World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
67
Citations
18290
World Ranking
1563
National Ranking
788

Overview

Gourisankar Ghosh is affiliated with the University of California, San Diego in the United States. Their research primarily spans the field of Biochemistry, Genetics and Molecular Biology, with a focus on molecular biology, immunology, cancer research, infectious diseases, and cellular and molecular neuroscience.

The main topics covered in Ghosh's work include:

  • NF-κB Signaling Pathways
  • Immune Response and Inflammation
  • RNA and protein synthesis mechanisms
  • Interferon and immune responses
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Mitochondrial Function and Pathology

Ghosh has published frequently in a variety of scientific venues, notably in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Proceedings of the National Academy of Sciences
  • eLife
  • Methods in molecular biology

The scientist has collaborated regularly with a number of coauthors, including:

  • Tapan Biswas
  • Kaushik Saha
  • Shandy Shahabi
  • Anirban Chakraborty
  • Tapas K. Hazra

Recent papers by Gourisankar Ghosh include:

  • "Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics," 2020, published in Cell Reports
  • "Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin)," 2021, published in Hypertension
  • "Origin of the Functional Distinctiveness of NF-κB/p52," 2021, published in Frontiers in Cell and Developmental Biology
  • "Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis," 2020, published in Proceedings of the National Academy of Sciences
  • "Structural disruption of exonic stem-loops immediately upstream of the intron regulates mammalian splicing," 2020, published in Nucleic Acids Research

Best Publications

  • 15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

    Daniel S. Straus;Gabriel Pascual;Mei Li;John S. Welch

  • Regulation of protein kinases; controlling activity through activation segment conformation.

    Brad Nolen;Susan Taylor;Gourisankar Ghosh

  • Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA

    Frances E. Chen;De-Bin Huang;Yong-Qing Chen;Gourisankar Ghosh

  • Transcriptional regulation via the NF-κB signaling module

    A Hoffmann;G Natoli;G Ghosh

  • The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation

    Tom Huxford;De-Bin Huang;Shiva Malek;Gourisankar Ghosh

  • Structure of NF-kappa B p50 homodimer bound to a kappa B site.

    Gourisankar Ghosh;G. Van Duyne;Sankar Ghosh;Sankar Ghosh;P. B. Sigler

  • A fourth IκB protein within the NF-κB signaling module

    Soumen Basak;Hana Kim;Jeffrey D. Kearns;Vinay Tergaonkar

  • Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views.

    Frances E Chen;Gourisankar Ghosh

  • Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers

    Giuseppina Bonizzi;Magali Bebien;Dennis C Otero;Kirsten E Johnson-Vroom

  • A novel DNA recognition mode by the NF-kappa B p65 homodimer.

    Yong-Qing Chen;Sankar Ghosh;Gourisankar Ghosh

  • NF-κB dictates the degradation pathway of IκBα

    Erika Mathes;Ellen L O'Dea;Alexander Hoffmann;Gourisankar Ghosh

  • IκBβ, but Not IκBα, Functions as a Classical Cytoplasmic Inhibitor of NF-κB Dimers by Masking Both NF-κB Nuclear Localization Sequences in Resting Cells

    Shiva Malek;Yi Chen;Tom Huxford;Gourisankar Ghosh

  • Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.

    Suhyung Cho;Amy Hoang;Rahul Sinha;Xiang-Yang Zhong

  • Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2.

    Jacky Chi Ki Ngo;Sutapa Chakrabarti;Jian-Hua Ding;Adolfo Velazquez-Dones

  • NF-κB regulation: lessons from structures

    Gourisankar Ghosh;Vivien Ya-Fan Wang;De-Bin Huang;Amanda Fusco

  • PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB

    Han Wei;Benlian Wang;Masaru Miyagi;Yun She

  • Phosphorylation mechanism and structure of serine‐arginine protein kinases

    Gourisankar Ghosh;Joseph A. Adams

  • IκBα Functions through Direct Contacts with the Nuclear Localization Signals and the DNA Binding Sequences of NF-κB

    Shiva Malek;Tom Huxford;Gourisankar Ghosh

  • Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones

    Xiang-Yang Zhong;Jian-Hua Ding;Joseph A. Adams;Gourisankar Ghosh

  • Crystal structure of NF-κB (p50)2 complexed to a high-affinity RNA aptamer

    De Bin Huang;Don Vu;Laura A. Cassiday;Laura A. Cassiday;Jeff M. Zimmerman

Frequent Co-Authors

Alexander Hoffmann
Alexander Hoffmann University of California, Los Angeles
Xiang-Dong Fu
Xiang-Dong Fu Westlake University
Elizabeth A. Komives
Elizabeth A. Komives University of California, San Diego
Susan S. Taylor
Susan S. Taylor University of California, San Diego
Inder M. Verma
Inder M. Verma Salk Institute for Biological Studies
Hemal H. Patel
Hemal H. Patel University of California, San Diego
David M. Roth
David M. Roth University of California San Diego
Nicholas J. G. Webster
Nicholas J. G. Webster University of California, San Diego
Sushil K. Mahata
Sushil K. Mahata University of California, San Diego
George R. Stark
George R. Stark Cleveland Clinic

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Molecular Biology in the USA opens doors to various career paths, many of which now intersect with online education. Students interested in supportive roles might consider a human services online degree, which prepares graduates for roles in community and healthcare services.

For those with a background in teaching or an interest in healthcare communication, transitioning to speech and language pathology is increasingly popular. Discover how to move from teaching to an allied health role by exploring the teacher to slp pathway.

Combining molecular studies with design or quantitative skills leads to even broader options. Programs like an architect online degree offer new avenues for scientific problem-solving, while those inclined toward data and analysis might pursue an online math degree, valuable in research and biotech.

Exploring these online degrees can help tailor your education to your career goals, whether you wish to remain in science or move into related interdisciplinary fields.

Best Scientists Citing Gourisankar Ghosh

Trending Scientists