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Medicine

D-Index
104
Citations
49897
World Ranking
6950
National Ranking
75

Overview

Petri T. Kovanen is affiliated with the Wihuri Research Institute in Finland and has a research portfolio primarily focused on medicine. Their work spans a broad range of topics within this field, with particular attention to surgery, immunology, cancer research, molecular biology, and endocrinology, diabetes, and metabolism.

The scientist's research interests include several main topics, notably:

  • Lipoproteins and Cardiovascular Health
  • Atherosclerosis and Cardiovascular Diseases
  • Cancer, Lipids, and Metabolism
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • COVID-19 Clinical Research Studies
  • Inflammasome and Immune Disorders
  • Cholesterol and Lipid Metabolism

Their publication record demonstrates a significant presence in scientific journals related to cardiovascular and internal medicine. Frequent publication venues include:

  • Atherosclerosis
  • Frontiers in Cardiovascular Medicine
  • Journal of Internal Medicine
  • Journal of Clinical Lipidology
  • Annals of Medicine

Petri T. Kovanen has collaborated extensively with several researchers. Frequent co-authors are:

  • Alpo Vuorio
  • Frederick J. Raal
  • Katariina Öörni
  • Matti Jauhiainen
  • Miriam Lee-Rueckert

Examples of recent papers associated with topics related to immune cells, cardiovascular health, and metabolism include:

  • "Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts," 2020, Theranostics
  • "Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease," 2020, JCI Insight
  • "Mast cells and complement system: Ancient interactions between components of innate immunity," 2020, Allergy
  • "Cardiac Mast Cells: Underappreciated Immune Cells in Cardiovascular Homeostasis and Disease," 2020, Trends in Immunology
  • "Cyclodextrins: Potential therapeutics against atherosclerosis," 2020, Pharmacology & Therapeutics

These publications indicate involvement in interdisciplinary research connecting immunology, lipid metabolism, and cardiovascular conditions. The overlap of research in innate immunity and metabolic diseases is apparent.

Best Publications

  • Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society

    Borge G. Nordestgaard;M. John Chapman;Steve E. Humphries;Henry N. Ginsberg

  • Lipoprotein(a) as a cardiovascular risk factor: current status

    Børge G. Nordestgaard;M. John Chapman;Kausik Ray;Jan Borén

  • Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

    M John Chapman;Henry N Ginsberg;Pierre Amarenco;Felicita Andreotti

  • Regulation of plasma cholesterol by lipoprotein receptors

    Michael S. Brown;Petri T. Kovanen;Joseph L. Goldstein

  • Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

    Marina Cuchel;Eric Bruckert;Henry N. Ginsberg;Frederick J. Raal

  • Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

    Kristiina Rajamäki;Jani Lappalainen;Katariina Öörni;Elina Välimäki

  • Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

    Magnus Bäck;Arif Yurdagul;Ira Tabas;Katariina Öörni

  • Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability.

    Bernhard Schieffer;Elisabeth Schieffer;Denise Hilfiker-Kleiner;Andres Hilfiker

  • Familial Hypercholesterolaemia in Children and Adolescents: Gaining Decades of Life by Optimizing Detection and Treatment

    Albert Wiegman;Samuel S. Gidding;Gerald F Watts;M John Chapman

  • Infiltrates of Activated Mast Cells at the Site of Coronary Atheromatous Erosion or Rupture in Myocardial Infarction

    Petri T. Kovanen;Maija Kaartinen;Timo Paavonen

  • Homozigot ailevi hiperkolesterolemi: klinisyenlerin tanıyı ve klinik yönetimi geliştirmelerine yönelik yeni anlayışlar ve rehberlik. Avrupa Ateroskleroz Derneği’nin Ailevi Hiperkolesterolemi Üzerine Uzlaşı Paneli yazılı görüşü

    Marina Cuchel;Eric Bruckert;Henry N. Ginsberg;Frederick J. Raal

  • Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture.

    Maija Kaartinen;Antti Penttila;Petri T. Kovanen

  • The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E.

    E. E T Windler;P. T. Kovanen;Y. S. Chao;Michael S Brown

  • The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

    Robert A. Hegele;Henry N. Ginsberg;M. John Chapman;Børge G. Nordestgaard

  • Structure of low density lipoprotein (LDL) particles: basis for understanding molecular changes in modified LDL.

    Tiia Hevonoja;Markku O Pentikäinen;Marja T Hyvönen;Petri T Kovanen

  • Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease

    Helena Gylling;Jogchum Plat;Stephen Turley;Henry N. Ginsberg

  • Human mast cell chymase and leukocyte elastase release latent transforming growth factor-beta 1 from the extracellular matrix of cultured human epithelial and endothelial cells.

    Jussi Taipale;Jouko Lohi;Juhani Saarinen;Petri T. Kovanen

  • Association Between Myocardial Infarction and the Mast Cells in the Adventitia of the Infarct-Related Coronary Artery

    Petri Laine;Maija Kaartinen;Antti Penttilä;Pertti Panula

  • Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.

    W J Schneider;P T Kovanen;M S Brown;J L Goldstein

  • Activation of human interstitial procollagenase through direct cleavage of the Leu83-Thr84 bond by mast cell chymase.

    Juhani Saarinen;N. Kalkkinen;H. G. Welgus;P. T. Kovanen

Frequent Co-Authors

Mika Ala-Korpela
Mika Ala-Korpela University of Oulu
Markku Kaste
Markku Kaste University of Helsinki
Marja-Riitta Taskinen
Marja-Riitta Taskinen University of Helsinki
Gerald F. Watts
Gerald F. Watts University of Western Australia
Timo E. Strandberg
Timo E. Strandberg University of Helsinki
Vesa M. Olkkonen
Vesa M. Olkkonen University of Helsinki
Christian Ehnholm
Christian Ehnholm Finnish Institute for Health and Welfare (THL)
Amirhossein Sahebkar
Amirhossein Sahebkar Mashhad University of Medical Sciences
Jan Borén
Jan Borén University of Gothenburg
Pekka Saikku
Pekka Saikku University of Oulu

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