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Tsukasa Seya

Tsukasa Seya

D-Index & Metrics

Microbiology

D-Index
96
Citations
32424
World Ranking
511
National Ranking
15

Overview

Tsukasa Seya is a researcher affiliated with Hokkaido University in Japan, specializing in immunology and microbiology with a notable focus on immunotherapy and immune responses. Their scholarly work spans various subfields including immunology, epidemiology, molecular biology, infectious diseases, and immunology and allergy. The main topics covered in their research include immunotherapy and immune responses, immune response and inflammation, T-cell and B-cell immunology, influenza virus research studies, immune cell function and interaction, RNA interference and gene delivery, and respiratory viral infections research.

Their recent publications reflect active involvement in advancing understanding of immune mechanisms and vaccine adjuvants. The papers include:

  • "Targeting Toll-like receptor 3 in dendritic cells for cancer immunotherapy" (2020), published in Expert Opinion on Biological Therapy
  • "Toward Establishing an Ideal Adjuvant for Non-Inflammatory Immune Enhancement" (2022), published in Cells
  • "Prophylactic Vaccine Targeting TLR3 on Dendritic Cells Ameliorates Eosinophilic Pneumonia in a Mouse SARS-CoV Infection Model" (2022), published in ImmunoHorizons
  • "Two Modes of Th1 Polarization Induced by Dendritic-Cell-Priming Adjuvant in Vaccination" (2023), published in Cells
  • "ARNAX is an ideal adjuvant for COVID-19 vaccines to enhance antigen-specific CD4 + and CD8 + T-cell responses and neutralizing antibody induction" (2025), published in Journal of Virology

Frequently publishing in journals such as Cells, Expert Opinion on Biological Therapy, ImmunoHorizons, Journal of Virology, and Immunology Letters, their work contributes to the discourse in both basic and applied immunology research.

Tsukasa Seya collaborates regularly with several other researchers, with frequent coauthors including Misako Matsumoto, Masashi Shingai, Tomomi Kawakita, Akari Yamaya, and Yohei Takeda. These collaborations suggest active research networks in immunological studies and vaccine development.

With 19 publications classified under immunology and microbiology, and 7 under medicine, their research emphasis remains strongly embedded in understanding immune cell mechanisms and improving immune targeting strategies, particularly through adjuvant design and dendritic cell modulation.

Best Publications

  • TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction.

    Hiroyuki Oshiumi;Misako Matsumoto;Kenji Funami;Takashi Akazawa

  • Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells

    Misako Matsumoto;Kenji Funami;Masako Tanabe;Hiroyuki Oshiumi

  • Functional annotation of a full-length mouse cDNA collection

    J. Kawai;A. Shinagawa;K. Shibata;M. Yoshino

  • TLR3: interferon induction by double-stranded RNA including poly(I:C).

    Misako Matsumoto;Tsukasa Seya

  • Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

    Keisuke Kataoka;Yuichi Shiraishi;Yohei Takeda;Seiji Sakata

  • Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling.

    Misako Matsumoto;Satomi Kikkawa;Masayoshi Kohase;Kensuke Miyake

  • TIR-containing Adapter Molecule (TICAM)-2, a Bridging Adapter Recruiting to Toll-like Receptor 4 TICAM-1 That Induces Interferon-β

    Hiroyuki Oshiumi;Miwa Sasai;Kyoko Shida;Takashi Fujita

  • Maturation of Human Dendritic Cells by Cell Wall Skeleton of Mycobacterium bovis Bacillus Calmette-Guérin: Involvement of Toll-Like Receptors

    Shoutaro Tsuji;Misako Matsumoto;Osamu Takeuchi;Shizuo Akira

  • A Novel Cyclohexene Derivative, Ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), Selectively Inhibits Toll-Like Receptor 4-Mediated Cytokine Production through Suppression of Intracellular Signaling

    Masayuki;Naoko Matsunaga;Kaoru Hazeki;Kazuyo Nakamura

  • Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b.

    Tsukasa Seya;Jerry R. Turner;John P. Atkinson

  • Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection

    Kenya Honda;Shinya Sakaguchi;Chigusa Nakajima;Ai Watanabe

  • Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall

    Shoutaro Tsuji;Junji Uehori;Misako Matsumoto;Yasuhiko Suzuki

  • Riplet/RNF135, a RING Finger Protein, Ubiquitinates RIG-I to Promote Interferon-β Induction during the Early Phase of Viral Infection

    Hiroyuki Oshiumi;Misako Matsumoto;Shigetsugu Hatakeyama;Tsukasa Seya

  • Teleost TLR22 recognizes RNA duplex to induce IFN and protect cells from birnaviruses.

    Aya Matsuo;Hiroyuki Oshiumi;Tadayuki Tsujita;Hiroshi Mitani

  • Subcellular Localization of Toll-Like Receptor 3 in Human Dendritic Cells

    Unknown

  • Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3

    Dai Iwakiri;Li Zhou;Mrinal Samanta;Misako Matsumoto

  • Prediction of the prototype of the human Toll-like receptor gene family from the pufferfish, Fugu rubripes, genome

    Hiroyuki Oshiumi;Tadayuki Tsujita;Kyoko Shida;Misako Matsumoto

  • Tumor-Secreted Lactic Acid Promotes IL-23/IL-17 Proinflammatory Pathway

    Hiroaki Shime;Masahiko Yabu;Takashi Akazawa;Ken Kodama

  • Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis.

    Tomohiro Hirahashi;Misako Matsumoto;Kaoru Hazeki;Yoshiko Saeki

  • Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

    Vanessa Sancho-Shimizu;Rebeca Pérez de Diego;Lazaro Lorenzo;Rabih Halwani

  • The mechanism of discordant xenograft rejection.

    Shuji Miyagawa;Hajime Hirose;Ryota Shirakura;Yoshihumi Naka

  • 4-mediated cytokine production through suppression of intracellular signaling

    Masayuki;Naoko Matsunaga;Kaoru Hazeki;Kazuyo Nakamura

Frequent Co-Authors

Misako Matsumoto
Misako Matsumoto Aomori University
Hiroyuki Oshiumi
Hiroyuki Oshiumi Kumamoto University
Kumao Toyoshima
Kumao Toyoshima Osaka University
John P. Atkinson
John P. Atkinson Washington University in St. Louis
Masaru Okabe
Masaru Okabe Osaka University
Ichiro Azuma
Ichiro Azuma Hokkaido University
Shizuo Akira
Shizuo Akira Osaka University
Taroh Kinoshita
Taroh Kinoshita Osaka University
Yusuke Yanagi
Yusuke Yanagi Kyushu University

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