World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
104
Citations
94828
World Ranking
322
National Ranking
144

Molecular Biology

D-Index
102
Citations
92549
World Ranking
484
National Ranking
271

Research.com Recognitions

  • 2023 - Foreign Fellow, National Academy of Sciences, India (NASI)
  • 2023 - Member, American Academy of Arts and Sciences
  • 2022 - Member of the National Academy of Medicine (NAM)
  • 2021 - Member of the National Academy of Sciences
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2002 - AAI-BD Biosciences Investigator Award, American Association of Immunologists

Overview

Sankar Ghosh is affiliated with Columbia University in the United States and specializes primarily in the intersecting fields of biochemistry, genetics, molecular biology, immunology, microbiology, and medicine. Their research contributions span several key subfields including immunology, molecular biology, cancer research, oncology, and epidemiology.

The scientist's work prominently addresses molecular and cellular mechanisms within immune systems and cancer biology. Specific topics of research emphasize NF-κB signaling pathways, RNA modifications in cancer, immune cell function and interaction, immune response and inflammation, cancer-related molecular mechanisms, cytokine signaling pathways, and the role of immune cells in cancer.

Sankar Ghosh has been involved in multiple publications with frequent collaborators including Thomas S. Postler, Jingyao Zhao, Yenkel Grinberg-Bleyer, Felipe Batista Leão, and Vincent Guichard. These coauthors have contributed to a significant portion of their research output.

Their recent publication record includes the following papers:

  • c-Rel is a myeloid checkpoint for cancer immunotherapy (2020, Nature Cancer)
  • The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA (2020, Proceedings of the National Academy of Sciences)
  • Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism (2021, Scientific Reports)
  • κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis (2020, Nature Communications)
  • Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration (2022, Nature Communications)

Their scientific articles have appeared frequently in journals such as Proceedings of the National Academy of Sciences, Scientific Reports, Nature Communications, Nature Immunology, and The Journal of Immunology, reflecting a focus on high-impact and specialized outlets within immunology and molecular biology disciplines.

Among awards, Sankar Ghosh has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2007 and received the AAI-BD Biosciences Investigator Award from the American Association of Immunologists in 2002.

Best Publications

  • NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

    Sankar Ghosh;Michael J. May;Elizabeth B. Kopp

  • Shared principles in NF-kappaB signaling

    Matthew S. Hayden;Sankar Ghosh

  • Signaling to NF-kappaB.

    Matthew S. Hayden;Sankar Ghosh

  • Missing Pieces in the NF-κB Puzzle

    Sankar Ghosh;Michael Karin

  • The NF-κB Family of Transcription Factors and Its Regulation

    Andrea Oeckinghaus;Sankar Ghosh

  • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B.

    Amer A. Beg;William C. Sha;Roderick T. Bronson;Sankar Ghosh

  • Inhibition of NF-kappa B by sodium salicylate and aspirin

    Elizabeth Kopp;Sankar Ghosh

  • NF-κB, inflammation, and metabolic disease.

    Rebecca G. Baker;Matthew S. Hayden;Sankar Ghosh

  • Crosstalk in NF-κB signaling pathways

    Andrea Oeckinghaus;Matthew S Hayden;Sankar Ghosh

  • NF-κB, the first quarter-century: remarkable progress and outstanding questions

    Matthew S. Hayden;Sankar Ghosh

  • MyD88 Is an Adaptor Protein in the hToll/IL-1 Receptor Family Signaling Pathways

    Ruslan Medzhitov;Paula Preston-Hurlburt;Elizabeth Kopp;Andrew Stadlen

  • New regulators of NF-kappaB in inflammation.

    Sankar Ghosh;Matthew S Hayden

  • TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

    A. Phillip West;Igor E. Brodsky;Igor E. Brodsky;Christoph Rahner;Dong Kyun Woo

  • Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B.

    Sankar Ghosh;David Baltimore

  • NF-kappaB and the immune response.

    M S Hayden;A P West;S Ghosh

  • Signal transduction through NF-κB

    Michael J May;Sankar Ghosh

  • Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300

    Haihong Zhong;Reinhard E Voll;Sankar Ghosh

  • A Toll-like Receptor That Prevents Infection by Uropathogenic Bacteria

    Dekai Zhang;Guolong Zhang;Matthew S. Hayden;Matthew B. Greenblatt

  • Mitochondria in innate immune responses

    A. Phillip West;Gerald S. Shadel;Sankar Ghosh

  • TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein

    Felix Yarovinsky;Dekai Zhang;John F. Andersen;Gerard L. Bannenberg

Frequent Co-Authors

Michael J. May
Michael J. May University of Pennsylvania
Richard A. Flavell
Richard A. Flavell Yale University
David Baltimore
David Baltimore California Institute of Technology
Kalipada Pahan
Kalipada Pahan Rush University Medical Center
Fulvio D'Acquisto
Fulvio D'Acquisto Queen Mary University of London
Ulf Klein
Ulf Klein University of Leeds
Mercedes Rincon
Mercedes Rincon University of Vermont
Paul Tempst
Paul Tempst Memorial Sloan Kettering Cancer Center
Josef M. Penninger
Josef M. Penninger University of British Columbia
Govind Bhagat
Govind Bhagat Columbia University

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