D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 90 Citations 27,266 350 World Ranking 417 National Ranking 13

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

Molecular biology, Toll-like receptor, TLR3, Cell biology and Innate immune system are his primary areas of study. His Molecular biology research incorporates themes from Cell culture, RNA, Gene and Complement system, CD46. His Toll-like receptor study contributes to a more complete understanding of Receptor.

His TLR3 research is multidisciplinary, incorporating elements of Signal transducing adaptor protein, Interferon, Virology, RNA silencing and MDA5. The various areas that Tsukasa Seya examines in his Cell biology study include Dendritic cell, TRIF and Interferon regulatory factors. Research on Immune system and Immunology is a part of his Innate immune system study.

His most cited work include:

  • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. (1065 citations)
  • Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells (649 citations)
  • Functional annotation of a full-length mouse cDNA collection (621 citations)

What are the main themes of his work throughout his whole career to date?

Tsukasa Seya mainly investigates Molecular biology, Cell biology, Immunology, Toll-like receptor and CD46. His biological study spans a wide range of topics, including Cell culture, Biochemistry, Transfection, Peptide sequence and Gene. His work carried out in the field of Cell biology brings together such families of science as Receptor, Dendritic cell, TLR3 and TRIF.

His studies deal with areas such as RNA, Endosome and MDA5 as well as TLR3. His study on Toll-like receptor is mostly dedicated to connecting different topics, such as TLR2. His work deals with themes such as Membrane protein, Chinese hamster ovary cell and Complementary DNA, which intersect with CD46.

He most often published in these fields:

  • Molecular biology (31.64%)
  • Cell biology (26.10%)
  • Immunology (22.63%)

What were the highlights of his more recent work (between 2013-2020)?

  • Immunology (22.63%)
  • Cell biology (26.10%)
  • Interferon (12.47%)

In recent papers he was focusing on the following fields of study:

Tsukasa Seya mostly deals with Immunology, Cell biology, Interferon, Immune system and Cancer research. His study in the field of Antibody, CD46 and Chemokine also crosses realms of Immunoglobulin A. Tsukasa Seya combines subjects such as Receptor, TLR3 and MDA5 with his study of Cell biology.

His Interferon research includes elements of RNA, RIG-I, Molecular biology and In vivo. His research integrates issues of Gene expression and Kinase in his study of Molecular biology. His study in the fields of Dendritic cell and Stimulator of interferon genes under the domain of Immune system overlaps with other disciplines such as Sting.

Between 2013 and 2020, his most popular works were:

  • Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers (345 citations)
  • Defined TLR3-specific adjuvant that induces NK and CTL activation without significant cytokine production in vivo (72 citations)
  • DDX60 Is Involved in RIG-I-Dependent and Independent Antiviral Responses, and Its Function Is Attenuated by Virus-Induced EGFR Activation (66 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

His scientific interests lie mostly in Interferon, Cell biology, Immunology, Cytotoxic T cell and Cancer research. Tsukasa Seya has researched Interferon in several fields, including RNA, Virus and CTL*. His RNA study typically links adjacent topics like Molecular biology.

His biological study focuses on Signal transduction. His Cytotoxic T cell research incorporates elements of Toll-like receptor, Tumor microenvironment, T cell, CD8 and Immunotherapy. His research in Toll-like receptor is mostly focused on TLR3.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction.

Hiroyuki Oshiumi;Misako Matsumoto;Kenji Funami;Takashi Akazawa.
Nature Immunology (2003)

1510 Citations

Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells

Misako Matsumoto;Kenji Funami;Masako Tanabe;Hiroyuki Oshiumi.
Journal of Immunology (2003)

961 Citations

Functional annotation of a full-length mouse cDNA collection

J. Kawai;A. Shinagawa;K. Shibata;M. Yoshino.
Nature (2001)

878 Citations

TLR3: interferon induction by double-stranded RNA including poly(I:C).

Misako Matsumoto;Tsukasa Seya.
Advanced Drug Delivery Reviews (2008)

678 Citations

Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling.

Misako Matsumoto;Satomi Kikkawa;Masayoshi Kohase;Kensuke Miyake.
Biochemical and Biophysical Research Communications (2002)

592 Citations

TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β

Hiroyuki Oshiumi;Miwa Sasai;Kyoko Shida;Takashi Fujita.
Journal of Biological Chemistry (2003)

546 Citations

Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

Keisuke Kataoka;Yuichi Shiraishi;Yohei Takeda;Seiji Sakata.
Nature (2016)

524 Citations

Maturation of Human Dendritic Cells by Cell Wall Skeleton of Mycobacterium bovis Bacillus Calmette-Guérin: Involvement of Toll-Like Receptors

Shoutaro Tsuji;Misako Matsumoto;Osamu Takeuchi;Shizuo Akira.
Infection and Immunity (2000)

519 Citations

Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b.

Tsukasa Seya;Jerry R. Turner;John P. Atkinson.
Journal of Experimental Medicine (1986)

475 Citations

A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling

Masayuki;Naoko Matsunaga;Kaoru Hazeki;Kazuyo Nakamura.
Molecular Pharmacology (2006)

470 Citations

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