johan Kuiper;Theo J. C. Van Berkel;Erik A. L. Biessen

  • FTY720, a Synthetic Sphingosine 1 Phosphate Analogue, Inhibits Development of Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

    Jerzy-Roch Nofer;Martine Bot;Martin Brodde;Paul J. Taylor

  • Differential Effects of Scavenger Receptor BI Deficiency on Lipid Metabolism in Cells of the Arterial Wall and in the Liver

    Miranda Van Eck;Jaap Twisk;Menno Hoekstra;Brechje T. Van Rij

  • Induction of Atherosclerotic Plaque Rupture in Apolipoprotein E−/− Mice After Adenovirus-Mediated Transfer of p53

    Jan H. Von Der Thüsen;Bart J. M. Van Vlijmen;Rob C. Hoeben;Mark M. Kockx

  • Recombinant lipoproteins: lipoprotein-like lipid particles for drug targeting.

    Patrick C.N Rensen;Remco L.A de Vrueh;Johan Kuiper;Martin K Bijsterbosch

  • Macrophage ABCG1 Deletion Disrupts Lipid Homeostasis in Alveolar Macrophages and Moderately Influences Atherosclerotic Lesion Development in LDL Receptor-Deficient Mice

    Ruud Out;Menno Hoekstra;Reeni B. Hildebrand;Janine K. Kruit

  • The peripheral blood mononuclear cell microRNA signature of coronary artery disease

    Menno Hoekstra;Christian A.C. van der Lans;Bente Halvorsen;Lars Gullestad

  • Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells.

    Menno Hoekstra;J.Kar Kruijt;Miranda Van Eck;Theo J.C. van Berkel

  • Receptors, Mediators, and Mechanisms Involved in Bacterial Sepsis and Septic Shock

    Edwin S. Van Amersfoort;Theo J. C. Van Berkel;Johan Kuiper

Frequent Co-Authors

Erik A.L. Biessen
Erik A.L. Biessen Maastricht University
Johan Kuiper
Johan Kuiper Leiden University
Patrick C. N. Rensen
Patrick C. N. Rensen Leiden University Medical Center
Louis M. Havekes
Louis M. Havekes Leiden University Medical Center
Muthiah Manoharan
Muthiah Manoharan Alnylam Pharmaceuticals (United States)
Paul H.A. Quax
Paul H.A. Quax Leiden University Medical Center
Domenico Praticò
Domenico Praticò Temple University
Ko Willems van Dijk
Ko Willems van Dijk Leiden University Medical Center
Christian Weber
Christian Weber Ludwig-Maximilians-Universität München
Peter A. C. 't Hoen
Peter A. C. 't Hoen Radboud University

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