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Biology and Biochemistry

D-Index
75
Citations
17767
World Ranking
5390
National Ranking
2555

Overview

Kalipada Pahan is affiliated with Rush University Medical Center in the United States. Their research spans multiple areas within medicine and neuroscience, with a focus on neurology, physiology, molecular biology, cellular and molecular neuroscience, and infectious diseases.

The main topics of their work include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Peroxisome Proliferator-Activated Receptors
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Nuclear Receptors and Signaling

Frequent collaborators in Pahan's research include Malabendu Jana, Ramesh Kumar Paidi, Sumita Raha, Debashis Dutta, and Avik Roy. These coauthors have contributed extensively alongside Pahan to multiple publications.

Some of the recent papers authored or coauthored by Kalipada Pahan are:

  • "Is COVID-19 Gender-sensitive?", 2021, Journal of Neuroimmune Pharmacology
  • "Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo", 2021, Nature Communications
  • "Eugenol, a Component of Holy Basil (Tulsi) and Common Spice Clove, Inhibits the Interaction Between SARS-CoV-2 Spike S1 and ACE2 to Induce Therapeutic Responses", 2021, Journal of Neuroimmune Pharmacology
  • "Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models", 2023, Journal of Clinical Investigation
  • "Activation of PPARα enhances astroglial uptake and degradation of β-amyloid", 2021, Science Signaling

Key publication venues for Pahan's work include NeuroImmune Pharmacology and Therapeutics, Journal of Neuroimmune Pharmacology, The Journal of Immunology, Cells, and Alzheimer's & Dementia. These journals have published multiple studies by this researcher.

Their work contributes frequently to the understanding of neuroimmune interactions, neurodegenerative diseases such as Alzheimer's and Parkinson's, and investigations into mechanisms related to COVID-19.

Best Publications

  • Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages.

    K. Pahan;F. G. Sheikh;A. M. S. Namboodiri;I. Singh

  • Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

    Anamitra Ghosh;Avik Roy;Xiaojuan Liu;Jeffrey H. Kordower

  • HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis

    R N Saha;K Pahan

  • Induction of Glial Fibrillary Acidic Protein Expression in Astrocytes by Nitric Oxide

    Saurav Brahmachari;Yiu K. Fung;Kalipada Pahan

  • Regulation of inducible nitric oxide synthase gene in glial cells.

    Ramendra N. Saha;Kalipada Pahan

  • Fibrillar Amyloid-β Peptides Activate Microglia via TLR2: Implications for Alzheimer’s Disease

    Malabendu Jana;Carlos A. Palencia;Kalipada Pahan

  • Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine.

    Ramendra N. Saha;Xiaojuan Liu;Kalipada Pahan

  • Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease.

    Hemraj B. Dodiya;Christopher B. Forsyth;Robin M. Voigt;Phillip A. Engen

  • MAPK p38 Regulates Transcriptional Activity of NF-κB in Primary Human Astrocytes via Acetylation of p65

    Ramendra N. Saha;Malabendu Jana;Kalipada Pahan;Kalipada Pahan

  • Lipid-lowering drugs

    K. Pahan

  • Cytokine-mediated Induction of Ceramide Production Is Redox-sensitive: IMPLICATIONS TO PROINFLAMMATORY CYTOKINE-MEDIATED APOPTOSIS IN DEMYELINATING DISEASES

    Inderjit Singh;Kalipada Pahan;Mushfiquddin Khan;Avtar K. Singh

  • Ceramide and neurodegeneration: Susceptibility of neurons and oligodendrocytes to cell damage and death

    Arundhati Jana;Edward L. Hogan;Kalipada Pahan

  • Up-regulation of microglial CD11b expression by nitric oxide.

    Avik Roy;Yiu K. Fung;Xiaojuan Liu;Kalipada Pahan

  • Fibrillar Amyloid-β Peptides Kill Human Primary Neurons via NADPH Oxidase-mediated Activation of Neutral Sphingomyelinase IMPLICATIONS FOR ALZHEIMER'S DISEASE

    Arundhati Jana;Kalipada Pahan

  • N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes.

    Kalipada Pahan;Faruk G Sheikh;Aryan M.S Namboodiri;Inderjit Singh

  • Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin.

    Romesh Stanislaus;Kalipada Pahan;Avtar K. Singh;Inderjit Singh

  • Simvastatin Inhibits the Activation of p21ras and Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

    Anamitra Ghosh;Avik Roy;Joanna Matras;Saurav Brahmachari

  • Is COVID-19 Gender-sensitive?

    Shreya Mukherjee;Shreya Mukherjee;Kalipada Pahan;Kalipada Pahan

  • Sphingomyelinase and Ceramide Stimulate the Expression of Inducible Nitric-oxide Synthase in Rat Primary Astrocytes

    Kalipada Pahan;Faruk G. Sheikh;Mushfiquddin Khan;Aryan M.S. Namboodiri

  • Induction of Nitric-oxide Synthase and Activation of NF-κB by Interleukin-12 p40 in Microglial Cells

    Kalipada Pahan;Faruk G. Sheikh;Xiaojuan Liu;Shilo Hilger

Frequent Co-Authors

Inderjit Singh
Inderjit Singh Medical University of South Carolina
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Richard T. Watson
Richard T. Watson University of Georgia
Sankar Ghosh
Sankar Ghosh Columbia University
Avtar K. Singh
Avtar K. Singh Medical University of South Carolina
Charles Wood
Charles Wood University of Nebraska–Lincoln
David A. Bennett
David A. Bennett Rush University Medical Center
John R. Raymond
John R. Raymond Medical College of Wisconsin
Ali Keshavarzian
Ali Keshavarzian Rush University Medical Center

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