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Immunology

D-Index
104
Citations
35334
World Ranking
622
National Ranking
58

Medicine

D-Index
105
Citations
35847
World Ranking
6827
National Ranking
658

Overview

B. Paul Morgan is affiliated with Cardiff University in the United Kingdom. Their research primarily focuses on medicine, with significant contributions spanning neurology, immunology, cardiology and cardiovascular medicine, physiology, and molecular biology. Their work addresses multiple complex biomedical topics with a particular emphasis on disease mechanisms and treatment development.

The scientist's main research topics include:

  • Complement system in diseases
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Cardiomyopathy and Myosin Studies
  • COVID-19 Clinical Research Studies
  • Barrier Structure and Function Studies
  • SARS-CoV-2 and COVID-19 Research

Recent notable publications by B. Paul Morgan include:

  • "Research priorities for the COVID-19 pandemic and beyond: A call to action for psychological science," 2020, British Journal of Psychology
  • "Discovery of Aficamten (CK-274), a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy," 2021, Journal of Medicinal Chemistry
  • "Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease," 2022, Brain
  • "Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report," 2020, Nature Communications
  • "Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration," 2020, Nature Communications

The frequent co-authors collaborating with Morgan include:

  • Wioleta M. Zelek (49 publications together)
  • Fady I. Malik (17 publications together)
  • Darren T. Hwee (16 publications together)
  • Nikoleta Daskoulidou (13 publications together)
  • Sarah M. Carpanini (12 publications together)

Their work is often published in scientific venues such as:

  • Immunobiology (17 publications)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • Journal of Medicinal Chemistry (5 publications)
  • Brain Behavior and Immunity (5 publications)

This profile reflects a professional engaged deeply in multidisciplinary biomedical research, with a substantial focus on immune system mechanisms, neurodegenerative diseases, cardiovascular medicine, and infectious diseases including COVID-19. Their publication record suggests active collaboration and contribution to the evolving landscape of medical science.

Best Publications

  • Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

    Timothy H.J. Goodship;H. Terence Cook;Fadi Fakhouri;Fernando C. Fervenza

  • C3 glomerulopathy: consensus report

    Matthew C. Pickering;Vivette D. D'agati;Carla M. Nester;Richard J. Smith

  • Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.

    S Meri;B P Morgan;A Davies;R H Daniels

  • Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts

    Mark S Cragg;Suzanne M Morgan;H T Claude Chan;B Paul Morgan

  • Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome.

    Elena Goicoechea de Jorge;Claire L. Harris;Jorge Esparza-Gordillo;Luis Carreras

  • Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects

    B P Morgan

  • Immunopathology of secondary‐progressive multiple sclerosis

    John W. Prineas;Eunice E. Kwon;Eun‐Sook Cho;Leroy R. Sharer

  • Complement, a target for therapy in inflammatory and degenerative diseases.

    B. Paul Morgan;Claire L. Harris;Claire L. Harris

  • The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation.

    Kathy Triantafilou;Timothy R. Hughes;Martha Triantafilou;B. Paul Morgan

  • Complement deficiency and disease.

    B.Paul Morgan;Mark J Walport

  • Complement components of the innate immune system in health and disease in the CNS.

    Philippe Gasque;Y. D. Dean;Eamon Patrick McGreal;J. VanBeek

  • Soluble Forms of Toll-Like Receptor (TLR)2 Capable of Modulating TLR2 Signaling Are Present in Human Plasma and Breast Milk

    Emmanuel LeBouder;Julia E. Rey-Nores;Neil K. Rushmere;Martin Grigorov

  • Extrahepatic complement biosynthesis: where, when and why?

    B. P. Morgan;P. Gasque

  • Increased Complement Biosynthesis By Microglia and Complement Activation on Neurons in Huntington's Disease☆

    S.K Singhrao;J.W Neal;B.P Morgan;P Gasque

  • The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement.

    S J Piddlesden;H Lassmann;F Zimprich;B P Morgan

  • Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59.

    Aled Clayton;Claire L. Harris;Jacquelyn Court;Malcolm D. Mason

  • Dimerization of complement factor H-related proteins modulates complement activation in vivo

    E. Goicoechea de Jorge;J. J. E. Caesar;T. H. Malik;M. Patel

  • Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.

    P. Gasque;S. K. Singhrao;J. W. Neal;O. Götze

  • Complement Regulatory Proteins

    B. Paul Morgan;Andrew L. Harris

  • Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis.

    S J Piddlesden;M K Storch;M Hibbs;A M Freeman

Frequent Co-Authors

Claire L. Harris
Claire L. Harris Newcastle University
Santiago Rodríguez de Córdoba
Santiago Rodríguez de Córdoba Spanish National Research Council
Awen Gallimore
Awen Gallimore Cardiff University
Susan M. Lea
Susan M. Lea University of Oxford
Seiichi Matsuo
Seiichi Matsuo Nagoya University
Margarita López-Trascasa
Margarita López-Trascasa Autonomous University of Madrid
V. Michael Holers
V. Michael Holers University of Colorado Denver
Pieter Jelle Visser
Pieter Jelle Visser Amsterdam University Medical Centers
Oscar Llorca
Oscar Llorca Spanish National Research Council
Anthony K. Campbell
Anthony K. Campbell Cardiff University

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