Molecular biology, Toll-like receptor, TLR3, Cell biology and Innate immune system are his primary areas of study. His Molecular biology research incorporates themes from Cell culture, RNA, Gene and Complement system, CD46. His Toll-like receptor study contributes to a more complete understanding of Receptor.
His TLR3 research is multidisciplinary, incorporating elements of Signal transducing adaptor protein, Interferon, Virology, RNA silencing and MDA5. The various areas that Tsukasa Seya examines in his Cell biology study include Dendritic cell, TRIF and Interferon regulatory factors. Research on Immune system and Immunology is a part of his Innate immune system study.
Tsukasa Seya mainly investigates Molecular biology, Cell biology, Immunology, Toll-like receptor and CD46. His biological study spans a wide range of topics, including Cell culture, Biochemistry, Transfection, Peptide sequence and Gene. His work carried out in the field of Cell biology brings together such families of science as Receptor, Dendritic cell, TLR3 and TRIF.
His studies deal with areas such as RNA, Endosome and MDA5 as well as TLR3. His study on Toll-like receptor is mostly dedicated to connecting different topics, such as TLR2. His work deals with themes such as Membrane protein, Chinese hamster ovary cell and Complementary DNA, which intersect with CD46.
Tsukasa Seya mostly deals with Immunology, Cell biology, Interferon, Immune system and Cancer research. His study in the field of Antibody, CD46 and Chemokine also crosses realms of Immunoglobulin A. Tsukasa Seya combines subjects such as Receptor, TLR3 and MDA5 with his study of Cell biology.
His Interferon research includes elements of RNA, RIG-I, Molecular biology and In vivo. His research integrates issues of Gene expression and Kinase in his study of Molecular biology. His study in the fields of Dendritic cell and Stimulator of interferon genes under the domain of Immune system overlaps with other disciplines such as Sting.
His scientific interests lie mostly in Interferon, Cell biology, Immunology, Cytotoxic T cell and Cancer research. Tsukasa Seya has researched Interferon in several fields, including RNA, Virus and CTL*. His RNA study typically links adjacent topics like Molecular biology.
His biological study focuses on Signal transduction. His Cytotoxic T cell research incorporates elements of Toll-like receptor, Tumor microenvironment, T cell, CD8 and Immunotherapy. His research in Toll-like receptor is mostly focused on TLR3.
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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction.
Hiroyuki Oshiumi;Misako Matsumoto;Kenji Funami;Takashi Akazawa.
Nature Immunology (2003)
Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells
Misako Matsumoto;Kenji Funami;Masako Tanabe;Hiroyuki Oshiumi.
Journal of Immunology (2003)
Functional annotation of a full-length mouse cDNA collection
J. Kawai;A. Shinagawa;K. Shibata;M. Yoshino.
Nature (2001)
TLR3: interferon induction by double-stranded RNA including poly(I:C).
Misako Matsumoto;Tsukasa Seya.
Advanced Drug Delivery Reviews (2008)
Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling.
Misako Matsumoto;Satomi Kikkawa;Masayoshi Kohase;Kensuke Miyake.
Biochemical and Biophysical Research Communications (2002)
TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β
Hiroyuki Oshiumi;Miwa Sasai;Kyoko Shida;Takashi Fujita.
Journal of Biological Chemistry (2003)
Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers
Keisuke Kataoka;Yuichi Shiraishi;Yohei Takeda;Seiji Sakata.
Nature (2016)
Maturation of Human Dendritic Cells by Cell Wall Skeleton of Mycobacterium bovis Bacillus Calmette-Guérin: Involvement of Toll-Like Receptors
Shoutaro Tsuji;Misako Matsumoto;Osamu Takeuchi;Shizuo Akira.
Infection and Immunity (2000)
Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b.
Tsukasa Seya;Jerry R. Turner;John P. Atkinson.
Journal of Experimental Medicine (1986)
A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling
Masayuki;Naoko Matsunaga;Kaoru Hazeki;Kazuyo Nakamura.
Molecular Pharmacology (2006)
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